Results 21 to 30 of about 6,817,458 (407)

Controlled Drug Delivery Systems: Current Status and Future Directions

open access: yesMolecules, 2021
The drug delivery system enables the release of the active pharmaceutical ingredient to achieve a desired therapeutic response. Conventional drug delivery systems (tablets, capsules, syrups, ointments, etc.) suffer from poor bioavailability and ...
Shivakalyani Adepu, S. Ramakrishna
semanticscholar   +1 more source

Engineering exosomes for targeted drug delivery

open access: yesTheranostics, 2021
Exosomes are cell-derived nanovesicles that are involved in the intercellular transportation of materials. Therapeutics, such as small molecules or nucleic acid drugs, can be incorporated into exosomes and then delivered to specific types of cells or ...
Yujie Liang   +3 more
semanticscholar   +1 more source

Efficacy of Intra-Articular Injection of Botulinum Toxin Type A (IncobotulinumtoxinA) in Temporomandibular Joint Osteoarthritis: A Three-Arm Controlled Trial in Rats

open access: yesToxins, 2023
Temporomandibular disorders (TMD) are complex pathologies responsible for chronic orofacial pain. Intramuscular injection of botulinum toxin A (BoNT/A) has shown effectiveness in knee and shoulder osteoarthritis, as well as in some TMDs such as ...
Marie Béret   +6 more
doaj   +1 more source

Review on metal nanoparticles as nanocarriers: current challenges and perspectives in drug delivery systems

open access: yesEmergent Materials, 2022
Over the past few years, nanotechnology has been attracting considerable research attention because of their outstanding mechanical, electromagnetic and optical properties.
V. Chandrakala   +2 more
semanticscholar   +1 more source

Solid Lipid Nanoparticles: A Potential Approach for Dermal Drug Delivery [PDF]

open access: yes, 2014
Solid lipid nanoparticles (SLNs) have attracted increasing attention during recent years. Due to their unique size dependent properties, lipid nanoparticles offer possibilities to develop new therapeutics.
Conway, Barbara R, Kakadia, Pratibha G.
core   +1 more source

Nano based drug delivery systems: recent developments and future prospects

open access: yesJournal of Nanobiotechnology, 2018
Nanomedicine and nano delivery systems are a relatively new but rapidly developing science where materials in the nanoscale range are employed to serve as means of diagnostic tools or to deliver therapeutic agents to specific targeted sites in a ...
J. Patra   +11 more
semanticscholar   +1 more source

Nasal drug delivery [PDF]

open access: yesDrug Delivery and Translational Research, 2012
The nasal cavity has for more than three decades been widely explored as a potential alternative route to oral or parenteral administration for systemically active drugs. The nasal route has shown remarkable advantages that include a rapid and high systemic availability, avoidance of first pass metabolism by the liver, and the possibility of targeting ...
Elka, Touitou, Lisbeth, Illum
openaire   +2 more sources

Validation of smart nanoparticles as controlled drug delivery systems: loading and pH-dependent release of pilocarpine [PDF]

open access: yes, 2017
Micelles are good devices for use as controlled drug delivery systems because they exhibit the ability to protect the encapsulated substance from the routes of degradation until they reach the site of action. The present work assesses loading kinetics of
Galbis Fuster, Elsa   +4 more
core   +6 more sources

Evaluation of Drug Delivery and Efficacy of Ciprofloxacin-Loaded Povidone Foils and Nanofiber Mats in a Wound-Infection Model Based on Ex Vivo Human Skin [PDF]

open access: yes, 2019
Topical treatment of wound infections is often a challenge due to limited drug availability at the site of infection. Topical drug delivery is an attractive option for reducing systemic side effects, provided that a more selective and sustained local ...
Bayer, Ilker S.   +6 more
core   +2 more sources

Application of chitosan/alginate nanoparticle in oral drug delivery systems: prospects and challenges

open access: yesDrug Delivery, 2022
Oral drug delivery systems (ODDSs) have various advantages of simple operation and few side effects. ODDSs are highly desirable for colon-targeted therapy (e.g.
Shangyong Li   +8 more
semanticscholar   +1 more source

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