Results 21 to 30 of about 754,926 (313)
Nanoencapsulation for drug delivery [PDF]
EXCLI journal, 2014 Nanoencapsulation of drug/small molecules in nanocarriers (NCs) is a very promising approach for development of nanomedicine. Modern drug encapsulation methods allow efficient loading of drug molecules inside the NCs thereby reducing systemic toxicity associated with drugs.
Kumari, Avnesh +3 more
openaire +3 more sources
A Promising Drug Delivery: Intranasal Drug Delivery System
International Journal of Pharmaceutical Sciences Review and Research, 2021 Pneumonic medication conveyance has acquired gigantic logical interest as of late and has advanced inside the setting of treatment for lung infections. Lung is an appealing climate for bio particles, which are exceptionally presented to enzymatic debasement in the gastrointestinal parcel just as hepatic corruption.
M. Srinivas, Y. Kalyani, J. V. C. Sharma
openaire +2 more sources
Bioengineering & Translational Medicine, 2023 Ionic liquids (ILs) attract more and more interests in improving drug transport across membrane, including transdermal, nasal, and oral delivery. However, some drawbacks of ILs impede the application in oral drug delivery, such as rapid precipitation of ...
Kaiheng Liu +9 more
doaj +1 more source
Sensors, 2017 Photoacoustic (PA) technology holds great potential in clinical translation as a new non-invasive bioimaging modality. In contrast to conventional optical imaging, PA imaging (PAI) enables higher resolution imaging with deeper imaging depth. Besides applications for diagnosis, PA has also been extended to theranostic applications.
Zhen Gu +3 more
openaire +3 more sources
An in situ dual-anchoring strategy for enhanced immobilization of PD-L1 to treat autoimmune diseases
Nature Communications, 2023 Immune checkpoints play key roles in maintaining self-tolerance. Targeted potentiation of the checkpoint molecule PD-L1 through in situ manipulation offers clinical promise for patients with autoimmune diseases.
Shenqiang Wang +9 more
doaj +1 more source
Cancer DNA vaccines: current preclinical and clinical developments and future perspectives
Journal of Experimental & Clinical Cancer Research, 2019 The recent developments in immuno-oncology have opened an unprecedented avenue for the emergence of vaccine strategies. Therapeutic DNA cancer vaccines are now considered a very promising strategy to activate the immune system against cancer. In the past,
Alessandra Lopes +2 more
doaj +1 more source
Efficient Peroral Delivery of Insulin via Vitamin B12 Modified Trimethyl Chitosan Nanoparticles
Journal of Pharmacy & Pharmaceutical Sciences, 2015 PURPOSE: We investigated the effect of vitamin B12 (VB12) modification on the insulin absorption from trimethyl chitosan(TMC) nanoparticles (NPs) under the influence of mucus.
Zhiyang Ke +4 more
doaj +1 more source
Acta Pharmaceutica Sinica B, 2019 Immunotherapy has become a highly promising paradigm for cancer treatment. Herein, a chemo-immunotherapy was developed by encapsulating chemotherapeutic drug doxorubicin (DOX) and Toll-like receptor 7 agonist imiquimod (IMQ) in low molecular weight ...
Jiaojie Wei +9 more
doaj +1 more source
International Journal of Pharmaceutics: X, 2023 We hypothesized that tocopherol succinate (TOS) and D-α-tocopherol polyethylene2000 succinate (TPGS2000) micelles could work as a drug delivery system while enhancing the anti-cancer efficacy of doxorubicin lauryl hydrazone derivative (DOXC12) for the ...
Mingchao Wang +3 more
doaj +1 more source
FEBS Letters, EarlyView.Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu +17 more
wiley +1 more source