Results 191 to 200 of about 2,582,050 (300)

Predicting post-surgical visuospatial memory performance in people with drug-resistant epilepsy. [PDF]

Epileptic Disord
Colucci E, Saj A, Charbonneau S, Denault C, Malenfant A, Rouleau I, Nguyen DK, Boucher O.   +7 more
europepmc   +1 more source

Complementary predictive value of electromagnetic source imaging and hemodynamic responses in epilepsy surgery: A quantitative spatial analysis

Epilepsia, EarlyView.
Abstract Objective Accurate presurgical evaluation should assess not only the location but also the spatial extent of epileptic activity relative to the surgical cavity, a practical approximation of the epileptogenic zone. We evaluated how electromagnetic source imaging (EMSI) and hemodynamic responses to epileptic discharges relate to the surgical ...
Chifaou Abdallah, Edouard Delaire, Arielle Dascal, Aura González, Zhengchen Cai, Tanguy Hedrich, Hassan Khajehpour, Satoru Ikemoto, Masataka Tanaka, Boris C. Bernhardt, Eliane Kobayashi, Jean Gotman, Birgit Frauscher, Christophe Grova   +13 more
wiley   +1 more source

Ketogenic diet therapies for the treatment of drug-resistant epilepsy in children and adults: A systematic review. [PDF]

PLoS One
Vaccarezza MM, Sanguine VL, Balaciano G.
europepmc   +1 more source

SUDEP and mortality in developmental and epileptic encephalopathies: A meta‐analysis of randomized clinical trials and extension studies

Epilepsia, EarlyView.
Abstract Objective Developmental and epileptic encephalopathies (DEEs) are associated with high premature mortality and increased risk of sudden unexpected death in epilepsy (SUDEP). However, epidemiological data remain limited, particularly for specific syndromes such as Dravet syndrome (DS), Lennox–Gastaut syndrome (LGS), and infantile epileptic ...
Pierludovico Moro, Maria Sole Borioni, Adolfo Mazzeo, Enrico Cocchi, Carlo Di Bonaventura, Emanuele Cerulli Irelli   +5 more
wiley   +1 more source

Insights into ANKRD11‐related epilepsy from 163 people

Epilepsia, EarlyView.
Abstract Objective Ankyrin repeat domain 11 gene (ANKRD11) is the key disease gene for autosomal dominant KBG syndrome, and a subset of affected individuals develop epilepsy. However, comprehensive characterization of epilepsy‐related phenotypes and genotype–phenotype correlations in ANKRD11 variant carriers remains limited.
Song Su, Jian Ma, Qi Zhang, Wandong Hu, Ying Ren, Wenchao Zhang, Hongwei Zhang   +6 more
wiley   +1 more source

Progress report on new epilepsy treatments: A summary of the Eighteenth Eilat Conference on New Antiepileptic Drugs and Devices (EILAT XVIII). I. Treatments in preclinical and early clinical development

Epilepsia, EarlyView.
Abstract Over the last 34 years, the Eilat Conference on New Antiepileptic Drugs and Devices has provided an interactive forum for stakeholders to discuss investigational and recently licensed treatments for seizures and epilepsy. The Eighteenth Eilat Conference on New Antiepileptic Drugs and Devices (EILAT XVIII) took place in Madrid, Spain, on May 3 ...
Meir Bialer, Cecilie Johannessen Landmark, Matthias J. Koepp, Emilio Perucca, Piero Perucca, Torbjörn Tomson, H. Steve White, Elaine Wirrell   +7 more
wiley   +1 more source

Vagus nerve stimulation in drug-resistant epilepsy: Surgical technique from a tertiary epilepsy center. [PDF]

Surg Neurol Int
Vilá-Cabello D, Castelo-Pablos MF, Deustúa-Hernández D, Fragoso-Serrano H, Loza-Jasso A, Ortiz-Cuevas M, Espinosa-Becerra FS, Paredes-Aragón E, Mejía-Pérez SI, Cervera-Martínez C.   +9 more
europepmc   +1 more source

Magnetoencephalographic source imaging improves localization of the epileptogenic zone in multimodal imaging evaluation

Epilepsia, EarlyView.
Abstract Objective To assess the added diagnostic value of magnetoencephalographic source imaging (MSI) beyond conventional magnetic resonance imaging (MRI) and fluorodeoxyglucose–positron emission tomography (FDG‐PET) in localizing the epileptogenic zone, with stereo‐electroencephalography (SEEG) and surgical resection serving as reference standards ...
Romain Bouet, Marc Hermier, Karine Ostrowsky‐Coste, Sebastien Daligault, Sandrine Bouvard, Hélène Catenoix, Alexandra Montavont, Sébastien Boulogne, François Mauguière, Sylvain Rheims, Julien Jung   +10 more
wiley   +1 more source

A first in disease trial of the safety, tolerability, and anti-seizure effects of ES-481 in drug-resistant epilepsy. [PDF]

Epilepsia Open
Foster EC, Millist L, Germaine J, Chamorro S, Roberts C, Nicolo JP, Hosking S, Perucca P, Mullen S, Robinson H, Wharrie R, Walsh B, Reutens D, Irwin K, Zeng H, Niecestro R, O'Brien TJ.   +16 more
europepmc   +1 more source

Diagnostic yield and copy number variants findings in 219 adult patients with developmental and epileptic encephalopathy

Epilepsia, EarlyView.
Abstract In a clinical setting, exome sequencing (ES) with copy number variant (CNV) analysis is currently the most effective approach for developmental and epileptic encephalopathies (DEE). However, trio‐based ES is often not feasible in adults, its costs remain prohibitive in certain health care settings, and computational tools for CNV calling still
Laura Licchetta, Giulia Bruschi, Tania Giangregorio, Carlotta Stipa, Elisa Mannini, Raffaella Minardi, Barbara Mostacci, Valentina Tontini, Tommaso Pippucci, Francesca Bisulli, Pamela Magini   +10 more
wiley   +1 more source