Results 81 to 90 of about 212,322 (308)

NIOSOMES:THE UNIQUE VESICULAR DRUG CARRIERS [PDF]

open access: yes, 2012
Drug targeting is the ability to direct a therapeutic agent specifically to desired site of action with little or no interaction with nontarget tissue. Niosomes are one of the best carriers for drug targeting.
Arora, Sonia   +4 more
core   +2 more sources

Liposomes in dermatological diseases

open access: yesJournal of Applied Pharmaceutical Research, 2017
Liposomes are vesicles comprising of spherical phospholipids making them useful for topical applications of drugs. Liposome research has been expanded considerably and nowadays, it is possible to construct a wide range of liposomes varying in size ...
M. Kamra, A Diwan
doaj  

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Computer simulation of a pH-responsive drug delivery system formed by μ-ABC miktoarm star polymers in aqueous solution

open access: yesInternational Journal of Smart and Nano Materials
The development of pH-responsive drug delivery systems is a critical frontier in the field of targeted cancer therapy. This study presents a comprehensive investigation into the self-assembly and drug release behavior of a pH-responsive anticancer drug ...
Zengwei Ma   +4 more
doaj   +1 more source

Design of Chitosan and Its Water Soluble Derivatives-Based Drug Carriers with Polyelectrolyte Complexes

open access: yesMarine Drugs, 2014
Chitosan, the cationic polysaccharide derived from the natural polysaccharide chitin, has been studied as a biomaterial for more than two decades. As a polycationic polymer with favorable properties, it has been widely used to form polyelectrolyte ...
Qing-Xi Wu   +2 more
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Advancements in Cell Membrane–Based Biomimetic Carriers for Antitumor Therapy

open access: yesZhongliu Fangzhi Yanjiu
Drug delivery technologies are crucial components in drug development, greatly enhancing drug bioavailability and therapeutic efficacy and reducing toxic side effects.
Jiahe WU   +3 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Engineering antiphagocytic biomimetic drug carriers [PDF]

open access: yes, 2013
Drug-delivery carriers have the potential to not only treat but also diagnose many diseases; however, they still lack the complexity of natural-particulate systems.
Sawdon, Alicia J., Peng, Ching An
core   +1 more source

Home - About - Disclaimer - Privacy