Results 21 to 30 of about 903,949 (317)
Journal for ImmunoTherapy of Cancer, 2021 Background Strategies to increase nucleic acid vaccine immunogenicity are needed to move towards clinical applications in oncology. In this study, we designed a new generation of DNA vaccines, encoding an engineered vesicular stomatitis virus ...
Alessandra Lopes +8 more
doaj +1 more source
Silica nanoparticles in transmucosal drug delivery [PDF]
, 2020 Transmucosal drug delivery includes the administration of drugs via various mucous membranes, such as gastrointestinal, nasal, ocular, and vaginal mucosa.
Ng, Keng Wooi +7 more
core +1 more source
Drug Delivery and Translational Research, 2012 The nasal cavity has for more than three decades been widely explored as a potential alternative route to oral or parenteral administration for systemically active drugs. The nasal route has shown remarkable advantages that include a rapid and high systemic availability, avoidance of first pass metabolism by the liver, and the possibility of targeting ...
Elka, Touitou, Lisbeth, Illum
openaire +2 more sources
Bioengineering & Translational Medicine, 2023 Ionic liquids (ILs) attract more and more interests in improving drug transport across membrane, including transdermal, nasal, and oral delivery. However, some drawbacks of ILs impede the application in oral drug delivery, such as rapid precipitation of ...
Kaiheng Liu +9 more
doaj +1 more source
Cancer DNA vaccines: current preclinical and clinical developments and future perspectives
Journal of Experimental & Clinical Cancer Research, 2019 The recent developments in immuno-oncology have opened an unprecedented avenue for the emergence of vaccine strategies. Therapeutic DNA cancer vaccines are now considered a very promising strategy to activate the immune system against cancer. In the past,
Alessandra Lopes +2 more
doaj +1 more source
, 2011 The study was aimed at the evaluation of N-vinyl pyrrolidone (NVP) incorporated polymethacrylic acid-chitosan microparticles for oral drug delivery applications. Poly (methacrylic acid)-chitosan (PMC) and poly(methacrylic acid-vinyl pyrrolidone)-chitosan
core +1 more source
Precise Design Strategies of Nanotechnologies for Controlled Drug Delivery
, 2022 Rapid advances in nanotechnologies are driving the revolution in controlled drug delivery. However, heterogeneous barriers, such as blood circulation and cellular barriers, prevent the drug from reaching the cellular target in complex physiologic ...
Shiyi Huang +3 more
core +1 more source
Current Status of Drug Delivery Systems for Antifungal Drugs [PDF]
, 2012 The number of deep-seated mycosis cases is increasing rapidly along with the extreme advanced technology and highly sophisticated treatment. High mortality of deep-seated mycosis is critical concern, and an appropriate strategy and usage of antifungals ...
河野, 茂, 泉川, 公一
core +1 more source
An in situ dual-anchoring strategy for enhanced immobilization of PD-L1 to treat autoimmune diseases
Nature Communications, 2023 Immune checkpoints play key roles in maintaining self-tolerance. Targeted potentiation of the checkpoint molecule PD-L1 through in situ manipulation offers clinical promise for patients with autoimmune diseases.
Shenqiang Wang +9 more
doaj +1 more source