Results 21 to 30 of about 888,632 (296)
Molecules, 2022 Drug-target interaction (DTI) prediction through in vitro methods is expensive and time-consuming. On the other hand, computational methods can save time and money while enhancing drug discovery efficiency.
Aida Tayebi +6 more
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A Federated Learning Benchmark for Drug-Target Interaction
Companion Proceedings of the ACM Web Conference 2023, 2023 This paper is the accepted version of ACM copyrighted material published at the WWW'23 ...
Gianluca Mittone +4 more
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Quantitative Biology, 2023 Computational methods for DDIs and DTIs prediction are essential for accelerating the drug discovery process. We proposed a novel deep learning method DeepDrug, to tackle these two problems within a unified framework.
Qijin Yin +5 more
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BMC Bioinformatics, 2018 Background Identification of drug-target interactions acts as a key role in drug discovery. However, identifying drug-target interactions via in-vitro, in-vivo experiments are very laborious, time-consuming.
Ingoo Lee, Hojung Nam
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Biases of Drug–Target Interaction Network Data [PDF]
, 2014 Network based prediction of interaction between drug compounds and target proteins is a core step in the drug discovery process. The availability of drugtarget interaction data has boosted the development of machine learning methods for the in silico prediction of drugtarget interactions.
Laarhoven, T. van, Marchiori, E.
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Drug-target interaction prediction using semi-bipartite graph model and deep learning
BMC Bioinformatics, 2020 Background Identifying drug-target interaction is a key element in drug discovery. In silico prediction of drug-target interaction can speed up the process of identifying unknown interactions between drugs and target proteins.
Hafez Eslami Manoochehri +1 more
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Predicting Drug-Target Interactions for New Drug Compounds Using a Weighted Nearest Neighbor Profile. [PDF]
PLoS ONE, 2013 In silico discovery of interactions between drug compounds and target proteins is of core importance for improving the efficiency of the laborious and costly experimental determination of drug-target interaction.
Twan van Laarhoven, Elena Marchiori
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Drug-drug interactions in the hospital [PDF]
, 2007 Introduction Drug interaction screening programs are an important tool to check prescriptions of multiple drugs for potential drug-drug interactions (pDDIs). Several programs are available on the market.
Vonbach, Priska
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BMC Bioinformatics, 2021 Background Wet-lab experiments for identification of interactions between drugs and target proteins are time-consuming, costly and labor-intensive. The use of computational prediction of drug–target interactions (DTIs), which is one of the significant ...
Ali Ghanbari Sorkhi +3 more
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Drug-Disease Severity and Target-Disease Severity Interaction Networks in COVID-19 Patients [PDF]
, 2022 Drug interactions with other drugs are a well-known phenomenon. Similarly, however, pre-existing drug therapy can alter the course of diseases for which it has not been prescribed.
Verena Schöning +3 more
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