Results 151 to 160 of about 957,503 (357)

A Biomimetic Nanoparticle System Intercepts and Degrades Thrombospondin‐1 to Restore Vascular Homeostasis After Ischemic Injury

Advanced Science, EarlyView.
TAX2‐NPs capture extracellular TSP‐1 in the injured liver and promote its macrophage‐mediated autophagic degradation. This process blocks TSP‐1/CD47 signaling, restores VEGFR2‐AKT activity, preserves endothelial function, and mitigates hepatic ischemia‐reperfusion injury.
Haorui Wang, Xiandi Meng, Yanbao Xin, Kuirong Mao, Huizhu Tan, Changkai Ma, Xiuxiu Cong, Mengfei Zhao, Meiling Yu, Si Chen, Yue Hou, Yong‐Guang Yang, Tianmeng Sun   +12 more
wiley   +1 more source

LATERAL HYPOTHALAMIC GLUTAMATERGIC INPUTS TO VTA GLUTAMATERGIC NEURONS MEDIATE PRIORITIZATION OF INNATE DEFENSIVE BEHAVIOR OVER FEEDING

IBRO Neuroscience Reports, 2023
M. Flavia Barbano, Shiliang Zhang, Emma Chen, Orlando Espinoza, Uzma Mohammad, Yocasta Alvarez-Bagnarol, Bing Liu, Marisela Morales   +7 more
doaj   +1 more source

URBAN RESIDENTS ATTITUDES TOWARDS PEOPLE WITH DRUG ABUSE IN FIVE DISTRICTS OF CONCEPCION COMMUNE, CHILE [PDF]

, 2019
Patricia Jara Concha, Francisco Cumsille
openalex   +1 more source

BIOPSY PROVEN ACUTE INTERSTITIA NEPHRITIS SECONDARY TO NON-STEROIDAL ANTI-INFLAMMATORY DRUGS ABUSE IN A SIXTY TWO YEAR OLD MAN

, 2023
Shitu A.O Uduagbamen P.K
openalex   +2 more sources

Paternal Caffeine Exposure Programs Offspring Stress Vulnerability via Sperm Dlk1‐Dio3 Imprinting‐Directed Remodeling of a Novel Neural Circuit

Advanced Science, EarlyView.
The study elucidates that paternal preconception stress can drive offspring hyperresponsivity of the stress system via hypomethylation of a specific DNA region in sperm. This key link is confirmed in a cohort of prospective fathers: the epigenetic alteration is associated with elevated stress hormone levels.
Mengxi Lu, Gaole Dai, Sen Zhu, Shuai Zhang, Tingting Wang, Yuan Meng, Fang Yang, Xiaoyi Han, Hui Wang, Hao Kou, Dan Xu   +10 more
wiley   +1 more source

CASE TOWARDS INDONESIAN CITIZENS CONCERNING THE ABUSE OF DRUGS IN INDONESIA

, 2020
Ayumi Nur, Exsi Wulandari, Yoga Maulana
openalex   +2 more sources

Drug Abuse Among Communities in Riau Province [PDF]

, 2018
Syarifah Hidayah Fatriah
openalex   +1 more source

Development of a Human 3D Immune‐Competent Neurovascular Model Enabling Time‐Resolved Monitoring of Neuroinflammatory Dynamics and Neuroimmune Interactions

Advanced Science, EarlyView.
Neuroinflammation alters blood–brain barrier integrity and contributes to neurological disorders, yet existing models lack human immune complexity. This study presents a 3D, immune‐responsive platform that reconstructs key neurovascular components and enables real‐time monitoring.
Pavlo Gordiichuk, Jing Bai, Olurotimi A. Bolonduro, Andrew M. Silverman, Robert Madison Green, Jason H. Lasser, Paul W. Fleming, Lishomwa C. Ndhlovu, James F. Saunders, Dmitry Shvartsman   +9 more
wiley   +1 more source

A STUDY ON DRUG ABUSE IN ZAGAZIG UNIVERSITY STUDENTS, EGYPT: CROSS SECTIONAL STUDY [PDF]

, 2017
Dalia M. Amin, Zeinab Mohamed
openalex   +1 more source

A Viscous DES‐AAV‐Foxo1 Delivery System With High Transfection Efficiency for the Treatment of Corneal Endothelial Dysfunction by Restoring Mitochondria‐ER Contacts

Advanced Science, EarlyView.
High glucose triggers corneal endothelial dysfunction by impairing FOXO1‐mediated ITPR1 transcription, leading to disrupted mitochondria‐associated membrane (MAM) integrity and defective ER‐to‐mitochondria Ca2+ transfer. This study develops an innovative viscous DES‐AAV‐Foxo1 delivery system with enhanced transfection efficiency. This non‐invasive gene
Hongran Zhao, Xiaoyu Li, Hongwei Wang, Zongyi Li, Qun Wang, Yangyang Zhang, Xu Jing, Xia Qi, Qingjun Zhou, Shengqian Dou, Lixin Xie   +10 more
wiley   +1 more source