Results 141 to 150 of about 2,772,421 (294)

Serum methylmalonic acid levels and epilepsy prevalence: Association analysis, exploratory mediation, and clinical corroboration

open access: yesEpileptic Disorders, EarlyView.
Abstract Objective This study aimed to investigate the association between methylmalonic acid (MMA) and epilepsy prevalence and to explore potential inflammatory and nutritional pathways underlying this association. Methods This study included adults aged ≥ 20 years from the National Health and Nutrition Examination Survey (NHANES) 2011–2014.
Ningyu Wei   +5 more
wiley   +1 more source

Genetic testing among patients evaluated for epilepsy surgery

open access: yesEpileptic Disorders, EarlyView.
Abstract Objective Genetic testing performed to identify the underlying etiology of epilepsy has become increasingly common and is now being recommended as part of the presurgical evaluation for epilepsy surgery. This study aimed to characterize the types of genetic tests performed in patients evaluated for epilepsy surgery and assess how genetic ...
Anni Saarela   +7 more
wiley   +1 more source

Occipital irregular delta activity in focal epilepsy

open access: yesEpileptic Disorders, EarlyView.
Abstract Objective Nonspecific occipital irregular delta activity (OID) is a common finding in focal epilepsy (FE). However, the significance of OID and its relationship to the underlying etiology of FE remain largely unstudied. This study aimed to investigate the relationship between OID and the etiology of FE, as well as the relationship between OID ...
Mónika Bessenyei   +3 more
wiley   +1 more source

The effectiveness of adding on or switching antiseizure medications after the first fails to control focal epilepsy: A systematic review of randomized controlled trials

open access: yesEpileptic Disorders, EarlyView.
Abstract Focal epilepsy constitutes 60–70% of epilepsy, and up to half of patients do not achieve seizure freedom with their first antiseizure medication (ASM). When the first ASM fails, evidence guiding whether to switch or add‐on another ASM and which ASMs to use is limited. This review synthesized evidence from randomized controlled trials (RCTs) on
Isaac J. Egesa   +7 more
wiley   +1 more source

Reflex seizures and epilepsy surgery: A network approach case‐based exploration

open access: yesEpileptic Disorders, EarlyView.
Abstract Context Reflex seizures (RS) are defined by their consistent provocation by specific stimuli, encompassing a broad range from elementary sensory inputs to complex cognitive tasks. While RS are often encountered in clinical practice, their surgical management remains sparsely reported and poorly systematized.
Olivier Aron   +6 more
wiley   +1 more source

Sustained seizure freedom with fenfluramine for refractory epilepsy due to 7q32‐q34 deletion syndrome

open access: yes
Epileptic Disorders, EarlyView.
Divya Veerapaneni   +2 more
wiley   +1 more source

Electroclinical phenotypes—genetic characterization of developmental and epileptic encephalopathies in a cohort study

open access: yesEpileptic Disorders, EarlyView.
Abstract Objective Developmental and epileptic encephalopathies (DEEs) are characterized by refractory seizures and frequently recurring epileptic activity with neurodevelopmental delay or regression that usually begin in early life. We aimed to define the relationship between electroclinical features and etiology, as well as the genotype–phenotype ...
Burcu Yaman   +7 more
wiley   +1 more source

KBG syndrome: A scoping review of electroclinical features of patients with epilepsy

open access: yesEpileptic Disorders, EarlyView.
Abstract Background and Objectives KBG syndrome is a rare autosomal developmental disorder caused by pathogenic variants of the ANKRD11 gene. This scoping review aimed to explore all current literature data regarding clinical and electroencephalographic features of patients with KBG syndrome and epilepsy. Materials and Methods We conducted a literature
Stefania Kalampokini   +6 more
wiley   +1 more source

Functional/dissociative seizures as a manifestation of forced normalization in eyelid myoclonia with absence epilepsy

open access: yes
Epileptic Disorders, EarlyView.
Fernando Vasquez‐Lopez   +16 more
wiley   +1 more source

Direct cortical stimulation–evoked symptoms in the human temporal pole: A systematic review

open access: yesEpileptic Disorders, EarlyView.
Abstract The temporal pole represents a key node within temporolimbic networks and may contribute to seizure generation in temporal lobe epilepsy. Direct cortical stimulation (DCS), performed during intracranial presurgical evaluation, is a valuable method for delineating the seizure onset zone by reproducing electro‐clinical features of a patient's ...
Yulia Novitskaya   +1 more
wiley   +1 more source

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