Results 21 to 30 of about 8,194,451 (253)
Predicting Drug-Target Interactions for New Drug Compounds Using a Weighted Nearest Neighbor Profile. [PDF]
PLoS ONE, 2013 In silico discovery of interactions between drug compounds and target proteins is of core importance for improving the efficiency of the laborious and costly experimental determination of drug-target interaction.
Twan van Laarhoven, Elena Marchiori
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BMC Bioinformatics, 2021 Background Wet-lab experiments for identification of interactions between drugs and target proteins are time-consuming, costly and labor-intensive. The use of computational prediction of drug–target interactions (DTIs), which is one of the significant ...
Ali Ghanbari Sorkhi +3 more
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Machine learning for Drug-Target Interaction Prediction
, 2022 This thesis proposes deep learning frameworks to learn and decode the drug"target interaction. The deep learning model is inspired by the drug"target interaction mechanism and exploits a rich external data resource.
Minh Tri Nguyen (16927608)
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A Novel Deep Neural Network Technique for Drug–Target Interaction
Pharmaceutics, 2022 Drug discovery (DD) is a time-consuming and expensive process. Thus, the industry employs strategies such as drug repositioning and drug repurposing, which allows the application of already approved drugs to treat a different disease, as occurred in the ...
Jackson G. de Souza +2 more
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A semi-supervised method for drug-target interaction prediction with consistency in networks. [PDF]
PLoS ONE, 2013 Computational prediction of interactions between drugs and their target proteins is of great importance for drug discovery and design. The difficulties of developing computational methods for the prediction of such potential interactions lie in the ...
Hailin Chen, Zuping Zhang
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Drug Target Commons 2.0 : a community platform for systematic analysis of drug target interaction profiles [PDF]
, 2018 Drug Target Commons (DTC) is a web platform (database with user interface) for community-driven bioactivity data integration and standardization for comprehensive mapping, reuse and analysis of compound-target interaction profiles.
Wennerberg, Krister +9 more
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Drug-drug interactions in the hospital [PDF]
, 2007 Introduction Drug interaction screening programs are an important tool to check prescriptions of multiple drugs for potential drug-drug interactions (pDDIs). Several programs are available on the market.
Vonbach, Priska
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BMC Bioinformatics, 2022 Predicting drug–target interactions (DTIs) has become an important bioinformatics issue because it is one of the critical and preliminary stages of drug repositioning.
Reza Hassanzadeh +1 more
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Computational Discovery of Putative Leads for Drug Repositioning through Drug-Target Interaction Prediction. [PDF]
PLoS Computational Biology, 2016 De novo experimental drug discovery is an expensive and time-consuming task. It requires the identification of drug-target interactions (DTIs) towards targets of biological interest, either to inhibit or enhance a specific molecular function.
Edgar D Coelho +2 more
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Digoxin + Cyclosporine - contextualized potential drug-drug interaction clinical algorithm
, 2020 An algorithm developed for research purposes that summarizes the potential drug-drug interaction between digoxin and cyclosporine. The information is not advice, and should not be treated as such.
Contributors to the A Minimum Representation of Potential Drug-Drug Interaction Knowledge and Evidence - Technical and User-centered Foundation Specification
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