Results 61 to 70 of about 212,322 (308)
FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Combination of drugs and carriers in drug delivery technology and its development [PDF]
, 2019 Ying Du, Baoan ChenDepartment of Hematology and Oncology, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, People’s Republic of ChinaAbstract: The development of drug-loading technology will bring new and rapid development to ...
Du Y, Chen B
core
An Atypical Mitochondrial Carrier That Mediates Drug Action in Trypanosoma brucei [PDF]
, 2015 Elucidating the mechanism of action of trypanocidal compounds is an important step in the development of more efficient drugs against Trypanosoma brucei. In a screening approach using an RNAi library in T. brucei bloodstream forms, we identified a member
Vial, Henri +28 more
core +1 more source
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Chiral of D-type mesoporous silica deliver anti-inflammatory drug with double synergism
Materials Today AdvancesChiral drug delivery systems have gained great attention in novel drug delivery applications. To explore their exceptional functions, a series of chiral mesoporous silica xerogel (L-SX, D-SX) was constructed using biomimetic method and another series of ...
Xue Yan +4 more
doaj +1 more source
Polymers and Polymer Nanocomposites for Cancer Therapy
Applied Sciences, 2019 Synthetic polymers, biopolymers, and their nanocomposites are being studied, and some of them are already used in different medical areas. Among the synthetic ones that can be mentioned are polyolefins, fluorinated polymers, polyesters, silicones, and ...
Dorel Feldman
doaj +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Drug targeting to tumors using HPMA copolymers [PDF]
, 2009 Copolymers based on N-(2-hydroxypropyl)methacrylamide (HPMA) are prototypic and well-characterized polymeric drug carriers that have been broadly implemented in the delivery of anticancer agents.
Dep Farmaceutische wetenschappen +2 more
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Cyclodextrin-based biological stimuli-responsive carriers for smart and precision medicine [PDF]
, 2017 Spurred on by recent progress in nanotechnology and precision medicine, smart drug carriers are entering an entirely new era. Smart drug carriers have been widely studied in recent years as a result of their ability to control drug release under ...
Liao, Rongqiang +11 more
core +1 more source
Exosomes as Drug Carriers in Anti-Cancer Therapy
Frontiers in Cell and Developmental Biology, 2022 Over the years, there has been a high demand for developing new safe and effective drug carriers for cancer therapy. Emerging studies have indicated that exosomes can serve as potent therapeutic carriers since they offer low immunogenicity, high ...
Lan Chen +7 more
doaj +1 more source