Results 61 to 70 of about 2,200,984 (302)
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Dendrimers: novel carriers for drug delivery
Journal of Applied Pharmaceutical Research, 2016 Dendrimers are highly branched, organic compounds with well-defined, symmetrical structure. From chemical point of view they are three-dimensional polymers, characterized by a globular shape. At the end of the arms are terminals, functional groups, which
H. S. Chaudhari +3 more
doaj
PharmaceuticsIn the 21st century, thanks to advances in biotechnology and developing pharmaceutical technology, significant progress is being made in effective drug design.
Fatih Ciftci +5 more
doaj +1 more source
Cyclodextrin-based biological stimuli-responsive carriers for smart and precision medicine [PDF]
, 2017 Spurred on by recent progress in nanotechnology and precision medicine, smart drug carriers are entering an entirely new era. Smart drug carriers have been widely studied in recent years as a result of their ability to control drug release under ...
Liao, Rongqiang +11 more
core +2 more sources
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Frontiers in Molecular BiosciencesExtracellular vesicles derived from mesenchymal stem cells (MSC-EVs) have biocompatibility and low immunogenicity. They can effectively mediate intercellular communication by transmitting various information molecules, including polypeptides, lipids, and
Na Liu +7 more
doaj +1 more source
The glyconanoparticle as carrier for drug delivery [PDF]
Drug Delivery, 2018 The glyconanoparticle (GlycoNP) has multiple effects and has important applications in drug delivery and bioimaging. It not only has the advantages of nano drug delivery system but also utilizes the characteristics of multivalent interaction of sugar, which greatly improves the targeting of drug delivery.
Xueqin Zhang +2 more
openaire +3 more sources
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Liposomes in dermatological diseases
Journal of Applied Pharmaceutical Research, 2017 Liposomes are vesicles comprising of spherical phospholipids making them useful for topical applications of drugs. Liposome research has been expanded considerably and nowadays, it is possible to construct a wide range of liposomes varying in size ...
M. Kamra, A Diwan
doaj
Colloidal carriers for ophthalmic drug delivery
, 2005 To achieve effective drug concentration at the intended site for a sufficient period of time is a requisite desired for many drug formulations. For drugs intended to ocular delivery, its poor bioavailability is due to pre-corneal factors.
Cinto, P. O. +7 more
core +1 more source