Results 11 to 20 of about 152,098 (264)

Online scheduling using a fixed template: the case of outpatient chemotherapy drug administration

Health Care Management Science, 2022
AbstractIn this paper, we use a fixed template of slots for the online scheduling of appointments. The template is a link between planning the service capacity at a tactical level and online scheduling at an operational level. We develop a detailed heuristic for the case of drug administration appointments in outpatient chemotherapy.
Alireza F. Hesaraki, Nico P. Dellaert, Ton de Kok   +2 more
openaire   +4 more sources

The Clinical Efficacy of Multidose Oritavancin: A Systematic Review

Antibiotics, 2023
Oritavancin (ORI) is a semisynthetic lipoglycopeptide approved as a single 1200 mg dose intravenous infusion for the treatment of acute bacterial skin and skin structure infections (ABSSSIs) caused by Gram-positive organisms in adults.
Giammarco Baiardi, Michela Cameran Caviglia, Fabio Piras, Fabio Sacco, Roberta Prinapori, Maria Luisa Cristina, Francesca Mattioli, Marina Sartini, Emanuele Pontali   +8 more
doaj   +1 more source

Targeted drug delivery by gemtuzumab ozogamicin: mechanism-based mathematical model for treatment strategy improvement and therapy individualization. [PDF]

PLoS ONE, 2011
Gemtuzumab ozogamicin (GO) is a chemotherapy-conjugated anti-CD33 monoclonal antibody effective in some patients with acute myeloid leukemia (AML). The optimal treatment schedule and optimal timing of GO administration relative to other agents remains ...
Eva Jager, Vincent H J van der Velden, Jeroen G te Marvelde, Roland B Walter, Zvia Agur, Vladimir Vainstein   +5 more
doaj   +1 more source

Cost-minimization analysis of individually tailored or fixed-scheduled rituximab maintenance therapy for antineutrophil-cytoplasm antibody associated vasculitides [PDF]

Farmacia Hospitalaria, 2020
Objective: Patients included in MAINRITSAN2 trial received either an individually tailored or a fixed-schedule therapy with rituximab as maintenance treatment of antineutrophil cytoplasm antibody associated vasculitides.
Ana Belén Guisado-Gil, Marina Muñoz-Burgos, Ana Ortega-Eslava, Francisco Javier García-Hernández, Bernardo Santos-Ramos   +4 more
doaj   +1 more source

Sequential dose-dense single agent chemotherapy for locally advanced breast cancer [PDF]

Archive of Oncology, 2003
Chemotherapy of breast cancer is still the area of intensive research. Based on mathematical model of tumor cell growth kinetics, articulated by Larry Norton, novel concept of chemotherapy in breast cancer was launched and it implies dose-densification ...
Vrbić Svetislav, Pejčić Ivica, Filipović Slađana, Radić Stojan S.   +3 more
doaj   +1 more source

Abordaje terapéutico de la otitis media aguda en atención primaria de un área urbana. Evaluación de la prescripción diferida de antibióticos

Anales de Pediatría, 2022
Resumen: Introducción: La otitis media aguda (OMA) es una de las causas más frecuentes de consulta y prescripción antibiótica en pediatría. El objetivo de este trabajo es valorar la prescripción antibiótica diferida en OMA en pediatría en atención ...
María García Ventura, César García Vera, Juan Ruiz-Canela Cáceres   +2 more
doaj   +1 more source

Prevalence, reasons and factors associated with intentional nonadherence to prescribed medications: a population-based study [PDF]

Revista Brasileira de Epidemiologia
Objective: To evaluate the frequency, reasons and factors associated with intentional nonadherence to drug therapy. Methods: A population-based cross-sectional study was conducted with data from the National Survey on Access, Use and Promotion of ...
Tatiana da Silva Sempé, Emilia da Silva Pons, Tatiane da Silva Dal Pizzol, Daniela Riva Knauth, Sotero Serrate Mengue   +4 more
doaj   +1 more source

Random-ratio schedules produce greater demand for i.v. drug administration than fixed-ratio schedules in rhesus monkeys [PDF]

Psychopharmacology, 2014
Organisms emit more responses when food is provided according to random as compared with fixed schedules of reinforcement. Similarly, many human behaviors deemed compulsive are maintained on variable schedules (e.g., gambling). If greater amounts of behavior are maintained by drugs of abuse when earned according to variably reinforced schedules, this ...
Carla H, Lagorio, Gail, Winger
openaire   +2 more sources

Deep brain stimulation of the nucleus accumbens core but not shell reduces motivational components of heroin taking and seeking in rats

Brain and Neuroscience Advances, 2017
Background: Deep brain stimulation is explored as a new intervention for treatment-resistant substance use dependence. A candidate brain region is the nucleus accumbens, due to its involvement in reward and motivation. This study aimed to explore effects
Maria C. Schippers, Mathijs Gaastra, Tanja Mesman, Dustin Schetters, Yvar van Mourik, Damiaan Denys, Tommy Pattij, Taco J. De Vries   +7 more
doaj   +1 more source

Sex and Feeding Status Differently Affect Natural Reward Seeking Behavior in Olfactory Bulbectomized Rats

Frontiers in Behavioral Neuroscience, 2018
Substance abuse and depression are common psychiatric disorders with a high rate of comorbidity. Both conditions affect differently men and women and preclinical research has showed many sex differences in drug addiction and depression.
Jana Ruda-Kucerova, Mary Tresa Zanda, Petra Amchova, Walter Fratta, Walter Fratta, Liana Fattore, Liana Fattore   +6 more
doaj   +1 more source