Results 71 to 80 of about 322,888 (285)
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
Audit-based Compliance Control (AC2) for EHR Systems [PDF]
, 2007 Traditionally, medical data is stored and processed using paper-based files. Recently, medical facilities have started to store, access and exchange medical data in digital form.
Dekker, M.A.C. +2 more
core +1 more source
FEBS Open Bio, EarlyView.KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani +6 more
wiley +1 more source
Harm Reduction Journal, 2023 Background The opioid epidemic continues to be associated with high numbers of fatalities in the USA and other countries, driven mainly by the inclusion of potent synthetic opioids in street drugs.
James A. Swartz +7 more
doaj +1 more source
Drugs arriving in Kosovo need checking
BMJ, 1999 EDITOR—3As deputy head and consultants of the health department of EUAM (European Union Administration of Mostar) in 1995-6 we were impressed by Saunders's article concerning drug donations.1 In Bosnia these problems appeared for a variety of complex reasons that have been widely recognised.2–4 The problem of private donations in former Yugoslavia was ...
G. L. Quaglio, P. Mezzelani, C. Cuchillo
openaire +2 more sources
FEBS Open Bio, EarlyView.dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon +6 more
wiley +1 more source
Harm Reduction Journal, 2021 Background Drug checking is a harm reduction intervention aiming to reduce substance use-related risks by improving drug user knowledge of the composition of unregulated drugs.
Tara Beaulieu +6 more
doaj +1 more source
Antecedent selection techniques for high-recall roreference resolution [PDF]
, 2007 We investigate methods to improve the recall in coreference resolution by also trying to resolve those definite descriptions where no earlier mention of the referent shares the same lexical head (coreferent bridging). The problem, which is notably harder
Versley, Yannick
core
FEBS Open Bio, EarlyView.A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti +3 more
wiley +1 more source
Anchorage‐independent and faster growth in clonal population from UV‐irradiated NER‐deficient cells
FEBS Open Bio, EarlyView.UV‐irradiated cells expressing a DDB2 mutant protein unable to interact with PCNA (DDB2PCNA‐) form clones able to grow without anchorage. Different experimental approaches reveal heterogeneity in cell cycle regulation and drug response within these clones, emphasizing the crucial role of the DDB2‐PCNA interaction in preventing cellular transformation ...
Paola Perucca +6 more
wiley +1 more source