Results 1 to 10 of about 7,637,675 (330)

Intracerebroventricular drug administration

open access: yesTranslational and Clinical Pharmacology, 2017
Among the various routes of drug administration, perhaps the least studied is intracerebroventricular (ICV) administration. This route has been shown to be particularly useful in administering to the central nervous system (CNS) drugs that do not cross ...
A. Atkinson
semanticscholar   +4 more sources

Reduced efficacy of praziquantel against Schistosoma mansoni associated with multiple-rounds of mass drug administration [PDF]

open access: yesClinical Infectious Diseases, 2016
The efficacy of praziquantel against Schistosoma mansoni was significantly lower in Ugandan schools that had received more prior rounds of mass drug administration, as determined by fitting a statistical model to parasite egg counts before and after ...
Edridah M. Tukahebwa   +7 more
core   +3 more sources

US Food and Drug Administration Accelerated Approval Program for Nononcology Drug Indications Between 1992 and 2018

open access: yesJAMA Network Open, 2022
This cohort study evaluates how the US Food and Drug Administration (FDA) accelerated approval program has been used for nononcology drugs over a period of 26 years.
Kenji Omae   +3 more
semanticscholar   +1 more source

Comparison of Amitriptyline and US Food and Drug Administration–Approved Treatments for Fibromyalgia

open access: yesJAMA Network Open, 2022
This systematic review and network meta-analysis compares amitriptyline with Food and Drug Administration–approved treatments for fibromyalgia related to sleep, fatigue, and health-related quality of life outcomes.
Hussein M Farag   +5 more
semanticscholar   +1 more source

The contribution of smoking-attributable mortality to differences in mortality and life expectancy among US African-American and white adults, 2000-2019

open access: yesDemographic Research, 2022
Background: The role of smoking in racial disparities in mortality and life expectancy in the United States has been examined previously, but up-to-date estimates are generally unavailable, even though smoking prevalence has declined in recent decades.
Brian L. Rostron   +5 more
doaj   +1 more source

Anticancer Drugs Approved by the US Food and Drug Administration From 2009 to 2020 According to Their Mechanism of Action

open access: yesJAMA Network Open, 2021
Key Points Question How often are anticancer drugs approved based on a new mechanism of action? Findings In this cross-sectional study of 332 US Food and Drug Administration–approved anticancer drugs from 2009 to 2020, 16% of approvals were based on a ...
T. Olivier, A. Haslam, V. Prasad
semanticscholar   +1 more source

Food and Drug Administration

open access: yesDefinitions, 2020
The Food and Drug Administration is responsible for maintaining a national program to protect the public health from unnecessary and harmful radiation emitted by radiation products.
Arif Subhan
semanticscholar   +1 more source

Patterns of Routes of Administration and Drug Tampering for Nonmedical Opioid Consumption: Data Mining and Content Analysis of Reddit Discussions [PDF]

open access: yesJ Med Internet Res 2021;23(1):e21212, 2021
The complex unfolding of the US opioid epidemic in the last 20 years has been the subject of a large body of medical and pharmacological research, and it has sparked a multidisciplinary discussion on how to implement interventions and policies to effectively control its impact on public health.
arxiv   +1 more source

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