Results 21 to 30 of about 435,266 (312)
A Fifty-year challenge in managing drug addiction in Malaysia [PDF]
, 2008 The history of substance abuse in Malaysia can be divided into pre- and post-independent era. In pre-independence, the main drug of abuse was opium which was initially consumed by immigrants from China who were introduced by the British ...
Habil, Mohamad Hussain +3 more
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Neuroanatomic differences of the brain in males and females
Анналы клинической и экспериментальной неврологии, 2017 Gender distribution is an important factor in patient cohorts which may influence the results acquired in studies on pathogenesis and treatment of neuropsychiatric disorders.
Anna G. Polunina, Evgeniy A. Bryun
doaj +1 more source
Frontiers in Behavioral Neuroscience, 2019 Nicotine is acknowledged as the key addictive compound of tobacco. Varenicline (Champix® or Chantix®), mainly acting as a partial agonist at the α4β2 nicotinic receptor, is an approved smoking cessation pharmacotherapy, although with efficacy limited to ...
Vernon Garcia-Rivas +13 more
doaj +1 more source
Recent updates on incubation of drug craving: a mini-review [PDF]
, 2015 Cue-induced drug craving progressively increases after prolonged withdrawal from drug self-administration in laboratory animals, a behavioral phenomenon termed 'incubation of drug craving.' Studies over the years have revealed several important neural ...
Abdolahi +39 more
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Are cocaine-seeking “habits” necessary for the development of addiction-like behavior in rats? [PDF]
, 2018 Drug self-administration models of addiction typically require animals to make the same response (e.g., a lever-press or nose-poke) over and over to procure and take drugs.
Fadanelli, Monica +3 more
core +2 more sources
An inevitable wave of prescription drug monitoring programs in the context of prescription opioids: pros, cons and tensions [PDF]
, 2014 BACKGROUND: In an effort to control non-medical use and/or medical abuse of prescription drugs, particularly prescription opioids, electronic prescription drug monitoring programs (PDMP) have been introduced in North-American countries, Australia and ...
Islam, M. Mofizul, McRae, Ian S.
core +2 more sources
κ-Opioid receptor antagonism reverses heroin withdrawal-induced hyperalgesia in male and female rats
Neurobiology of Stress, 2021 Although opioids are potent analgesics, a consequence of chronic opioid use is hyperalgesia during withdrawal, which may contribute to opioid misuse. Dynorphin, the endogenous ligand of κ-opioid receptors (KORs), is upregulated in opioid-dependent rats ...
Renata C.N. Marchette +8 more
doaj +1 more source
Recreational Use of Nitrous Oxide – a Growing Concern in Europe
Emerging Trends in Drugs, Addictions, and HealthIntroduction: Nitrous oxide, commonly known as laughing gas, is used medically as an analgesic and anaesthetic. It has been used recreationally for its brief euphoric effects for over 200 years, however, in the last decade, there has been a large ...
J. De Morais +16 more
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Harm reduction in the Heartland: public knowledge and beliefs about naloxone in Nebraska, USA
Harm Reduction Journal, 2022 Background Opioid-related overdose deaths have been increasing in the United States (U.S.) in the last twenty years, creating a public health challenge.
Allison Schlosser +2 more
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Frontiers in Molecular Neuroscience, 2022 Methamphetamine (MA) abuse results in neurotoxic outcomes, including increased anxiety and depression. Studies have reported an association between MA exposure and anxiety, nonetheless, the underlying mechanism remains elusive.
Fengrong Chen +26 more
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