Results 241 to 250 of about 80,065 (281)
Some of the next articles are maybe not open access.
Compound Data Mining for Drug Discovery
2016In recent years, there has been unprecedented growth in compound activity data in the public domain. These compound data provide an indispensable resource for drug discovery in academic environments as well as in the pharmaceutical industry. To handle large volumes of heterogeneous and complex compound data and extract discovery-relevant knowledge from
openaire +2 more sources
TRPs: Modulation by Drug-Like Compounds
2014Drug-like compounds that exert biological activity towards TRP channels are either being used as cell biological tools or further developed into pharmacological lead structures aiming at therapeutic use in diseased states. Although drug-likeliness is not easy to predict, common rules include a relatively low molecular weight, physicochemical ...
openaire +2 more sources
Prediction of Transporter-Mediated Drug–Drug Interactions Using Endogenous Compounds
Clinical Pharmacology & Therapeutics, 2012Therapy with two or more drugs is more the rule than the exception, particularly in aging societies. Drug-drug interactions are frequently undesirable and may lead to increased toxicity and mortality. Inhibition of transporters is one major mechanism underlying drug-drug interactions.
openaire +2 more sources
Antibody–drug conjugates: Smart chemotherapy delivery across tumor histologies
Ca-A Cancer Journal for Clinicians, 2022Paolo Tarantino +2 more
exaly
Targeted drug delivery strategies for precision medicines
Nature Reviews Materials, 2021Mandana T Manzari +2 more
exaly
Anti-tuberculosis treatment strategies and drug development: challenges and priorities
Nature Reviews Microbiology, 2022Véronique A Dartois, Eric J Rubin
exaly
Allergic drug eruption from pyrazolone compounds
Contact Dermatitis, 1977R C, Vooys, W G, van Ketel
openaire +2 more sources