Results 21 to 30 of about 6,495,283 (386)
Drug delivery systems for RNA therapeutics
Nature reviews genetics, 2022 RNA-based gene therapy requires therapeutic RNA to function inside target cells without eliciting unwanted immune responses. RNA can be ferried into cells using non-viral drug delivery systems, which circumvent the limitations of viral delivery vectors ...
Kalina Paunovska +2 more
semanticscholar +1 more source
Emergent Materials, 2022 Over the past few years, nanotechnology has been attracting considerable research attention because of their outstanding mechanical, electromagnetic and optical properties.
V. Chandrakala +2 more
semanticscholar +1 more source
Engineering exosomes for targeted drug delivery
Theranostics, 2021 Exosomes are cell-derived nanovesicles that are involved in the intercellular transportation of materials. Therapeutics, such as small molecules or nucleic acid drugs, can be incorporated into exosomes and then delivered to specific types of cells or ...
Yujie Liang +3 more
semanticscholar +1 more source
PLGA-based biodegradable microspheres in drug delivery: recent advances in research and application
Drug Delivery, 2021 Biodegradable microspheres have been widely used in the field of medicine due to their ability to deliver drug molecules of various properties through multiple pathways and their advantages of low dose and low side effects. Poly (lactic-co-glycolic acid)
Yue Su +7 more
semanticscholar +1 more source
Toxins, 2023 Temporomandibular disorders (TMD) are complex pathologies responsible for chronic orofacial pain. Intramuscular injection of botulinum toxin A (BoNT/A) has shown effectiveness in knee and shoulder osteoarthritis, as well as in some TMDs such as ...
Marie Béret +6 more
doaj +1 more source
Controlled Drug Delivery Systems: Current Status and Future Directions
Molecules, 2021 The drug delivery system enables the release of the active pharmaceutical ingredient to achieve a desired therapeutic response. Conventional drug delivery systems (tablets, capsules, syrups, ointments, etc.) suffer from poor bioavailability and ...
Shivakalyani Adepu, S. Ramakrishna
semanticscholar +1 more source
Advances in Oral Drug Delivery
Frontiers in Pharmacology, 2021 The oral route is the most common route for drug administration. It is the most preferred route, due to its advantages, such as non-invasiveness, patient compliance and convenience of drug administration.
Mohammed S. Alqahtani +3 more
semanticscholar +1 more source
Advances in oligonucleotide drug delivery
Nature reviews. Drug discovery, 2020 Oligonucleotides can be used to modulate gene expression via a range of processes including RNAi, target degradation by RNase H-mediated cleavage, splicing modulation, non-coding RNA inhibition, gene activation and programmed gene editing. As such, these
T. Roberts, R. Langer, M. Wood
semanticscholar +1 more source
Enhancement strategies for transdermal drug delivery systems: current trends and applications
Drug Delivery and Translational Research, 2021 Transdermal drug delivery systems have become an intriguing research topic in pharmaceutical technology area and one of the most frequently developed pharmaceutical products in global market.
Delly Ramadon +3 more
semanticscholar +1 more source
Development of α-Tocopherol Succinate-Based Nanostructured Lipid Carriers for Delivery of Paclitaxel
Pharmaceutics, 2022 The management of retinoblastoma (RB) involves the use of invasive treatment regimens. Paclitaxel (PTX), an effective antineoplastic compound used in the treatment of a wide range of malignant tumors, poses treatment challenges due to systemic toxicity ...
Sushrut Marathe +5 more
doaj +1 more source