Results 231 to 240 of about 2,583,563 (290)

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

FEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu, Lanlan Li, Wenjuan Jia, Hanzhong Feng, Xiaoquan Yu, Youli Zhao, Fengzhi Yuan, Hui Ding, Junqiang Tian, Yong‐Xing He, Zhiping Wang   +10 more
wiley   +1 more source

Novel immune drug combination induces tumour microenvironment remodelling and reduces the dosage of anti-PD-1 antibody. [PDF]

Sci Rep
Ozasa T, Nakajima M, Tsunedomi R, Goto S, Adachi K, Takahashi H, Tamada K, Nagano H.   +7 more
europepmc   +1 more source

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

FEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao, Daiki Kobayashi, Shogo Hori, Osamu Saitoh   +3 more
wiley   +1 more source

Targeting the core program of metastasis with a novel drug combination. [PDF]

Cancer Med
Fnu G, Weber GF.
europepmc   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Correction to "A Senomorphlytic Three-Drug Combination Discovered in Salsola collina for Delaying Aging Phenotypes and Extending Healthspan". [PDF]

Adv Sci (Weinh)
europepmc   +1 more source

A weighted Bayesian integration method for predicting drug combination using heterogeneous data. [PDF]

J Transl Med
Li T, Xiao L, Geng H, Chen A, Hu YQ.
europepmc   +1 more source

Two-Drug Combination Antiretroviral Therapy for HIV-1: Case Series and Literature Review. [PDF]

Hosp Pharm
Martley TJ, Fanizza F, Penn C, Burling M.   +3 more
europepmc   +1 more source

Multicentre controlled open randomised clinical trial to assess efficacy and safety of an anti-tuberculosis drug combination based on optimised-dose rifampicin, optimised-dose moxifloxacin and optimised-dose linezolid for TB: the RML-TB trial protocol. [PDF]

BMJ Open Respir Res
Diab Casares L, Espinosa Pereiro J, Tórtola Fernández MT, Casas García X, Millet JP, Pomar Solchaga V, Navas Elorza E, Troya García J, Díaz de Santiago A, Luque Márquez R, Medina Gallardo JF, González Galán V, Montero Alonso M, Gil Brusola A, Rabuñal Rey R, Anibarro García L, Sanz Herrero F, Guna Serrano R, Garrigó Fullola M, Tato Díez M, Talavan Zanón T, Portero MF, Alonso García P, Saez López AM, Aznar ML, Martínez Campreciós J, Saborit N, Sánchez Montalvá A.   +27 more
europepmc   +1 more source

Ultrasmall solid lipid nanoparticles as a potential innovative delivery system for a drug combination against glioma. [PDF]

Nanomedicine (Lond)
Battaglia L, Dianzani C, Muntoni E, Marini E, Bozza A, Bordano V, Ferraris C, Garelli S, Valsania MC, Terreno E, Capozza M, Costanzo D, Capucchio MT, Hassan T, Pizzimenti S, Pettineo E, Di Muro M, Scorziello F.   +17 more
europepmc   +1 more source