The Clinical Efficacy of Multidose Oritavancin: A Systematic Review
Oritavancin (ORI) is a semisynthetic lipoglycopeptide approved as a single 1200 mg dose intravenous infusion for the treatment of acute bacterial skin and skin structure infections (ABSSSIs) caused by Gram-positive organisms in adults.
Giammarco Baiardi +8 more
doaj +1 more source
Acute drug effects on habitual and non-habitual responding in crossed high alcohol preferring mice [PDF]
RATIONALE: Drug reward plays a central role in acquiring drug-seeking behavior. However, subjects may continue using drugs despite negative consequences because self-administration becomes habitual, and divorced from outcome values. Although a history
Grahame, Nicholas J., Houck, Christa A.
core +1 more source
Online scheduling using a fixed template: the case of outpatient chemotherapy drug administration
AbstractIn this paper, we use a fixed template of slots for the online scheduling of appointments. The template is a link between planning the service capacity at a tactical level and online scheduling at an operational level. We develop a detailed heuristic for the case of drug administration appointments in outpatient chemotherapy.
Alireza F. Hesaraki +2 more
openaire +5 more sources
Fentanyl‐related substance scheduling as an effective drug control strategy
Fentanyl is now the primary driver of the current opioid crisis. Fentanyl and its analogues are subject to the Controlled Substances Act of 1970, the Controlled Substances Analogue Enforcement Act of 1986 (Federal Analogue Act), state laws, international
V. Weedn +4 more
semanticscholar +1 more source
Targeted drug delivery by gemtuzumab ozogamicin: mechanism-based mathematical model for treatment strategy improvement and therapy individualization. [PDF]
Gemtuzumab ozogamicin (GO) is a chemotherapy-conjugated anti-CD33 monoclonal antibody effective in some patients with acute myeloid leukemia (AML). The optimal treatment schedule and optimal timing of GO administration relative to other agents remains ...
Eva Jager +5 more
doaj +1 more source
Mathematical and computational models of drug transport in tumours [PDF]
The ability to predict how far a drug will penetrate into the tumour microenvironment within its pharmacokinetic (PK) lifespan would provide valuable information about therapeutic response.
Groh, C.M. +8 more
core +1 more source
Background: The complexity of a medication regimen is related to the multiple characteristics of the prescribed regimen and can negatively influence the health outcomes of patients.
Ferreira JM, Galato D, Melo AC
doaj +1 more source
Sequential dose-dense single agent chemotherapy for locally advanced breast cancer [PDF]
Chemotherapy of breast cancer is still the area of intensive research. Based on mathematical model of tumor cell growth kinetics, articulated by Larry Norton, novel concept of chemotherapy in breast cancer was launched and it implies dose-densification ...
Vrbić Svetislav +3 more
doaj +1 more source
Cost-minimization analysis of individually tailored or fixed-scheduled rituximab maintenance therapy for antineutrophil-cytoplasm antibody associated vasculitides [PDF]
Objective: Patients included in MAINRITSAN2 trial received either an individually tailored or a fixed-schedule therapy with rituximab as maintenance treatment of antineutrophil cytoplasm antibody associated vasculitides.
Ana Belén Guisado-Gil +4 more
doaj +1 more source
Resumen: Introducción: La otitis media aguda (OMA) es una de las causas más frecuentes de consulta y prescripción antibiótica en pediatría. El objetivo de este trabajo es valorar la prescripción antibiótica diferida en OMA en pediatría en atención ...
María García Ventura +2 more
doaj +1 more source

