Results 101 to 110 of about 2,582,050 (300)

Drug resistant epilepsy as the consequence of inadequate control of type 1 diabetes

open access: yes
Hypoglycemic encephalopathy (HE) is a type of encephalopathy resulting from extremely low blood glucose level. Symptoms are not specific and can be misdiagnosed very often.
Maria Mazurkiewicz-Bełdzińska   +4 more
core   +1 more source

Accelerated Brain Atrophy in Epilepsy: A Prospective Population‐Based Study

open access: yesAnnals of Neurology, EarlyView.
Objective Previous longitudinal neuroimaging studies suggest that epilepsy is a progressive disorder. To date, these findings have relied largely on populations from tertiary centers, resulting in ascertainment bias, as severely affected individuals are more likely to be rescanned.
Marian Galovic   +6 more
wiley   +1 more source

Language recovery after epilepsy surgery of the Broca's area

open access: yesEpilepsy and Behavior Case Reports, 2018
Epilepsy surgery is indicated in select patients with drug-resistant focal epilepsy. Seizure freedom or significant reduction of seizure burden without risking new neurological deficits is the expected goal of epilepsy surgery.
Lilit Mnatsakanyan   +6 more
doaj   +1 more source

Neutrophil Extracellular Traps Block Fibrinolysis in Ischemic Stroke

open access: yesAnnals of Neurology, EarlyView.
Objectives Intravenous thrombolysis (IVT) failure in acute ischemic stroke (AIS) is frequent, but its causes remain elusive. We investigated whether biologically relevant intrathrombus concentrations of tissue plasminogen activator (tPA) were achieved in failed IVT and whether neutrophil extracellular traps (NETs) contributed to this therapeutic ...
Mialitiana Solo Nomenjanahary   +21 more
wiley   +1 more source

Study on expressions of heat shock 27⁃associated protein 1 and echinoderm microtubule⁃associated protein⁃like 5 in drug⁃resistant epilepsy

open access: yesChinese Journal of Contemporary Neurology and Neurosurgery, 2012
Objective To observe the expressions of heat shock 27 ⁃ associated protein 1 (HSPBAP1) and echinoderm microtubule⁃associated protein⁃like 5 (EML5) in cerebrospinal fluid of drug⁃ resistant epilepsy, and to explore the value in early diagnosis of epilepsy.
Yun CHEN   +6 more
doaj  

Diagnosis and Surgical Treatment of Drug-Resistant Epilepsy

open access: yesBrain Sciences, 2018
Despite appropriate trials of at least two antiepileptic drugs, about a third of patients with epilepsy remain drug resistant (intractable; refractory).
Chinekwu Anyanwu, Gholam K. Motamedi
doaj   +1 more source

[Drug-resistant epilepsy].

open access: yesTidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 2009
Despite the introduction of many new antiepileptic drugs during recent years, about one third of the epilepsy population continue to have drug-resistant seizures. We present two hypotheses on mechanisms of drug-resistant epileptic seizures.The article is based on our own clinical experience and literature identified through a PubMed search using the ...
Karl O, Nakken, Erik, Taubøll
openaire   +1 more source

Hippocampal Seizure‐Related Burden is Associated with Accelerated Long‐Term Forgetting in Focal Epilepsy

open access: yesAnnals of Neurology, EarlyView.
Objective Memory impairment is a frequent comorbidity of focal epilepsy, incompletely explained by seizure frequency or structural pathology. Ictal and postictal hippocampal dysfunction disrupt memory processes, but their cumulative impact remains poorly quantified.
Ionuț‐Flavius Bratu   +5 more
wiley   +1 more source

Benzodiazepine-resistant epilepsy: unraveling molecular mechanisms and developing multimodal therapeutic strategies

open access: yesFrontiers in Neurology
Epilepsy is one of the most common nervous system diseases, which is characterized by recurrent seizures caused by abnormal neuronal discharges in the brain. Drug-resistant epilepsy (DRE) brings great challenges to clinical treatment.
Yanqiu Huang, Yangfan Zhang, Yi Liang
doaj   +1 more source

Paediatric development of radiopharmaceutical imaging agents and radioligand therapeutics

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract This review focuses on the development of radiopharmaceutical imaging agents and radioligand therapeutics for paediatric use. Nuclear medicine plays an important role in the diagnosis and treatment of various childhood conditions, including cancers, infections and brain disorders.
Justin L. Hay   +5 more
wiley   +1 more source

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