A Simpler Route for Making Nitrogen-Alkene Rings [PDF]
, 2014 A common nitrogen building block used in many natural product and drug syntheses can now be made in its unprotected form in a single step.
Aggarwal, Varinder K., Turkmen, Yunus
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Optimization of an In silico Cardiac Cell Model for Proarrhythmia Risk Assessment
Frontiers in Physiology, 2017 Drug-induced Torsade-de-Pointes (TdP) has been responsible for the withdrawal of many drugs from the market and is therefore of major concern to global regulatory agencies and the pharmaceutical industry.
Sara Dutta +9 more
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Journal of Pharmaceutical Analysis, 2013 An rp-hplc method for the simultaneous determination of Ramipril (RP) and Amlodipine (AL) in tablets was developed and validated by Chinese Pharmacopoeia 2010. The linearity of the proposed method was investigated in the range of 0.01â0.25Â mg/mL (r2=0.
Shi-Ying Dai +3 more
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Neurological complications and infection mechanism of SARS-COV-2
Signal Transduction and Targeted Therapy, 2021 Currently, SARS-CoV-2 has caused a global pandemic and threatened many lives. Although SARS-CoV-2 mainly causes respiratory diseases, growing data indicate that SARS-CoV-2 can also invade the central nervous system (CNS) and peripheral nervous system ...
Dandan Wan +6 more
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Molecular Therapy: Methods & Clinical Development, 2021 Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) are used for cardiac safety assessment but have limitations for the evaluation of drug-induced contractility.
Kiyoshi Tadano +7 more
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Biodegradable nanoparticles of methoxy poly(ethylene glycol)-b-poly( d, l-lactide)/methoxy poly(ethylene glycol)- b-poly(ϵ-caprolactone) blends for drug delivery [PDF]
, 2012 The effects of blend weight ratio and polyester block length of methoxy poly(ethylene glycol)-b-poly( d, l-lactide) (MPEG- b-PDLL)/methoxy poly(ethylene glycol)- b-poly(ϵ-caprolactone) (MPEG- b-PCL) blends on nanoparticle characteristics and drug release
Yaowalak Srisuwan, Yodthong Baimark
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Functionalized MoS2 nanosheet-capped periodic mesoporous organosilicas as a multifunctional platform for synergistic targeted chemo-photothermal therapy [PDF]
, 2018 The combination of different therapies into a single platform has attracted increasing attention as a potential synergistic tumor treatment. Herein, the fabrication of a novel folate targeted system for chemo-photothermal therapy by using thioether ...
Bremner, David H. +7 more
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Journal of Analytical Methods in Chemistry, 2020 The infusion bag is mainly made up of polyolefin polymer. Antioxidants are usually added to these polymer materials in the production process to prevent the materials from aging and enhance the stability of the materials. Because of the potential harm of
Bo Tao +8 more
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Bio-Inspired Amphiphilic Block-Copolymers Based on Synthetic Glycopolymer and Poly(Amino Acid) as Potential Drug Delivery Systems [PDF]
, 2020 In this work, a method to prepare hybrid amphiphilic block copolymers consisting of biocompatible synthetic glycopolymer with non-degradable backbone and biodegradable poly(amino acid) (PAA) was developed.
Dobrodumov, Anatoliy +10 more
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Drugs, Crime, Space, and Time: A Spatiotemporal Examination of Drug Activity and Crime Rates [PDF]
, 2020 To take stock of the “neighborhood effects” of drug activity, we combined theoretical insights from the drugs and crime and communities and place literatures in examining the longitudinal relationship between drug activity and crime rates at more ...
Contreras, C, Hipp, JR
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