Results 31 to 40 of about 6,495,283 (386)

Nano based drug delivery systems: recent developments and future prospects

Journal of Nanobiotechnology, 2018
Nanomedicine and nano delivery systems are a relatively new but rapidly developing science where materials in the nanoscale range are employed to serve as means of diagnostic tools or to deliver therapeutic agents to specific targeted sites in a ...
J. Patra, Gitishree Das, L. Fraceto, E. Campos, M. D. P. Rodriguez-Torres, L. Acosta-Torres, L. Díaz-Torres, R. Grillo, M. K. Swamy, Shivesh Sharma, S. Habtemariam, Han-Seung Shin   +11 more
semanticscholar   +1 more source

Intranasal drug delivery: opportunities and toxicologic challenges during drug development

Drug Delivery and Translational Research, 2021
Over the past 10 years, the interest in intranasal drug delivery in pharmaceutical R&D has increased. This review article summarises information on intranasal administration for local and systemic delivery, as well as for CNS indications.
Lea-Adriana Keller, Olivia M. Merkel, A. Popp   +2 more
semanticscholar   +1 more source

Translation of ionic liquids to be enteric nanoparticles for facilitating oral absorption of cyclosporine A

Bioengineering & Translational Medicine, 2023
Ionic liquids (ILs) attract more and more interests in improving drug transport across membrane, including transdermal, nasal, and oral delivery. However, some drawbacks of ILs impede the application in oral drug delivery, such as rapid precipitation of ...
Kaiheng Liu, Wenjuan Liu, Zirong Dong, Luyu Zhang, Qiuyu Li, Renjie Zhang, Haisheng He, Yi Lu, Wei Wu, Jianping Qi   +9 more
doaj   +1 more source

Positive-charge tuned gelatin hydrogel-siSPARC injectable for siRNA anti-scarring therapy in post glaucoma filtration surgery

Scientific Reports, 2021
Small interfering RNA (siRNA) therapy is a promising epigenetic silencing strategy. However, its widespread adoption has been severely impeded by its ineffective delivery into the cellular environment.
Yong Yao Chun, Zhu Li Yap, Li Fong Seet, Hiok Hong Chan, Li Zhen Toh, Stephanie W. L. Chu, Ying Shi Lee, Tina T. Wong, Timothy T. Y. Tan   +8 more
doaj   +1 more source

New generation of DNA-based immunotherapy induces a potent immune response and increases the survival in different tumor models

Journal for ImmunoTherapy of Cancer, 2021
Background Strategies to increase nucleic acid vaccine immunogenicity are needed to move towards clinical applications in oncology. In this study, we designed a new generation of DNA vaccines, encoding an engineered vesicular stomatitis virus ...
Alessandra Lopes, Sophie Ligot, Gaëlle Vandermeulen, Chiara Bastiancich, Mathilde Bausart, Laure Lambricht, Kevin Vanvarenberg, Bernard Ucakar, Bernard Gallez   +8 more
doaj   +1 more source

Lipid Nanoparticles for Drug Delivery

Advanced NanoBiomed Research, 2021
Lipid nanoparticles have attracted significant interests in the last two decades, and have achieved tremendous clinical success since the first clinical approval of Doxil in 1995.
Letao Xu, Xing Wang, Yun Liu, Guangze Yang, R. Falconer, Chun‐Xia Zhao   +5 more
semanticscholar   +1 more source

Prospects and challenges of extracellular vesicle-based drug delivery system: considering cell source

Drug Delivery, 2020
Extracellular vesicles (EVs), including exosomes, microvesicles, and apoptotic bodies, are nanosized membrane vesicles derived from most cell types.
Wanrong Meng, Chuanshi He, Yaying Hao, Linlin Wang, Ling Li, G. Zhu   +5 more
semanticscholar   +1 more source

Alginate electrodeposition onto three-dimensional porous Co-Ni films as drug delivery platforms [PDF]

, 2015
Three-dimensional porous Co–Ni films/alginate hybrid materials have been successfully prepared by electrodeposition to be used as a steerable magnetic device for drug delivery. Firstly, 3D porous Co–Ni films were prepared as substrates for the subsequent
García Torres, José Manuel, Gispert, Claudia, Gómez, Elvira, Vallés, Elisa   +3 more
core   +2 more sources

Intraperitoneal chemotherapy for peritoneal metastases : an expert opinion

, 2020
Introduction: The rationale for intraperitoneal (IP) drug delivery for patients with peritoneal metastases (PM) is based on the pharmacokinetic advantage resulting from the peritoneal-plasma barrier, and on the potential to adequately treat small, poorly
Braet, Helena, Ceelen, Wim, Remaut, Katrien, Van Ramshorst, Gabrielle, Willaert, Wouter   +4 more
core   +1 more source

Design of hybrid gels based on gellan-cholesterol derivative and P90G liposomes for drug depot applications [PDF]

, 2017
Gels are extensively studied in the drug delivery field because of their potential benefits in therapeutics. Depot gel systems fall in this area, and the interest in their development has been focused on long-lasting, biocompatible, and resorbable ...
Cencetti, Claudia, DI MEO, Chiara, Manca, Maria Letizia, Manconi, Maria, Matricardi, Pietro, Montanari, Elita, Palmieri, Francesca Romana, Zoratto, Nicole   +7 more
core   +2 more sources