Results 191 to 200 of about 2,772,421 (294)

Epigenetic ageing is accelerated in drug-resistant epilepsy and dynamically modulated during ketogenic diet therapy. [PDF]

EBioMedicine
Gervin K, Kverneland M, Nakken KO, Rudi K, Iversen PO, Selmer KK.   +5 more
europepmc   +1 more source

Abnormal KCC2 expression and function in a mouse model of epilepsy and tuberous sclerosis complex

Epilepsia, EarlyView.
Abstract Objective Drug‐resistant epilepsy is a common, severe manifestation of the genetic disorder tuberous sclerosis complex (TSC). Although significant mechanistic and therapeutic advances have been made in TSC, treatments for seizures remain largely ineffective.
Dongjun Guo, Lirong Han, Nicholas R. Rensing, Laura A. Jansen, Michael Wong   +4 more
wiley   +1 more source

Real-world use of Cenobamate in pediatric drug-resistant epilepsy: A European multicenter retrospective study. [PDF]

Epilepsia Open
Makridis KL, Bast T, Auvin S, Krsek P, Ebel M, Breuer E, Beckhaus M, Bašovský M, Danhofer P, Horák O, Orsini A, Ramos Rivera GA, Medřická H, Syrbe S, Kaindl AM.   +14 more
europepmc   +1 more source

Change in clobazam pharmacokinetics after introduction of cenobamate

Epilepsia, EarlyView.
Abstract Cenobamate is a new antiseizure medication with an unusually high seizure‐free rate, resulting in frequent use in patients with drug‐resistant epilepsy. Many of these patients are taking clobazam (CLB) at baseline. Cenobamate has important interactions with CLB, requiring CLB dose adjustment in conjunction with cenobamate titration.
Melissa R. Osborn, Kevin F. Haas, Bassel W. Abou‐Khalil   +2 more
wiley   +1 more source

Efficacy of intravenous immunoglobulin in children with drug-resistant epilepsy. [PDF]

Front Neurol
Ebdalla A, Scantlebury MH, Appendino JP, Ho A, Jacobs J.   +4 more
europepmc   +1 more source

Epileptic arousals: A neglected clinical entity

Epilepsia, EarlyView.
Abstract Objective Epileptic arousals (EAs) are seizures characterized solely by arousal from sleep. EAs are unrecognized in current seizure classifications. Their subtle semiology and inconsistently detectable ictal activity in scalp electroencephalography (EEG) complicate differentiation from physiological arousals (PAs). This study characterizes EAs
Lea Fisel, Nóra Pető, Sotirios Kalousios, Nicolas Zabler, Armin Brandt, Peter C. Reinacher, Dieter Riemann, Mohammad F. Khazali, Andreas Schulze‐Bonhage   +8 more
wiley   +1 more source

Peripartum Management of Vagus Nerve Stimulation and Antiseizure Medications During Two Pregnancies in a Woman With Drug-Resistant Epilepsy: A Case Report. [PDF]

Clin Case Rep
Ono M, Asaka R, Tanaka Y, Fuseya C, Kikuchi N, Miyamoto T.   +5 more
europepmc   +1 more source

Enhancing quality of mental health service for veterans with seizures

Epilepsia, EarlyView.
Abstract Psychiatric disorders are commonly identified in people with seizures (PWS). Comorbid mood, anxiety, and trauma‐ and stressor‐related disorders are highly prevalent and not consistently recognized or treated promptly. Veterans with seizures are particularly vulnerable to neuropsychiatric comorbidities, including a higher prevalence of ...
Maria Raquel Lopez, W. Curt LaFrance Jr., Kristen Mordecai, Anna E. Blanken, Mary Jo Pugh, Krista Ocier, Hamada Altalib   +6 more
wiley   +1 more source