Results 11 to 20 of about 578,551 (263)
Background Mitochondrial transcription factor A (TFAM) is a transcription factor that maintains mitochondrial DNA (mtDNA) stabilization and initiates mtDNA replication.
Yu Liu +17 more
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Human-ether-a-go-go-related channel (hERG1) is the pore-forming domain of the delayed rectifier K+ channel in the heart which underlies the IKr current.
Meruyert Kudaibergenova +7 more
doaj +1 more source
CCL5/CCR5 axis in human diseases and related treatments
To defense harmful stimuli or maintain the immune homeostasis, the body produces and recruits a superfamily of cytokines such as interleukins, interferons, chemokines etc. Among them, chemokines act as crucial regulators in defense systems.
Zhen Zeng +3 more
doaj +1 more source
Application of Baculovirus Expression Vector System (BEVS) in Vaccine Development
Vaccination is one of the most effective strategies to control epidemics. With the deepening of people’s awareness of vaccination, there is a high demand for vaccination.
Qiaonan Hong +3 more
doaj +1 more source
Neuromuscular blocking drugs in anaesthesia [PDF]
Whenever NMBD’s have been used during anaes-thesia attempts should be made to antagonize them if any TOF fade is visible. Reversal may be attempted with an anticholinesterase, either neostigmine 2.5mg·70kg-1 or edrophonium 35 mg · 70 kg-1 mixed with either glycopyrrolate or atropine. The dose may be repeated ten minutes later if recovery of respiration
F, Donati, J C, Bevan, D R, Bevan
openaire +2 more sources
Antifungal Resistance Analysis of Environmental Isolates of Aspergillus in North India
Triazoles are the major group of antifungals for treating Aspergillus infections. The morbidity and mortality associated with these infections is high and rate of treatment failure is more in patients infected with azole resistant Aspergillus.
Shanu Hoda +4 more
doaj +1 more source
An Update on the Structure of hERG
The human voltage-sensitive K+ channel hERG plays a fundamental role in cardiac action potential repolarization, effectively controlling the QT interval of the electrocardiogram.
Andrew Butler +4 more
doaj +1 more source
Clinical limitations and drug-resistance are the basis of the search for new antifungal therapeutics against biofilm forming pathogen Aspergillus fumigatus.
Shanu Hoda +5 more
doaj +1 more source
Recently, the major challenge in treating osteosarcoma patients is the metastatic disease, most commonly in the lungs. However, the underlying mechanism of recurrence and metastasis of osteosarcoma after surgical resection of primary tumor remains ...
Fan Tang +12 more
doaj +1 more source
Optimization of an In silico Cardiac Cell Model for Proarrhythmia Risk Assessment
Drug-induced Torsade-de-Pointes (TdP) has been responsible for the withdrawal of many drugs from the market and is therefore of major concern to global regulatory agencies and the pharmaceutical industry.
Sara Dutta +9 more
doaj +1 more source

