Results 171 to 180 of about 33,337 (262)

Sodium‐glucose cotransporter 2 inhibitors and the risk of late onset epilepsy: A real‐world cohort study

Epilepsia, EarlyView.
Abstract Objective Late onset epilepsy (LOE) is associated with substantial morbidity. Sodium‐glucose cotransporter 2 inhibitors (SGLT2i) may exert neuroprotective effects. This study evaluated the association between SGLT2i and risk of LOE among older adults with type 2 diabetes mellitus.
Bing‐Hua Lin, Hui‐Min Huang, Hui‐An Lin, Sheng‐Feng Lin   +3 more
wiley   +1 more source

Exploring pathways leading to drug-resistant epilepsy for patients with cryptogenic new onset refractory status epilepticus. [PDF]

Epilepsia
Hanin A, Marois C, Guillemaud M, Chavez M, Cosme L, Hayatou Z, Besnard A, Goudard G, Masson V, Cousyn L, Cheval M, Denis JA, Alkouri R, Lamari F, Bisulli F, Eschbach K, Farias-Moeller R, Gaspard N, Gerard EE, Giovannini G, Gofton T, Gopaul MT, Kellogg M, Meletti S, Muccioli L, Pasini E, Taraschenko O, Torcida N, Wainwright MS, Yoo JY, Wong N, Bonnefont-Rousselot D, Demeret S, Hirsch LJ, Navarro V.   +34 more
europepmc   +1 more source

Stereo‐EEG mapping of visual working memory with task‐related high‐gamma modulations

Epilepsia, EarlyView.
Abstract Objective We describe a safe, informative, and easy‐to‐implement approach for presurgical mapping of visual working memory (VWM) with stereo‐electroencephalography (SEEG). Methods Twenty‐four patients with drug‐resistant epilepsy, 11–23 years of age, performed a single‐probe change detection VWM task, during SEEG monitoring.
Brian Ervin, Jason Buroker, Taylor Cummins, Anna W. Byars, Craig Scholle, Leonid Rozhkov, Paul S. Horn, Jeffrey R. Tenney, Hansel M. Greiner, James L. Leach, Jesse Skoch, Francesco T. Mangano, Katherine D. Holland, Ravindra Arya   +13 more
wiley   +1 more source

Adjunctive Nutritional Supplementation in Drug-Resistant Epilepsy: A Prospective Observational Study Evaluating Quality of Life and Seizure Outcomes. [PDF]

Cureus
Singh AK, Kumari G.
europepmc   +1 more source

Biofluid‐specific variations in circulating 5′ transfer RNA fragments during ictal and interictal states in experimental temporal lobe epilepsy

Epilepsia, EarlyView.
Abstract Objective Circulating small noncoding RNAs represent potential biomarkers of temporal lobe epilepsy (TLE). Recently, two transfer RNA fragments (tRFs), 5′tRF Glu‐CTC and Gly‐GCC, were found to be elevated in plasma samples collected in advance of a seizure in TLE patients, suggesting they may serve as potential wet biomarkers of seizure risk ...
Marie Soukupova, Elena Perez Morrissey, Annunziata Guarino, Pietro Marino, Cristiana Pareo, Nicolò Birtolo, Saad Zaheer, Rachel Stewart, Ina Woods, Felix Rosenow, Hajo Hamer, Péter Körtvélyessy, Shona Pfeiffer, David C. Henshall, Jochen H. M. Prehn, Michele Simonato   +15 more
wiley   +1 more source

Diffusion Tractography Biomarker for Epilepsy Severity in Children With Drug-Resistant Epilepsy. [PDF]

Ann Clin Transl Neurol
Jeong JW, Lee MH, Uda H, Hwang YH, Behen M, Luat A, Juhász C, Asano E.   +7 more
europepmc   +1 more source

Use of artificial intelligence in magnetic resonance imaging across the epileptic patient's journey: A meta‐analysis of four clinical applications

Epilepsia, EarlyView.
Abstract Objective The application of artificial intelligence/machine learning (AI/ML) to magnetic resonance imaging (MRI) promises to enhance and support clinical decision‐making in epilepsy. However, there currently lacks an appropriate assessment of clinical utility and study rigor of current AI/ML‐driven models that are targeted toward supporting ...
Judy Chen, Ella Sahlas, Yigu Zhou, Natalie Chen, Jim Xie, Farhan Wadia, Lorenzo Caciagli, Aristides Hadjinicolaou, Alexander G. Weil, Roy W. Dudley, Dewi V. Schrader, Andrea Bernasconi, Neda Bernasconi, Boris C. Bernhardt   +13 more
wiley   +1 more source

Efficacy and Safety of Clobazam Adjunctive Therapy in Pediatric Patients with Drug-Resistant Epilepsy. [PDF]

Drug Des Devel Ther
Yu L, Chen S, Zhang Z, Hu Y, Fang Y, Mao F, Wang S, Yu Z, Li X, Dai H.   +9 more
europepmc   +1 more source

Compound heterozygous SLC12A5 variants expand the molecular and functional spectrum of KCC2‐developmental and epileptic encephalopathy

Epilepsia, EarlyView.
Overview of the multimodal experimental approach integrating clinical, genetic, in silico, and in vitro investigations. Clinical: Representative EEG recording setup and ictal traces from affected patients. Genetic: Pedigrees for Families A and B highlighting the inheritance of the four identified SLC12A5 variants (A1, A2, B1, B2).
Mira Hamze, Robyn Whitney, Dorothée Ville, Nathalie Villeneuve, Anna‐Maria Hartmann, Lisa Becker, Jens Hausmann, Jinwei Zhang, Cathy Brier, Lucie I. Pisella, Perrine Friedel, Audrey Labalme, Eudeline Alix, Nicolas Chatron, Damien Sanlaville, Sylvie Gory‐Fauré, Eric Denarier, Christophe Porcher, Gaetan Lesca, Igor Medina   +19 more
wiley   +1 more source