Results 121 to 130 of about 315,545 (267)
Regional Trends in the Opioid Epidemic Using Safety Signals of Drug Abuse and Dependence: A Disproportionality Analysis Using VigiBase. [PDF]
Suh B, Oh HS, Shin JY, Kim JH.
europepmc +1 more source
A Novel Pak1 Activator Ameliorates ER Stress for HFpEF Therapy
Chronic metabolic stress is a major contributor to HFpEF progression. Under prolonged metabolic stress, Pak1 activity becomes impaired, contributing to disrupted ER proteostasis, cardiomyocyte apoptosis, fibrosis, and diastolic dysfunction. Mechanistically, Pak1 overexpression activates the ERK1/2–MNK1–eIF4E signaling axis, promotes translational ...
Honglin Xu +17 more
wiley +1 more source
Infective Endocarditis in Patients With a History of Intravenous Drug Abuse. [PDF]
Bursy M +9 more
europepmc +1 more source
"Skin Popping" and "Shooter's Patch" As Manifestations of Intradermal Drug Abuse. [PDF]
Samynathan A +5 more
europepmc +1 more source
A Small‐Molecule DEPTAC Rescues Cognitive Deficits by Targeted Dephosphorylation of Pathological Tau
TP2 is a fully synthetic small‐molecule dephosphorylation‐targeting chimera that recruits endogenous PP2A‐Bα to Tau, enabling targeted removal of pathological phosphate modifications. In two tauopathy mouse models, systemic TP2 reduces Tau pathology, preserves neuronal and synaptic integrity, improves neuroimmune homeostasis, and rescues cognition ...
Fei Sun +12 more
wiley +1 more source
Initiating a Life Skills Module to Prevent Drug Abuse Among Indonesian Adolescents Using Social Cognitive Theory. [PDF]
Utami YC +4 more
europepmc +1 more source
A bottom‐up, component‐resolved framework combining DSC/TGA, evolved gas analysis, and in situ XRD reveals how decomposition pathways control energy release in partial and micro‐cell configurations. Separator‐free assemblies are dominated by cathode‐O2${\rm O}_2$/anode‐Li reactions, while the separator restricts oxygen transport, reshapes the reaction ...
Ayrton M. Yanyachi +8 more
wiley +1 more source
Field survey on warnings to prevent drug abuse when selling over-the-counter drugs at drugstores. [PDF]
Nagashima K, Nasu H, Sekine Y.
europepmc +1 more source

