Results 51 to 60 of about 322,888 (285)
Drug checking: a potential solution to the opioid overdose epidemic?
Substance Abuse Treatment, Prevention, and Policy, 2018 Background North America is experiencing an overdose epidemic driven in part by the proliferation of illicitly-manufactured fentanyl and related analogues. In response, communities are scaling up novel overdose prevention interventions. Included are drug
Geoff Bardwell, Thomas Kerr
doaj +1 more source
Design of a wireless patient diagnosis system [PDF]
, 2012 Medical administrative and diagnosis procedures require the retrieval of patient diagnosis history before treatments and drug administration. This involves careful checking of the patient past record which might be stored electronically or in paper ...
Holmes, Violeta, Jimoh, F.
core
, 2010 High-throughput biological assays such as microarrays let us ask very detailed questions about how diseases operate, and promise to let us personalize therapy.
Baggerly, Keith A., Coombes, Kevin R.
core +1 more source
Ageing makes us dyslexic [PDF]
, 2013 Background: The effects of typical ageing on spoken language are well known: word production is disproportionately affected while syntactic processing is relatively well preserved.
Harley, Trevor A. +3 more
core +3 more sources
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Patient Risk and Data Standards in Healthcare Supply Chain [PDF]
, 2013 Patient safety is one of the most important health care challenges. It is a big concern since 1 in every 10 patients around the world is affected by healthcare errors.
Farrokhvar, Paiman
core +2 more sources
Towards Cancer Hybrid Automata
, 2012 This paper introduces Cancer Hybrid Automata (CHAs), a formalism to model the progression of cancers through discrete phenotypes. The classification of cancer progression using discrete states like stages and hallmarks has become common in the biology ...
Andreas Witzel +4 more
core +2 more sources
QSAR study for carcinogenicity in a large set of organic compounds [PDF]
, 2012 In our continuing efforts to find out acceptable Absorption, Distribution, Metabolization, Elimination and Toxicity (ADMET) properties of organic compounds, we establish linear QSAR models for the carcinogenic potential prediction of 1464 compounds taken
Castro, Eduardo Alberto +3 more
core +2 more sources
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Harm Reduction Journal, 2021 Background The North American opioid overdose crisis is driven in large part by the presence of unknown psychoactive adulterants in the dynamic, unregulated drug supply.
Jeanette M. Bowles +8 more
doaj +1 more source