Results 21 to 30 of about 1,034,896 (346)

The Clinical Efficacy of Multidose Oritavancin: A Systematic Review

open access: yesAntibiotics, 2023
Oritavancin (ORI) is a semisynthetic lipoglycopeptide approved as a single 1200 mg dose intravenous infusion for the treatment of acute bacterial skin and skin structure infections (ABSSSIs) caused by Gram-positive organisms in adults.
Giammarco Baiardi   +8 more
doaj   +1 more source

Acute drug effects on habitual and non-habitual responding in crossed high alcohol preferring mice [PDF]

open access: yes, 2018
RATIONALE: Drug reward plays a central role in acquiring drug-seeking behavior. However, subjects may continue using drugs despite negative consequences because self-administration becomes habitual, and divorced from outcome values. Although a history
Grahame, Nicholas J., Houck, Christa A.
core   +1 more source

Online scheduling using a fixed template: the case of outpatient chemotherapy drug administration

open access: yesHealth Care Management Science, 2022
AbstractIn this paper, we use a fixed template of slots for the online scheduling of appointments. The template is a link between planning the service capacity at a tactical level and online scheduling at an operational level. We develop a detailed heuristic for the case of drug administration appointments in outpatient chemotherapy.
Alireza F. Hesaraki   +2 more
openaire   +5 more sources

Fentanyl‐related substance scheduling as an effective drug control strategy

open access: yesJournal of Forensic Sciences, 2021
Fentanyl is now the primary driver of the current opioid crisis. Fentanyl and its analogues are subject to the Controlled Substances Act of 1970, the Controlled Substances Analogue Enforcement Act of 1986 (Federal Analogue Act), state laws, international
V. Weedn   +4 more
semanticscholar   +1 more source

Targeted drug delivery by gemtuzumab ozogamicin: mechanism-based mathematical model for treatment strategy improvement and therapy individualization. [PDF]

open access: yesPLoS ONE, 2011
Gemtuzumab ozogamicin (GO) is a chemotherapy-conjugated anti-CD33 monoclonal antibody effective in some patients with acute myeloid leukemia (AML). The optimal treatment schedule and optimal timing of GO administration relative to other agents remains ...
Eva Jager   +5 more
doaj   +1 more source

Mathematical and computational models of drug transport in tumours [PDF]

open access: yes, 2014
The ability to predict how far a drug will penetrate into the tumour microenvironment within its pharmacokinetic (PK) lifespan would provide valuable information about therapeutic response.
Groh, C.M.   +8 more
core   +1 more source

Medication regimen complexity in adults and the elderly in a primary healthcare setting: determination of high and low complexities

open access: yesPharmacy Practice, 2015
Background: The complexity of a medication regimen is related to the multiple characteristics of the prescribed regimen and can negatively influence the health outcomes of patients.
Ferreira JM, Galato D, Melo AC
doaj   +1 more source

Sequential dose-dense single agent chemotherapy for locally advanced breast cancer [PDF]

open access: yesArchive of Oncology, 2003
Chemotherapy of breast cancer is still the area of intensive research. Based on mathematical model of tumor cell growth kinetics, articulated by Larry Norton, novel concept of chemotherapy in breast cancer was launched and it implies dose-densification ...
Vrbić Svetislav   +3 more
doaj   +1 more source

Cost-minimization analysis of individually tailored or fixed-scheduled rituximab maintenance therapy for antineutrophil-cytoplasm antibody associated vasculitides [PDF]

open access: yesFarmacia Hospitalaria, 2020
Objective: Patients included in MAINRITSAN2 trial received either an individually tailored or a fixed-schedule therapy with rituximab as maintenance treatment of antineutrophil cytoplasm antibody associated vasculitides.
Ana Belén Guisado-Gil   +4 more
doaj   +1 more source

Abordaje terapéutico de la otitis media aguda en atención primaria de un área urbana. Evaluación de la prescripción diferida de antibióticos

open access: yesAnales de Pediatría, 2022
Resumen: Introducción: La otitis media aguda (OMA) es una de las causas más frecuentes de consulta y prescripción antibiótica en pediatría. El objetivo de este trabajo es valorar la prescripción antibiótica diferida en OMA en pediatría en atención ...
María García Ventura   +2 more
doaj   +1 more source

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