Preclinical Determinants of Drug Choice under Concurrent Schedules of Drug Self-Administration [PDF]
Advances in Pharmacological Sciences, 2012 Drug self-administration procedures have played a critical role in the experimental analysis of psychoactive compounds, such as cocaine, for over 50 years. While there are numerous permutations of this procedure, this paper will specifically focus on choice procedures using concurrent schedules of intravenous drug self-administration.
Banks, Matthew L., Negus, S. Stevens
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Online scheduling using a fixed template: the case of outpatient chemotherapy drug administration
Health Care Management Science, 2022 AbstractIn this paper, we use a fixed template of slots for the online scheduling of appointments. The template is a link between planning the service capacity at a tactical level and online scheduling at an operational level. We develop a detailed heuristic for the case of drug administration appointments in outpatient chemotherapy.
Alireza F. Hesaraki +2 more
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Random-ratio schedules produce greater demand for i.v. drug administration than fixed-ratio schedules in rhesus monkeys [PDF]
Psychopharmacology, 2014 Organisms emit more responses when food is provided according to random as compared with fixed schedules of reinforcement. Similarly, many human behaviors deemed compulsive are maintained on variable schedules (e.g., gambling). If greater amounts of behavior are maintained by drugs of abuse when earned according to variably reinforced schedules, this ...
Carla H, Lagorio, Gail, Winger
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Nicotine and cocaine self-administration using a multiple schedule of intravenous drug and sucrose reinforcement in rats [PDF]
Behavioural Pharmacology, 2010 There appears to be a relatively narrow range of contingencies in which intravenous (i.v) infusions of nicotine will maintain responding in rats. The schedule of reinforcement typically used when investigating i.v. nicotine self-administration is a simple fixed-ratio (FR) schedule.
Dustin J, Stairs +2 more
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The effects of dose, route of administration, drug scheduling and MDR-1 gene transfer on the genotoxicity of etoposide in bone marrow [PDF]
Leukemia, 2000 We have used the bone marrow micronucleus assay (BMMN) as a measure of clastogenicity, in response to etoposide exposure in murine bone marrow. Oral delivery of etoposide resulted in a reduced number of micronucleated polychromatic erythrocytes (MPE) relative to the same dose delivered intraperitoneally (P < 0.001).
S D, Turner +7 more
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The FASEB Journal, 2015 As many as 90% of cocaine abusers also drink ethanol (EtOH), suggesting that EtOH enhances sensitivity to the reinforcing effects of cocaine. However, little is known about the interaction of these drugs. In the present studies we determined the effects of acute i.v.
Paul Czoty +2 more
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Intranasal cocaine self-administration in male mice. [PDF]
Nat CommunErickson KR +9 more
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Introducing personalized patient care in overactive bladder management using the MedRing OAB system for intravaginal oxybutynin administration. [PDF]
Drug DelivPeltenburg SI +6 more
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Investigation on Administration Schedule Practice of Hypnotic Drugs of Outpatients.
Japanese Journal of Hospital Pharmacy, 1992 KENZO YONEZAWA +6 more
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Real-world data on the abuse potential of medications for the treatment of insomnia: a disproportionality analysis of the FAERS database. [PDF]
Front PharmacolSaskin P +7 more
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