Results 21 to 30 of about 2,331,898 (261)

Cells and cell derivatives as drug carriers for targeted delivery

open access: yesMedicine in Drug Discovery, 2019
For over a century, researchers have focused on how to optimize drug delivery. Systemic administration means that the drug becomes dilute and has the potential to diffuse to all tissues, which is only until the immune system steps in and rapidly clears ...
Halle Lutz   +3 more
doaj   +1 more source

Characterization of Colloidal Drug Carriers [PDF]

open access: yes, 1993
Hydrophobic interaction chromatography (HIC) is presented as a suitable method to determine the surface hydrophobicity of colloidal drug carriers. The experimental design is described in great detail.
Müller, R. H., Blunk, Torsten, Mak, E.
core   +1 more source

Hyaluronic Acid-Modified and Doxorubicin-Loaded Gold Nanoparticles and Evaluation of Their Bioactivity

open access: yesPharmaceuticals, 2021
Functionalized gold nanoparticles (AuNPs) have been successfully used in many fields as a result of having low cytotoxicity, good biocompatibility, excellent optical properties, and their ability to target cancer cells. Here, we synthesized AuNP carriers
Lin-Song Li   +5 more
doaj   +1 more source

Hyaluronic Acid-Based Nanomaterials Applied to Cancer: Where Are We Now?

open access: yesPharmaceutics, 2022
Cancer cells normally develop the ability to rewire or reprogram themselves to become resistant to treatments that were previously effective. Despite progress in understanding drug resistance, knowledge gaps remain regarding the underlying biological ...
Vera Machado   +2 more
doaj   +1 more source

Composing On-Program Triggers and On-Demand Stimuli into Biosensor Drug Carriers in Drug Delivery Systems for Programmable Arthritis Therapy

open access: yesPharmaceuticals, 2022
Medication in arthritis therapies is complex because the inflammatory progression of rheumatoid arthritis (RA) and osteoarthritis (OA) is intertwined and influenced by one another. To address this problem, drug delivery systems (DDS) are composed of four
Yan Yik Lim   +2 more
doaj   +1 more source

Star-shaped poly(ε-caprolactones) with well-defined architecture as potential drug carriers [PDF]

open access: yesJournal of the Serbian Chemical Society, 2022
The present study reports the potential application of star-shaped poly(ε-caprolactones) with different number of arms as new drug delivery matrix. Linear and star-shaped PCL ibuprofen loaded microspheres were prepared using oil-in-water (o/w) solvent ...
Ponjavić Marijana   +5 more
doaj   +1 more source

Cyclodextrin-based nanosponges as drug carriers

open access: yesBeilstein Journal of Organic Chemistry, 2012
Cyclodextrin-based nanosponges, which are proposed as a new nanosized delivery system, are innovative cross-linked cyclodextrin polymers nanostructured within a three-dimensional network.
Francesco Trotta   +2 more
doaj   +1 more source

Vesicular Carriers for Follicular Drug Delivery [PDF]

open access: yesPharmaceutical Sciences
The follicular route has been explored for both topical and systemic drug delivery but its application is challenged by different limitations such as sebum flow and size-selectivity.
Mostafa Amirinejad   +3 more
doaj   +1 more source

Why nanodiamond carriers manage to overcome drug resistance in cancer [PDF]

open access: yes, 2020
Nanodiamonds represent an attractive potential carrier for anticancer drugs. The main advantages of nanodiamond particles with respect to medical applications are their high compatibility with non-cancerous cells, feasible surface decoration with ...
Benson, Veronika   +4 more
core   +1 more source

Preparation of amphiphilic magnetic polyvinyl alcohol targeted drug carrier and drug delivery research

open access: yesDesigned Monomers and Polymers, 2020
Currently, magnetic applications have great potential for development in the field of drug carriers. In this paper, Fe3O4-PVA@SH, an amphiphilic magnetically targeting drug carrier, was prepared by using Fe3O4 and PVA with thiohydrazide ...
Yazhen Wang   +6 more
doaj   +1 more source

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