Results 61 to 70 of about 4,201,815 (397)
FEBS Letters, EarlyView.Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke +2 more
wiley +1 more source
Hijacking translation in addiction. [PDF]
, 2016 Two studies suggest that the reduced activity of a translation initiation factor called eIF2α might be partly responsible for the increased risk of drug addiction seen in ...
Izquierdo, Alicia, Silva, Alcino J
core +1 more source
Annals of General Psychiatry, 2018 Background In the Gambling Disorder (GD), there is no exogenous drug administration that acts as the central core of the traditional meaning of addiction. A specific psychopathology of Substance Use Disorders has been proposed recently.
Angelo G. I. Maremmani +6 more
doaj +1 more source
Ketogenic diet: a potential adjunctive treatment for substance use disorders
Frontiers in Nutrition, 2023 Substance use disorders (SUD) can lead to serious health problems, and there is a great interest in developing new treatment methods to alleviate the impact of substance abuse.
Deshenyue Kong +16 more
doaj +1 more source
Pathways Relating the Neurobiology of Attachment to Drug Addiction
Frontiers in Psychiatry, 2019 Substance use disorders constitute a significant public health problem in North America and worldwide. Specifically, substance addictions in women during pregnancy or in the postpartum period have adverse effects not only on the mother, but also on ...
Lane Strathearn +7 more
semanticscholar +1 more source
Autophagy in cancer and protein conformational disorders
FEBS Letters, EarlyView.Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley +1 more source
Novel psychoactive substance use by mental health service consumers: an online survey of inpatient health professionals’ views and experiences [PDF]
, 2017 Purpose: There is evidence that novel psychoactive substances (NPS) are commonly used by people with severe mental illness. The aim of the study was to undertake a scoping survey to explore inpatient mental health workers' perceptions of NPS use by ...
Clinical Guidelines on Drug Misuse and Dependence Update 2017 Independent Expert Working Group +4 more
core +1 more source
FEBS Letters, EarlyView.The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp +5 more
wiley +1 more source
Epigenetic Priming in Drug Addiction
Cold Spring Harbor Symposia on Quantitative Biology, 2019 Drug addiction is a chronic relapsing brain disorder that is characterized by compulsive drug seeking and continued use despite negative outcomes. Current pharmacological therapies target neuronal receptors or transporters upon which drugs of abuse act ...
Philipp Mews, D. Walker, E. Nestler
semanticscholar +1 more source