Results 111 to 120 of about 962,829 (360)
Advanced Science, EarlyView.Multidrug‐resistant Vibrio infections are rising rapidly and threaten coastal populations worldwide. This study introduces D‐zp37, a chirality‐engineered antimicrobial peptide with exceptional potency against resistant Vibrio species. D‐zp37 kills planktonic cells, blocks mixed‐species biofilms, disrupts essential bacterial stress responses, and shows ...
Ping Zeng +11 more
wiley +1 more source
[The physician, the drug abuser and drug abuse].
Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1990 Drug abusers have a low tolerance for unpleasant and painful emotions and experience a need for chemical relief through use of narcotics, tranquilizers and analgesics. Physicians may show a tendency to comply with their request for such drugs, partly because they give way under pressure (threats, violence) and partly because of their own unconscious ...
openaire +1 more source
Advanced Science, EarlyView.Glaucoma, a major cause of blindness, involves retinal ganglion cell (RGC) degeneration. This study shows growth hormone‐releasing hormone receptor (GHRHR) deficiency preserves RGC survival and restores vision, unlike activation which only aids survival.
Yan Tong +24 more
wiley +1 more source
Gabapentinoid use disorder. Update for clinicians [PDF]
, 2018 Gabapentinoids (gabapentin and pregabalin) are versatile drugs, indicated mainly for epilepsy and neuropathic pain, and have long been viewed as agents with little potential for abuse.
Ann LeQuang, Jo +5 more
core
Loperamide: an emerging drug of abuse and cause of prolonged QTc [PDF]
, 2021 George Whittaker, Joseph Newman
openalex +1 more source
Advanced Science, EarlyView.ANKS1B in the nucleus accumbens plays a critical role in the transition from controlled to escalated cocaine intake. Mechanistically, ANKS1B interacts with CBP to epigenetically suppress FoxO3 through H3K27 acetylation. The ANKS1B‐CBP‐FoxO3 signaling cascade presents a novel theraputic target for the treatment of cocaine addiction.
Liping Yang +15 more
wiley +1 more source
Incidence of Substance Abuse in the Workplace [PDF]
, 2002 A survey of employers' attitudes regarding the prevalence of drugs in the workplace, how employee drug use impacts their firm, and the effectiveness of company policies to treat and prevent employee substance ...
core
Distinct Biotypes of Visual Perception in Major Depressive Disorder
Advanced Science, Volume 13, Issue 31, 4 June 2026.In a discover dataset (272 acute MDD patients), this work identifies a novel depression biotype characterized by impaired visual motion perception, using machine learning clustering. An independent dataset confirms the robustness of this biotype through cross‐validation and demonstrates its generalizability.
Zhuoran Cai +13 more
wiley +1 more source