Results 191 to 200 of about 33,337 (262)

Listening across frequencies: Capturing seizures of all patients to advance antiseizure medication development

Epilepsia, EarlyView.
Abstract Seizure frequency has been the primary endpoint in epilepsy trials, with enrollment usually requiring ≥4 seizures per month. This threshold is more and more misaligned with clinical reality, as the availability of more treatment options has reduced baseline seizure burden, with a risk of excluding a proportion of patients from trials. Although
Stéphane Auvin, Jacqueline French
wiley   +1 more source

Efficacy and safety of adjunctive clobazam in Chinese patients with drug-resistant epilepsy: a single-center real-world study. [PDF]

Front Neurol
Zhang Y, Liu X, Su Z, Xu X, She Y, Chen S, Zhou L.   +6 more
europepmc   +1 more source

Picture naming: Stereoelectroencephalography and connectivity insights

Epilepsia, EarlyView.
Abstract Objective This study investigates the neural substrates of picture naming (PN) using stereoelectroencephalographic (SEEG) stimulations and evaluates the contribution of white matter (WM) fascicles related to the basal temporal language area (BTLA) to the broader functional PN network.
Insafe Mezjan, Fabien Rech, Olivier Aron, Louis Maillard, Sophie Colnat‐Coulbois   +4 more
wiley   +1 more source

Locating the epileptogenic zone for drug-resistant epilepsy through neuroelectrophysiological brain network topology. [PDF]

Front Neurosci
Zhang W, Shi Z, Kong W, Gong Y, Lin W, Wu Z, Han Y, Liu Y, Wang T.   +8 more
europepmc   +1 more source

Corticocortical evoked potential amplitude is altered by cortical stimulation in epilepsy

Epilepsia, EarlyView.
Abstract Objective Neurostimulation is an established therapy for drug‐resistant epilepsy, but optimizing stimulation parameters remains a major challenge. Corticocortical evoked potential (CCEP) amplitude may serve as an immediate biomarker of neurostimulation effects, enabling rapid parameter optimization.
Bethany J. Stieve, Aaron F. Struck, Dillon Scott, Richard Chappell, Andrew T. Knox   +4 more
wiley   +1 more source

Clinical outcomes and learning curve of MRgLITT system for drug-resistant epilepsy in China: A single-center retrospective study. [PDF]

Epilepsia Open
Chen S, Dai Y, Fan X, Wang Y, Wei P, Shan Y, Zhao G.   +6 more
europepmc   +1 more source

Low diagnostic yield of presurgical genetic testing in adult patients with epilepsy

Epilepsia, EarlyView.
Abstract Objective To determine the diagnostic yield of genetic testing in patients undergoing presurgical evaluation for epilepsy. Methods We conducted a cohort study including 115 adult patients who underwent presurgical evaluation in the Calgary Epilepsy Program between 2019 and 2023 and who had undergone research exome sequencing.
Clara Jünemann, Amanda Stuart, Navprabhjot Kaur, Samuel Wiebe, Nathalie Jette, Shaily Singh, Felippe Borlot, Susanne Knake, The Calgary Comprehensive Epilepsy Program Collaborators, Paolo Federico, Colin Josephson, William Murphy, Andrea Salmon, Guillermo Delgado Garcia, Walter Hader, Ping Yee Billie Au, Karl Martin Klein   +16 more
wiley   +1 more source

Cost-effectiveness analysis of vagus nerve stimulation in drug-resistant epilepsy. [PDF]

Acta Epileptol
Xiong W, Lu L, Zhang Y, Egbuta CO, Wu X, Sander JW, Zhou D.   +6 more
europepmc   +1 more source

Seizure relapse in new onset epilepsy: It is not always drug resistance

Epilepsia, EarlyView.
Abstract Objective Seizure recurrence in new onset epilepsy (NOE) can result from various factors. Although drug ineffectiveness is frequently investigated, other causes—such as nonadherence, inadequate treatment, nonepileptic events (e.g., functional/dissociative), or acute symptomatic seizures—also impact patient outcomes.
Cecilia Catania, Eric Menetre, Aikaterini Fitsiori, Felix Tobias Kurz, Gabriela Moreno Legast, Serge Vulliemoz, Mathieu Genoud, Pierre Mégevand, Roland Wiest, Fabienne Picard, Sandor Beniczky, Margitta Seeck   +11 more
wiley   +1 more source

Real-world outcomes of ketogenic diet therapy in children with drug-resistant epilepsy in a prospective cohort study. [PDF]

Sci Rep
Han R, Xu Y, Sun J, Guo Q, Du K, Dong Y, Li X, Zhang L, Chen H, Li L, Xu D, Duan J, Li B, Zhang X, Zhu C.   +14 more
europepmc   +1 more source