Results 131 to 140 of about 323,640 (268)

Regional Trends in the Opioid Epidemic Using Safety Signals of Drug Abuse and Dependence: A Disproportionality Analysis Using VigiBase. [PDF]

Drugs Real World Outcomes
Suh B, Oh HS, Shin JY, Kim JH.
europepmc   +1 more source

Helicobacter pylori‐Induced Persistent IGF2BP1 Activation Promotes Ferroptosis Resistance in Gastric Tumorigenesis

Advanced Science, EarlyView.
Helicobacter pylori infection induces sustained upregulation of the RNA‐binding protein IGF2BP1 in gastric epithelial cells, establishing a persistent epitranscriptomic program. IGF2BP1 stabilizes SLC7A11 mRNA in an m6A‐dependent manner to suppress ferroptosis and promote epithelial survival under oxidative stress. Pharmacological inhibition of IGF2BP1
Jing Ning, Xin Guan, Xinyu Hao, Jing Zhang, Deyao Li, Ying Xiong, Wenlin Zhang, Xiurui Han, Yanfei Lang, Meiling Zhou, Mengjie Yang, Zhi Huang, Tinghui Qu, Ming Zu, Qiao Meng, Weiwei Fu, Fengmin Lu, Jing Zhang, Xiangmei Chen, Tong Liu, Shigang Ding   +20 more
wiley   +1 more source

Infective Endocarditis in Patients With a History of Intravenous Drug Abuse. [PDF]

Cureus
Bursy M, Dudek A, Szkudlarek W, Linkiewicz J, Lizurej W, Buda A, Kubik M, Bogdanski A, Bogdanska K, Mazur M.   +9 more
europepmc   +1 more source

Palmitoyl Acyltransferase Zdhhc17 Promotes Functional Recovery After Spinal Cord Injury by Targeting the Nuclear Transport Factors Kpna2 and Ipo9

Advanced Science, EarlyView.
In this study, we demonstrate that Zdhhc17, acting as a PAT, suppresses neuronal apoptosis and promotes axon regeneration after injury, thereby enhancing functional recovery following SCI. In this context, Kpna2 and Ipo9 serve as novel palmitoylation substrates of Zdhhc17, whose palmitoylation prevents the injury‐induced degradation of their proteins ...
Meixuan Chen, Huan Chen, Sining Ding, Fan Liu, Xiaofei Zheng, Yuan Wang, Ruitu Tian, Huan Li, Peilin Liu, Le Hu, Bin Liu, Limin Rong, Mangmang Li   +12 more
wiley   +1 more source

Initiating a Life Skills Module to Prevent Drug Abuse Among Indonesian Adolescents Using Social Cognitive Theory. [PDF]

J Multidiscip Healthc
Utami YC, Rinawan FR, Sari P, Mutyara K, Herawati DMD.   +4 more
europepmc   +1 more source

Decoding the Neural Circuit Underlying Context‐Cue Association in Retrieval of Morphine Reward Memory

Advanced Science, EarlyView.
Contextual cues recruit the glutamatergic vCA1–dmPFC pathway to retrieve morphine reward memory by reshaping cell‐type‐specific prefrontal microcircuit activity. Distinct regulation of PV+ and SST+ interneurons defines this hippocampal–prefrontal mechanism.
Zhifeng Shi, Guangying Li, Qian Yang, Rusun Liu, Linghan Gu, Mingmei Wang, John L. Waddington, Fuhai Ji, Xuechu Zhen   +8 more
wiley   +1 more source

NIDA Clinical Trials Network common data elements initiative: advancing big-data addictive-disorders research

Frontiers in Psychiatry, 2015
Udi E Ghitza, Robert E Gore-Langton, Robert eLindblad, Betty eTai   +3 more
doaj   +1 more source

Field survey on warnings to prevent drug abuse when selling over-the-counter drugs at drugstores. [PDF]

Explor Res Clin Soc Pharm
Nagashima K, Nasu H, Sekine Y.
europepmc   +1 more source

Adhesion‐Enhanced Engineered Probiotic for Prolonged Intestinal Retention and Calprotectin‐Responsive IBD Therapy

Advanced Science, EarlyView.
An intelligent engineered probiotic platform is developed for the precision management of inflammatory bowel disease. By integrating surface‐displayed adhesins with an inflammation‐responsive CAT‐SOD‐GPx tripartite fusion system and mucosal repair factors, this programmable system achieves prolonged intestinal retention and multi‐pronged therapy.
Yuxi Wang, Peichao Zhang, Simin Gu, Hongyun Lu, Ningning Jiang, Jiarun Zhao, Enbo Xu, Xiayu Liu, Ying Shi, Qihe Chen   +9 more
wiley   +1 more source

Z-drug abuse and dependence: clinical guideline of the Brazilian Academy of Neurology for diagnosis and management. [PDF]

Arq Neuropsiquiatr
Stelzer FG, Bacelar A, Éckeli AL, Negrão AB, Almeida CMO, Franco CMR, Pires GN, Gitaí LLG, Sobreira-Neto MA, Assis M, Mei PA, Hasan R, Martinez SCG, Marchiori T, Fidalgo TM, Siqueira LL, Poyares D.   +16 more
europepmc   +1 more source