Results 231 to 240 of about 754,926 (313)

Endocytic Programming via Porous Silicon Nanoparticles Enhances TLR4 Nanoagonist Potency for Macrophage‐Mediated Immunotherapy

Advanced Functional Materials, EarlyView.
Porous silicon nanoparticles (PSiNPs) reprogram macrophage endocytosis of manganese@albumin‐based TLR4 nanoagonists, driving TRIF‐biased TLR4 signaling, eliciting robust proinflammatory responses, and potentiating macrophage‐mediated immunotherapeutic effects against NSCLC.
Xiaomei Zhang, Huiying Li, Shuodan Huang, Linxuan Zhang, Yan Gao, Ruoran Wang, Xiaoyu Wang, Hélder A. Santos, Zhenyu Yin, Bing Xia   +9 more
wiley   +1 more source

Advances in Hydrophilic Drug Delivery: Encapsulation of Biotin in Alginate Microparticles. [PDF]

Pharmaceutics
Naveira-Souto I, Rosell-Vives E, Pena-Rodríguez E, Fernandez-Campos F, Lajarin-Reinares M.   +4 more
europepmc   +1 more source

Cholesterol in mRNA‐Lipid Nanoparticles can be Replaced with the Synthetic Mycobacterial Monomycoloyl Glycerol Analogue MMG‐1

Advanced Functional Materials, EarlyView.
This study demonstrates that cholesterol in messenger RNA‐lipid nanoparticles (mRNA‐LNPs) can be completely replaced with an immunopotentiating lipid, i.e., a synthetic analogue of the C‐type lectin receptor agonist monomycoloyl glycerol (MMG‐1), without compromising physicochemical properties, in vivo transfection efficiency, and immunogenicity of the
Abhijeet G. Lokras, Saahil S. Baghel, Rune F. Jensen, Aneesh Thakur, Henrik Franzyk, Oskar Thofte, Marco Herrera‐Barrera, Madeleine Landry, Melike Ongun, Ahmad Tami, Marlene P. Thanthrige, Eva Callens, Corinne Beinat, Thomas Rades, Søren R. Paludan, Kristian Riesbeck, Ida Rosenkrands, Dennis Christensen, Gabriel K. Pedersen, Camilla Foged   +19 more
wiley   +1 more source

Nanoparticle tools for maximizing oral drug delivery. [PDF]

Braz J Med Biol Res
Cahyani DM, Mubarok AS, Hariawan BS, Amalina I, Drake P, Parumasivam T, Sahu RK, Rijal MAS, Sari R, Miatmoko A.   +9 more
europepmc   +1 more source

Transducer Materials Mediated Deep Brain Stimulation in Neurological Disorders

Advanced Functional Materials, EarlyView.
This review discusses advanced transducer materials for improving deep brain stimulation (DBS) in neurological disorders. These materials respond to light, ultrasound, or magnetic fields, enabling precise, less invasive neuromodulation. Their stimulus‐responsive properties enhance neural control and adaptive therapy, paving the way for next‐generation ...
Di Zhao, Zhengyang Cao, Guangjun Zhong, Limin Shi, Junxia Xie, Jianhua Hao   +5 more
wiley   +1 more source

Zein-Based Nanocarriers: Advances in Oral Drug Delivery. [PDF]

Pharmaceutics
Liu Y, An D, Meng X, Deng S, Liu G.
europepmc   +1 more source

Anionic Citrate‐Based 3D‐Printed Scaffolds for Tunable and Sustained Orthobiologic Delivery to Enhance Tissue Regeneration

Advanced Functional Materials, EarlyView.
A potent anionic citric acid‐based 3D‐printed scaffold is developed for the sustained and controlled release of orthobiologics to enhance orthopedic therapeutic efficacy. Comprehensive in vivo studies demonstrated effective bone fusion and high safety at a low dose of BMP‐2 delivered by the system, establishing it as a promising platform for safe ...
Se‐Hwan Lee, Ruqiang Lu, Andrew House, Zizhao Li, Lindsey Hammond Burton, Katie Josephine Sikes, Lynn Marie Pezzanite, Drew William Koch, Kevin Michael Labus, Ben Gadomski, Jeremiah Easley, Richard Tuan Tran, Su Chin Heo   +12 more
wiley   +1 more source

Flux‐Regulated Crystallization of Perovskites Using Machine Learning‐Predicted Solvent Evaporation Rates for X‐Ray Detectors

Advanced Functional Materials, EarlyView.
By integrating machine learning into flux‐regulated crystallization (FRC), accurate prediction of solvent evaporation rates in real time, improving crystallization control and reducing crystal growth variability by over threefold, is achieved. This enhances the reproducibility and quality of perovskite single crystals, leading to reproducible ...
Tatiane Pretto, Sergey Dayneko, Antoine Pavesic Junior, Nicholas Sandor, Alexander Hart, Yuki Haruta, Magdalena Bazalova‐Carter, Marcos J. L. Santos, Makhsud I. Saidaminov   +8 more
wiley   +1 more source