Results 31 to 40 of about 4,201,815 (397)
Detecting a signal in the noise : Monitoring the global spread of novel psychoactive substances using media and other open source information [PDF]
This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no ...
Canadian Community Epidemiology Network On Drug Use+3 more
core +1 more source
Chronic sleep disturbances (CSDs) including insomnia, insufficient sleep time, and poor sleep quality are major public health concerns around the world, especially in developed countries.
Liyang Guo+8 more
doaj +1 more source
Drug addiction may be a goal-directed choice driven by excessive drug value in negative affective states, a habit driven by strong stimulus−response associations, or a compulsion driven by insensitivity to costs imposed on drug seeking. Laboratory animal
L. Hogarth
semanticscholar +1 more source
Nicotine is acknowledged as the key addictive compound of tobacco. Varenicline (Champix® or Chantix®), mainly acting as a partial agonist at the α4β2 nicotinic receptor, is an approved smoking cessation pharmacotherapy, although with efficacy limited to ...
Vernon Garcia-Rivas+13 more
doaj +1 more source
Drug Addiction: Updating Actions to Habits to Compulsions Ten Years On.
A decade ago, we hypothesized that drug addiction can be viewed as a transition from voluntary, recreational drug use to compulsive drug-seeking habits, neurally underpinned by a transition from prefrontal cortical to striatal control over drug seeking ...
B. Everitt, T. Robbins
semanticscholar +1 more source
Incentive learning underlying cocaine relapse requires mGluR5 receptors located on dopamine D1 receptor-expressing neurons [PDF]
Understanding the psychobiological basis of relapse remains a challenge in developing therapies for drug addiction. Relapse in cocaine addiction often occurs following exposure to environmental stimuli previously associated with drug taking.
Bilbao, Ainhoa+11 more
core +2 more sources
Neuroanatomic differences of the brain in males and females
Gender distribution is an important factor in patient cohorts which may influence the results acquired in studies on pathogenesis and treatment of neuropsychiatric disorders.
Anna G. Polunina, Evgeniy A. Bryun
doaj +1 more source
Modafinil dependence: A case with attention-deficit/hyperactivity disorder [PDF]
Modafinil is generally known as a drug with low addiction potential. There are few case reports in the literature demonstrating that Modafinil, stated being capable of diminishing symptoms of attention deficit/hyperactivity disorder (ADHD), causes ...
Alaçam, Hüseyin+4 more
core +1 more source
A Fifty-year challenge in managing drug addiction in Malaysia [PDF]
The history of substance abuse in Malaysia can be divided into pre- and post-independent era. In pre-independence, the main drug of abuse was opium which was initially consumed by immigrants from China who were introduced by the British ...
Habil, Mohamad Hussain+3 more
core +1 more source