Results 21 to 30 of about 4,201,815 (397)

Neural Substrates and Circuits of Drug Addiction.

Cold Spring Harbor Perspectives in Medicine, 2020
Drug addiction is a chronic relapsing disorder, and a significant amount of research has been devoted to understand the factors that contribute to the development, loss of control, and persistence of compulsive addictive behaviors.
M. W. Feltenstein, R. See, R. A. Fuchs
semanticscholar   +1 more source

Cocaine Addiction as a Homeostatic Reinforcement Learning Disorder [PDF]

, 2017
Drug addiction implicates both reward learning and homeostatic regulation mechanisms of the brain. This has stimulated 2 partially successful theoretical perspectives on addiction.
Durand, A., Girardeau, P., Gutkin, B., Keramati, M., Serge, A.   +4 more
core   +1 more source

Parameters for Change in Offline Gambling Behavior After the First COVID-19 Lockdown in Germany

Frontiers in Psychology, 2022
IntroductionIn spring 2020, the first nationwide lockdown in response to the spreading COVID-19 pandemic came into effect in Germany. From March to May, gambling venues, casinos, and betting offices were forced to close.
Jens Kalke, Jens Kalke, Christian Schütze, Christian Schütze, Harald Lahusen, Harald Lahusen, Sven Buth, Sven Buth   +7 more
doaj   +1 more source

Smoke, alcohol and drug addiction and female fertility

Reproductive Biology and Endocrinology, 2020
Background Considerable interest has been gathered on the relevant impact of preventable factors, including incorrect lifestyle and unhealthy habits, on female fertility.
C. de Angelis, A. Nardone, F. Garifalos, C. Pivonello, A. Sansone, A. Conforti, C. di Dato, F. Sirico, C. Alviggi, A. Isidori, A. Colao, R. Pivonello   +11 more
semanticscholar   +1 more source

Course and Correlates of Stigma in Patients on Opioid Agonist Treatment: A Prospective Study from an Outpatient Treatment Program in India

Indian Journal of Psychological Medicine, 2022
Background: Individuals with opioid dependence experience stigma and discrimination. Stigma can potentially reduce treatment-seeking and negatively affect treatment outcomes.
Abhishek Ghosh, Fazle Roub, Renjith R. Pillai, Tathagata Mahintamani, Debasish Basu, B.N. Subodh, S.K. Mattoo   +6 more
doaj   +1 more source

Toll-Like Receptor 4 Signaling and Drug Addiction

Frontiers in Pharmacology, 2020
The emphasis of neuronal alterations and adaptations have long been the main focus of the studies of the mechanistic underpinnings of drug addiction. Recent studies have begun to appreciate the role of innate immune system, especially toll-like receptor ...
Ruyan Wu, Jun-Xu Li
semanticscholar   +1 more source

Association between CD4+ T cell counts and gut microbiota and serum cytokines levels in HIV-infected immunological non-responders

BMC Infectious Diseases, 2021
Background CD4+ T cell counts in certain human immunodeficiency virus (HIV)-infected patients called immunological non-responders (INRs) could not return to a normal level even with sustained antiretroviral therapy (ART) because of persistent immune ...
Danfeng Lu, Jian-Bo Zhang, Yue-Xin Wang, Shi-Tao Geng, Zunyue Zhang, Yu Xu, Shao-You Li, Kun-Hua Wang, Yi-Qun Kuang   +8 more
doaj   +1 more source

MicroRNAs and Drug Addiction [PDF]

Frontiers in Genetics, 2013
Drug addiction is considered a disorder of neuroplasticity in brain reward and cognition systems resulting from aberrant activation of gene expression programs in response to prolonged drug consumption. Non-coding RNAs (ncRNAs) are key regulators of almost all aspects of cellular physiology.
Paul J. Kenny, Purva Bali
openaire   +4 more sources

Are cocaine-seeking “habits” necessary for the development of addiction-like behavior in rats? [PDF]

, 2018
Drug self-administration models of addiction typically require animals to make the same response (e.g., a lever-press or nose-poke) over and over to procure and take drugs.
Fadanelli, Monica, Kawa, Alex B., Robinson, Terry E., Singer, Bryan F.   +3 more
core   +2 more sources

Comparative Analysis of Potential Risk Factors for at-Risk Gambling, Problem Gambling and Gambling Disorder among Current Gamblers—Results of the Austrian Representative Survey 2015

Frontiers in Psychology, 2017
Background: The risk of developing a problem gambling behavior is distributed unequally among the population. For example, individuals who report stressful life events, show impairments of mental health or belong to a socio-economically deprived group ...
Sven Buth, Sven Buth, Friedrich M. Wurst, Friedrich M. Wurst, Friedrich M. Wurst, Natasha Thon, Harald Lahusen, Harald Lahusen, Jens Kalke, Jens Kalke   +9 more
doaj   +1 more source