The occurrence of drug-drug-interactions (DDI) from multiple drug dispensations is a serious problem, both for individuals and health-care systems, since patients with complications due to DDI are likely to reenter the system at a costlier level.
Correia, Rion Brattig+3 more
core +1 more source
Effect of the Uniform Accident and Sickness Policy Provision Law on Alcohol Screening and Intervention in Trauma Centers [PDF]
Outlines how a law allowing insurers to deny payment for injury claims if alcohol or drug use was involved prevents alcohol screening and interventions to reduce alcohol use, repeat injuries, and healthcare costs.
Deanna Lewis
core +1 more source
Diffusive Mobile MC for Controlled-Release Drug Delivery with Absorbing Receiver [PDF]
Nanoparticle drug carriers play an important role in facilitating efficient targeted drug delivery, i.e., improving treatment success and reducing drug costs and side effects. However, the mobility of nanoparticle drug carriers poses a challenge in designing drug delivery systems.
arxiv
The Cost of Influence: How Gifts to Physicians Shape Prescriptions and Drug Costs [PDF]
This paper studies how gifts - monetary or in-kind payments - from drug firms to physicians in the US affect prescriptions and drug costs. We estimate heterogeneous treatment effects by combining physician-level data on antidiabetic prescriptions and payments with causal inference and machine learning methods.
arxiv
Frequency, factors and costs associated with injection site infections: findings from a national multi-site survey of injecting drug users in England. [PDF]
BACKGROUND: Injection site infections among injecting drug users (IDUs) have been associated with serious morbidity and health service costs in North America.
Hickman, Matthew+4 more
core +3 more sources
National mass drug administration costs for lymphatic filariasis elimination. [PDF]
BACKGROUND: Because lymphatic filariasis (LF) elimination efforts are hampered by a dearth of economic information about the cost of mass drug administration (MDA) programs (using either albendazole with diethylcarbamazine [DEC] or albendazole with ...
Ann S Goldman+21 more
doaj +1 more source
The Harmful Side Effects of Drug Prohibition [PDF]
Some drugs make people feel good. That is why some people use them. Some of these drugs are alleged to have side effects so destructive that many advise against their use. The same may be said about statutes that attempt to prohibit the manufacture, sale,
Barnett, Randy E
core +1 more source
Implementation of functions in R tool in parallel environment [PDF]
Drug promiscuity and polypharmacology are much discussed topics in pharmaceutical research. Drug repositioning applies established drugs to new disease indications with increasing success. As polypharmacology, defined a drug's ability to bind to several targets but due to possible side effects, this feature is not taken into consideration.
arxiv
Estimating the clinical cost of drug development for orphan versus non-orphan drugs
Background High orphan drug prices have gained the attention of payers and policy makers. These prices may reflect the need to recoup the cost of drug development from a small patient pool.
Kavisha Jayasundara+5 more
doaj +1 more source
Network-based Biased Tree Ensembles (NetBiTE) for Drug Sensitivity Prediction and Drug Sensitivity Biomarker Identification in Cancer [PDF]
We present the Network-based Biased Tree Ensembles (NetBiTE) method for drug sensitivity prediction and drug sensitivity biomarker identification in cancer using a combination of prior knowledge and gene expression data. Our devised method consists of a biased tree ensemble that is built according to a probabilistic bias weight distribution.
arxiv