Results 261 to 270 of about 1,034,896 (346)

United States healthcare encounters for poisoning involving cannabis relative to other substances. [PDF]

Am J Drug Alcohol Abuse
Conrad SW, Greene CR, Dal Pan G, Callahan CL, Meyer TE, Radin RG.   +5 more
europepmc   +1 more source

Use of the GSK MenACWY-CRM/MenB-4C Pentavalent Meningococcal Vaccine Among Persons Aged ≥10 Years: Recommendations of the Advisory Committee on Immunization Practices - United States, 2025. [PDF]

MMWR Morb Mortal Wkly Rep
Amin AB, Collins JP, Dong X, Leidner AJ, Loehr J, Moser CA, McNamara LA.   +6 more
europepmc   +1 more source

First-in-human phase 1 study of RO7119929, an oral TLR7 agonist prodrug, in patients with advanced primary or metastatic liver cancers. [PDF]

J Immunother Cancer
Yoo C, Fabregat-Franco C, Lin CC, Qvortrup C, Oh DY, Yau T, Kim HD, Castet F, Ponz Sarvise M, Hsu C, Rohrberg KS, Lichtenegger FS, Franjkovic I, Kratochwil NA, Bessa J, Rossmann E, Schwalie PC, Rieder N, Pöschinger T, Sie CG, Dettling S, Schlenker R, Jiang T, Dai C, Yun H, Hall E, Yeo Te-Ying A, Hoves S, Cannarile MA, Schiff C, Sangro B.   +30 more
europepmc   +1 more source

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Drug Administration Schedules

American Journal of Psychiatry, 1969
Common current practice is to prescribe psychotropic drugs so that a specified daily amount is administered in equally divided doses on a three to six times a day schedule. The authors contend that this procedure rests on no valid scientific basis.
A, Dimascio, R I, Shader
openaire   +4 more sources

Schedule-induced drug self-administration

1993
Publisher Summary This chapter describes schedule-induced drug self-administration. The characteristics of schedule-induced behavior bear some similarities to the behavioral features of drug abuse. Both are chronically excessive sorts of behavior with powerful motivational efficacies.
J. Falk
openaire   +2 more sources

Acquisition of nicotine self-administration in rats: the effects of dose, feeding schedule, and drug contingency

Psychopharmacology, 1998
The studies presented here were designed to further clarify the nature of nicotine self-administration (SA) based on a limited access model in which rats are food restricted, receive operant training using food reinforcement, and are then tested in daily 1-h drug sessions.
E C, Donny, A R, Caggiula, M M, Mielke, K S, Jacobs, C, Rose, A F, Sved   +5 more
openaire   +3 more sources

Pre-exposure of rats to amphetamine sensitizes self-administration of this drug under a progressive ratio schedule

Psychopharmacology, 1998
Two groups of male rats were tested to determine whether pre-exposure to d-amphetamine would enhance the motivation to self-administer the drug under a progressive ratio schedule of reinforcement. In the first phase of the experiment, one group of rats received d-amphetamine (2 mg/kg IP), while a second group received saline on alternate days for a ...
A, Mendrek, C D, Blaha, A G, Phillips
openaire   +3 more sources

Measures of cocaine-seeking behavior using a multiple schedule of food and drug self-administration in rats

Drug and Alcohol Dependence, 1995
Animal models of human drug abuse measuring (i) cocaine-seeking behavior maintained by primary or secondary reinforcers, (ii) the time to extinction of cocaine-seeking behavior, and (iii) following extinction, reinstatement of operant responding resulting in presentation of a cocaine-associated stimulus were developed in rats.
R, Weissenborn, M, Yackey, G F, Koob, F, Weiss   +3 more
openaire   +3 more sources