Results 91 to 100 of about 12,292,416 (404)

Enhanced removal of Chloramphenicol drug by low cost superabsorbent hydrogel nanocomposite: Optimization, isotherm, and thermodynamic modelling non-linear [PDF]

open access: yesCaspian Journal of Environmental Sciences
In this work, an eco-friendly, stable, simple, new super adsorbent adsorption properties based on biopolymer sodium alginate was successfully deliberated by a combination of a simple crosslinking method.
Lubna A. Al-Shik   +2 more
doaj   +1 more source

Genomics of Drug Sensitivity in Cancer (GDSC): a resource for therapeutic biomarker discovery in cancer cells

open access: yesNucleic Acids Res., 2012
Alterations in cancer genomes strongly influence clinical responses to treatment and in many instances are potent biomarkers for response to drugs. The Genomics of Drug Sensitivity in Cancer (GDSC) database (www.cancerRxgene.org) is the largest public ...
Wanjuan Yang   +16 more
semanticscholar   +1 more source

Picoliter-volume inkjet printing into planar microdevice reservoirs for low-waste, high-capacity drug loading. [PDF]

open access: yes, 2017
Oral delivery of therapeutics is the preferred route for systemic drug administration due to ease of access and improved patient compliance. However, many therapeutics suffer from low oral bioavailability due to low pH and enzymatic conditions, poor ...
Bogdanoff, Derek B   +6 more
core   +1 more source

Biophysical analysis of angiotensin II and amyloid‐β cross‐interaction in aggregation and membrane disruption

open access: yesFEBS Letters, EarlyView.
Angiotensin II (AngII), a neuropeptide, interacts with amyloid‐β (Aβ), a key player in Alzheimer's disease. This study reveals that AngII reduces Aβ aggregation and membrane disruption in vitro. Biophysical assays and molecular modeling suggest AngII binds disordered Aβ forms, potentially modulating early amyloidogenic events and contributing to ...
Mohsen Habibnia   +5 more
wiley   +1 more source

Evaluation the anticancer and biological activity by new amide compound of trimethoprim with some of its complexes [PDF]

open access: yesCaspian Journal of Environmental Sciences
By reacting trimethoprim and hippuric acid at a molecular weight of 1, the amide ligand molecule was produced. By reacting ligands with CoCl2.2H2O, NiCl2.6H2O, and K2PtCl6 in a 2:1 [L:M] mole ratio, cobalt (II), nickel (II), and platinum (IV) complexes ...
Alaa Abdullah Majeed   +1 more
doaj   +1 more source

Poly Lactic-co-Glycolic Acid (PLGA) as Biodegradable Controlled Drug Delivery Carrier.

open access: yesPolymers, 2011
In past two decades poly lactic-co-glycolic acid (PLGA) has been among the most attractive polymeric candidates used to fabricate devices for drug delivery and tissue engineering applications.
Hirenkumar K. Makadia, S. Siegel
semanticscholar   +1 more source

Drug Distribution and Stent Retention of Drug Eluting Stents [PDF]

open access: yes, 2008
In this paper the examinations of drug eluting coronary stents are shown, such as the morphology of the coatings before expansion, drug distribution, the methodology and the value of stent retention.
Balázs, T.   +3 more
core  

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

open access: yesFEBS Letters, EarlyView.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer   +7 more
wiley   +1 more source

The processes of reform in Victoria’s alcohol and other drug sector, 2011-2014 [PDF]

open access: yes
This paper explores issues and concerns related to the 2014 alcohol and other drug sector recommissioning process in Victoria. Overview In mid-2014, the Victorian Alcohol and Drug Association approached the Drug Policy Modelling Program, at the ...
Drug Policy Modelling Program
core  

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