Results 121 to 130 of about 776,039 (330)
DRUG LAG FOR ANTIMICROBIAL AGENTS: COMPARISON OF THE US, EU AND INDIA APPROVALS
National Journal of Medical Research, 2012 Background: Antimicrobial resistance is a global problem and the need for new antimicrobial agents is greater in both developed and developing nations.
Bhaven C Kataria +2 more
doaj
Drug approval prediction based on the discrepancy in gene perturbation effects between cells and humans. [PDF]
EBioMedicine, 2023 Park M, Kim D, Kim I, Im SH, Kim S.
europepmc +1 more source
Molecular Oncology, EarlyView.This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini +10 more
wiley +1 more source
Uniqueness of radiomic features in non‐small cell lung cancer
Journal of Applied Clinical Medical Physics, Volume 23, Issue 12, December 2022., 2022 Abstract Purpose The uniqueness of radiomic features, combined with their reproducibility, determines the reliability of radiomic studies. This study is to test the hypothesis that radiomic features extracted from a defined region of interest (ROI) are unique to the underlying structure (e.g., tumor). Approach Two cohorts of non‐small cell lung cancer (
Gary Ge, Jie Zhang
wiley +1 more source
Fast Methods for Drug Approval: Research Perspectives for Pandemic Preparedness. [PDF]
Int J Environ Res Public Health, 2023 Abdin AY, De Pretis F, Landes J.
europepmc +1 more source
Pfizer accused of testing new drug without ethical approval [PDF]
, 2001 J. Wise
openalex +1 more source
The roles and applications of extracellular vesicles in cancer
Molecular Oncology, EarlyView.Extracellular vesicles (EVs) are minute versions of cells limited by a lipid bilayer containing cytoplasm from the cell that releases them, but without a nucleus and thus unable to self‐reproduce. EVs contain multiple molecules (proteins, lipids, glycans, and nucleic acids) they can induce complex responses in cells.
Clotilde Théry, Daniel Louvard
wiley +1 more source
A small footprint couch‐top support device for image‐guided radiotherapy of heavy patients
Journal of Applied Clinical Medical Physics, Volume 23, Issue 12, December 2022., 2022 Abstract Purpose Patients with body weights close to or above 400 lbs present unique challenges in radiation therapy since the weight limit of most treatment couches decreases as the couch‐top extends toward the treatment gantry. The purpose of this work was to develop a small footprint couch‐top support platform to safely perform image‐guided ...
Huixiao Chen +5 more
wiley +1 more source
Current OncologyIntroduction: Advancements in oncology have revolutionized cancer treatment, with new drugs being approved at different rates worldwide. Our objective was to evaluate the approval of new oncological drugs for solid tumors by the Food and Drug ...
Rafael Balsini Barreto +2 more
doaj +1 more source