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Azlocillin pharmacokinetics was studied after a single intravenous injection of the antibiotic in a dose of 4 g in 20 patients in critical state. To elucidate the causes of significant individual variability of the antibiotic pharmacokinetics observed in the patients, multiple correlation analysis of the main pharmacokinetic parameters i. e.
A A, Firsov +3 more
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Large dose of Yang-restoring herb medicines. (Radix Codonopsis Pilosulae, Astragalus membranaceus, Radix Aconiti Praeparata, Epimedium brevicornum, Cortex Cinnamomi and Herba Cistanchis) may exert an unfavorable effect on normal rats, i. e. natural weight gain reduced (P less than 0.01), serum T3 decreased (P less than 0.05), rT3, TRH levels raised (P ...
M D, Chen, A K, Kuang, J L, Chen
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Drug self-administration studies
Behavioural Pharmacology, 2013Relative reinforcing effects of different ethanol and different cocaine doses were studied under concurrent independent fixed-ratio (FR) schedules and concurrent nonindependent FR schedules with rhesus monkeys. Nonindependent FR schedules differed from independent FR schedules in that responses on either side counted towards the FR requirements of two ...
Richard A, Meisch, Thomas H, Gomez
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This is a final rule of the Deputy Administrator of the Drug Enforcement Administration (DEA) transferring a drug between schedules of the Controlled Substances Act (CSA) pursuant to 21 U.S.C. 811. With the issuance of this final rule, the Deputy Administrator transfers from schedule II to schedule III of the CSA the drug containing synthetic ...
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Effects of drugs on schedule-controlled behavior in rats during chronic haloperidol administration.
The Journal of Pharmacology and Experimental Therapeutics, 1985Dose-response curves for haloperidol, phencyclidine, morphine, meperidine and cimetidine were determined in rats trained under a multiple fixed-ratio 30, fixed-interval 5-min schedule of reinforcement. Haloperidol, morphine, meperidine and cimetidine decreased both fixed-ratio and fixed-interval rates of responding.
S K, Rastogi, D E, McMillan
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Psychopharmacology, 1998
The studies presented here were designed to further clarify the nature of nicotine self-administration (SA) based on a limited access model in which rats are food restricted, receive operant training using food reinforcement, and are then tested in daily 1-h drug sessions.
E C, Donny +5 more
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The studies presented here were designed to further clarify the nature of nicotine self-administration (SA) based on a limited access model in which rats are food restricted, receive operant training using food reinforcement, and are then tested in daily 1-h drug sessions.
E C, Donny +5 more
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Schedule-induced drug self-administration
1993Publisher Summary This chapter describes schedule-induced drug self-administration. The characteristics of schedule-induced behavior bear some similarities to the behavioral features of drug abuse. Both are chronically excessive sorts of behavior with powerful motivational efficacies.
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Естественные и технические науки, 2020
В данной статье рассматриваются результаты исследования по использованию гормональных препаратов в определённом режиме с целью контроля и управления репродуктивными функциями млекопитающих при искусственном осеменении на примере кроликов. The article discusses the results of hormonal drugs ...
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В данной статье рассматриваются результаты исследования по использованию гормональных препаратов в определённом режиме с целью контроля и управления репродуктивными функциями млекопитающих при искусственном осеменении на примере кроликов. The article discusses the results of hormonal drugs ...
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