Chitosan Contribution to Therapeutic and Vaccinal Approaches for the Control of Leishmaniasis
The control of leishmaniases, a complex parasitic disease caused by the protozoan parasite Leishmania, requires continuous innovation at the therapeutic and vaccination levels.
Philippe M. Loiseau +2 more
doaj +1 more source
Erythrocytes as Carriers: From Drug Delivery to Biosensors
Drug delivery using natural biological carriers, especially erythrocytes, is a rapidly developing field. Such erythrocytes can act as carriers that prolong the drug’s action due to its gradual release from the carrier; as bioreactors with ...
Larisa Koleva +3 more
core +1 more source
Effect of Cilostazol-Loaded PCL/PEG Nanocapsules on Abdominal Aortic Tunics and Lipid Profile of Wistar Rats [PDF]
Cilostazol (CLZ) is a phosphodiesterase III inhibitor with antiplatelet and vasodilator properties. It has been recently verified that CLZ plays a significant role in the arteries by inhibiting the proliferation and growth of muscle cells, increasing the
Luís Daniel Silva Pilatti +6 more
doaj +1 more source
Engineering the drug carrier biointerface to overcome biological barriers to drug delivery [PDF]
Micro and nanoscale drug carriers must navigate through a plethora of dynamic biological systems prior to reaching their tissue or disease targets.
Finbloom, Joel A +3 more
core +1 more source
Exosomes: Diagnostic and Therapeutic Implications in Cancer
Exosomes are a subset of extracellular vesicles produced by all cells, and they are present in various body fluids. Exosomes play crucial roles in tumor initiation/progression, immune suppression, immune surveillance, metabolic reprogramming ...
Hyein Jo, Kyeonghee Shim, Dooil Jeoung
doaj +1 more source
Nano-carriers and their drug release
One of the hottest fields in biomedicine research is to encapsulate drugs and release them in particular organs by using nano-platform.Because nanoparticles can enter most cancer cells easily and accumulate inside the cells,drug-loaded nanoparticles with
Deng Guang +3 more
doaj +1 more source
In this study, a novel Ho(iii) coordination complex with the chemical composition of [Ho6(acac)4L4(CH3O)6]·xCH3OH (1) has been prepared via using a polydentate Schiff base ligand N′-(2,3-dihydroxybenzylidene) picolinohydrazide (H2L) and a β-diketone ...
Ma Jingrong +5 more
doaj +1 more source
Anti-Leishmanial Effects of Chitosan-Polyethylene Oxide Nanofibers Containing Berberine: An Applied Model for Leishmania Wound Dressing [PDF]
Background: Leishmaniasis is the most important parasitic disease in Iran and is the third highest rate of rural cutaneous leishmaniasis in the world. Chitosan-polyethylene oxide nanocomposite fibers can be a suitable replacement for ordinary bandages ...
Mohsen Rahimi +3 more
doaj +1 more source
Polysaccharides in Ocular Drug Delivery [PDF]
Polysaccharides, such as cellulose, hyaluronic acid, alginic acid, and chitosan, as well as polysaccharide derivatives, have been successfully used to augment drug delivery in the treatment of ocular pathologies.
Arto Urtti +9 more
core +1 more source
Recent Advances in Porous Carriers for Drug Delivery: Materials, Loading Strategies, and Applications [PDF]
Background: Poor aqueous solubility and low bioavailability of many drugs remain major challenges in pharmaceutical development and often limit the therapeutic efficacy.
Shahd Hazim +2 more
doaj +1 more source

