Pillararenes as Promising Carriers for Drug Delivery [PDF]
Since their discovery in 2008 by N. Ogoshi and co-authors, pillararenes (PAs) have become popular hosts for molecular recognition and supramolecular chemistry, as well as other practical applications. The most useful property of these fascinating macrocycles is their ability to accommodate reversibly guest molecules of various kinds, including drugs or
Grigory V. Zyryanov+5 more
openaire +2 more sources
A systematic approach to the formulation of anti-onychomycotic nail patches [PDF]
Nail patches have a potential role as drug carriers for the topical treatment of nail diseases such as onychomycosis, a common condition. O ur aim was therefore to develop a systematic and novel appr oach to the formulat ion of a simple drug -in-adhesive
Charalambides, MN+5 more
core +1 more source
Predicting the vascular adhesion of deformable drug carriers in narrow capillaries traversed by blood cell [PDF]
In vascular targeted therapies, blood-borne carriers should realize sustained drug release from the luminal side towards the diseased tissue. In this context, such carriers are required to firmly adhere to the vessel walls for a sufficient period of time while resisting force perturbations induced by the blood flow and circulating cells. Here, a hybrid
arxiv +1 more source
Multifunctional nanocarriers for lung drug delivery [PDF]
Nanocarriers have been increasingly proposed for lung drug delivery applications. The strategy of combining the intrinsic and more general advantages of the nanostructures with specificities that improve the therapeutic outcomes of particular clinical ...
Grenha, Ana, Pontes, Jorge Filipe
core +2 more sources
Surface Plasmon Resonance as a Characterization Tool for Lipid Nanoparticles Used in Drug Delivery
The development of drug carriers based in lipid nanoparticles (LNPs) aims toward the synthesis of non-toxic multifunctional nanovehicles that can bypass the immune system and allow specific site targeting, controlled release and complete degradation of ...
Cecilia Yamil Chain+4 more
doaj +1 more source
Development and Characterization of Nanoliposomal Hydroxyurea Against BT-474 Breast Cancer Cells [PDF]
Purpose: Hydroxyurea (HU) is a well-known chemotherapy drug with several side effects which limit its clinical application. This study was conducted to improve its therapeutic efficiency against breast cancer using liposomes as FDA-approved drug carriers.
Azam Akbari+5 more
doaj +1 more source
POLYURETHANE COMPOSITES AS DRUG CARRIERS:: RELEASE PATTERNS [PDF]
Biodegradable polyurethanes attract interest of those developing composite materials for biomedical applications. One of their features is their ability to serve as carriers, or matrixes, for medicines and other bioactive compounds to produce a ...
M. V. Grigoreva
doaj +1 more source
A simple molecular modeling method for the characterization of polymeric drug carriers [PDF]
A simple molecular modeling method for the characterization of polymeric drug carriers is presented. Six biodegradable polymers have been investigated as drug carriers using molecular simulations: l-polylactide, d-polylactide, chitosan, polyglycolic acid,
Macháčková, Miroslava+2 more
core +1 more source
Channel Modeling for Drug Carrier Matrices [PDF]
Molecular communications is a promising framework for the design of controlled-release drug delivery systems. In this framework, drug carriers are modeled as transmitters, the diseased cells as absorbing receivers, and the channel between transmitter and receiver as diffusive channel.
arxiv
Probing the luminal microenvironment of reconstituted epithelial microtissues. [PDF]
Polymeric microparticles can serve as carriers or sensors to instruct or characterize tissue biology. However, incorporating microparticles into tissues for in vitro assays remains a challenge.
Cerchiari, Alec E+7 more
core +2 more sources