Results 41 to 50 of about 212,322 (308)

Effect of Cilostazol-Loaded PCL/PEG Nanocapsules on Abdominal Aortic Tunics and Lipid Profile of Wistar Rats [PDF]

open access: yesBrazilian Archives of Biology and Technology, 2020
Cilostazol (CLZ) is a phosphodiesterase III inhibitor with antiplatelet and vasodilator properties. It has been recently verified that CLZ plays a significant role in the arteries by inhibiting the proliferation and growth of muscle cells, increasing the
Luís Daniel Silva Pilatti   +6 more
doaj   +1 more source

Use of artificial cells as drug carriers

open access: yesMaterials Chemistry Frontiers, 2021
Cells are the fundamental functional units of biological systems and mimicking their size, function and complexity is a primary goal in the development of new therapeutic strategies.
Sibel Emir Diltemiz   +7 more
openaire   +5 more sources

Colloidal carriers for ophthalmic drug delivery [PDF]

open access: yes, 2005
To achieve effective drug concentration at the intended site for a sufficient period of time is a requisite desired for many drug formulations. For drugs intended to ocular delivery, its poor bioavailability is due to pre-corneal factors.
Cinto, P. O.   +7 more
core   +1 more source

Recent Advances in Porous Carriers for Drug Delivery: Materials, Loading Strategies, and Applications [PDF]

open access: yesالمجلة العراقية للصيدلة
Background: Poor aqueous solubility and low bioavailability of many drugs remain major challenges in pharmaceutical development and often limit the therapeutic efficacy.
Shahd Hazim   +2 more
doaj   +1 more source

Exosomes: Diagnostic and Therapeutic Implications in Cancer

open access: yesPharmaceutics, 2023
Exosomes are a subset of extracellular vesicles produced by all cells, and they are present in various body fluids. Exosomes play crucial roles in tumor initiation/progression, immune suppression, immune surveillance, metabolic reprogramming ...
Hyein Jo, Kyeonghee Shim, Dooil Jeoung
doaj   +1 more source

Activated carbon as a carrier for amorphous drug delivery: Effect of drug characteristics and carrier wettability [PDF]

open access: yesEuropean Journal of Pharmaceutics and Biopharmaceutics, 2017
Recent research on porous silica materials as drug carriers for amorphous and controlled drug delivery has shown promising results. However, due to contradictory literature reports on toxicity and high costs of production, it is important to explore alternative safe and inexpensive porous carriers.
Miriyala, Nikhila   +4 more
openaire   +5 more sources

Important application value of injectable hydrogels loaded with omeprazole Schiff base complex in the treatment of pancreatitis

open access: yesOpen Chemistry, 2023
In this study, a novel Ho(iii) coordination complex with the chemical composition of [Ho6(acac)4L4(CH3O)6]·xCH3OH (1) has been prepared via using a polydentate Schiff base ligand N′-(2,3-dihydroxybenzylidene) picolinohydrazide (H2L) and a β-diketone ...
Ma Jingrong   +5 more
doaj   +1 more source

Anti-Leishmanial Effects of Chitosan-Polyethylene Oxide Nanofibers Containing Berberine: An Applied Model for Leishmania Wound Dressing [PDF]

open access: yesIranian Journal of Medical Sciences, 2020
Background: Leishmaniasis is the most important parasitic disease in Iran and is the third highest rate of rural cutaneous leishmaniasis in the world. Chitosan-polyethylene oxide nanocomposite fibers can be a suitable replacement for ordinary bandages ...
Mohsen Rahimi   +3 more
doaj   +1 more source

Genomic Diversity and Clinical Variability in Pediatric Primary Cutaneous Anaplastic Large Cell Lymphoma: A Case Series

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Primary cutaneous anaplastic large cell lymphoma (pcALCL) is a rare pediatric CD30‐positive T‐cell lymphoproliferative disorder with an excellent prognosis, but its genomic drivers are poorly defined. We report three children with skin‐limited disease demonstrating striking molecular heterogeneity, including NPM::ALK, NUP214::FRK, and a novel ...
Shoshana Greenberger   +7 more
wiley   +1 more source

Engineering the drug carrier biointerface to overcome biological barriers to drug delivery [PDF]

open access: yes, 2020
Micro and nanoscale drug carriers must navigate through a plethora of dynamic biological systems prior to reaching their tissue or disease targets.
Finbloom, Joel A   +3 more
core   +1 more source

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