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In recent years, there has been an exponential interest in the development of novel drug delivery systems using drug carriers. Drug carriers offer significant advantages over the conventional drug delivery systems in terms of high stability, high specificity, high drug loading capacity, controlled release of drug and ability to deliver both hydrophilic
CHEKWUBE EZEGBE +2 more
core +5 more sources
Nanoparticulate carriers for drug delivery
Drug delivery with nanoparticulate carriers is a new and upcoming research area that is making major changes within the pharmaceutical industry. Nanoparticulate carriers are discussed, particularly, engineered nanoparticulate carriers used as drug delivery systems for targeted delivery.
Crossen, Samantha Lokelani +1 more
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Self-microemulsifying drug delivery systems (SMEDDS) offer potential for improving the oral bioavailability of poorly water-soluble drugs. However, their susceptibilities during long term storage and in vivo precipitation issues limit their successful ...
Tao Yi, Jifen Zhang
doaj +2 more sources
Because free therapeutic drug molecules often have adverse effects on normal tissues, deliver scanty drug concentrations and exhibit a potentially low efficacy at pathological sites, various drug carriers have been developed for preclinical and clinical ...
Yanqi Huang +3 more
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Microbial Exopolysaccharides as Drug Carriers [PDF]
Microbial exopolysaccharides are peculiar polymers that are produced by living organisms and protect them against environmental factors. These polymers are industrially recovered from the medium culture after performing a fermentative process. These materials are biocompatible and biodegradable, possessing specific and beneficial properties for ...
Tabernero A., Cardea S.
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Drug delivery using a surfactant vehicle has the potential to prevent systemic side effects by delivering therapeutic agents directly to the respiratory system. The inherent chemical properties of surfactant allows it to readily distribute throughout the respiratory system.
Arun, Sett +2 more
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Functionalized Halloysite Nanotubes as Potential Drug Carriers. [PDF]
The aim of the work was to examine the possibility of using modified halloysite nanotubes as a gentamicin carrier and to determine the usefulness of the modification in terms of the effect on the amount of the drug attached, its release time, but also on
Stodolak-Zych E +5 more
europepmc +2 more sources
Microgels as drug carriers for sonopharmacology [PDF]
AbstractThe ultrasound‐induced cleavage of covalent and non‐covalent bonds to activate drugs (sonopharmacology) is a promising concept to gain control over the action of active pharmaceutical ingredients by an external trigger. Previously, linear polymer architectures bearing drug payloads were exploited for drug release by using the principles of ...
Zou, Miancheng +4 more
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Ethosomes: A novel drug carrier
Ethosomal systems are newer lipid vesicular carriers that have been around for 20 years, but over that period they have grown significantly as a means of transdermal drug delivery. They have a sizable amount of ethanol in them. These nanocarriers carry medicinal substances with various physicochemical qualities throughout the skin and deep skin layers.
Chauhan, Neha +6 more
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Aptamers as Both Drugs and Drug-Carriers [PDF]
Aptamers are short nucleic acid oligos. They may serve as both drugs and drug-carriers. Their use as diagnostic tools is also evident. They can be generated using various experimental, theoretical, and computational techniques. The systematic evolution of ligands by exponential enrichment which uses iterative screening of nucleic acid libraries is a ...
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