Results 61 to 70 of about 1,710,318 (306)
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
A Note on the Trandermal Delivery of Clenbuterol [PDF]
, 1992 A modified diffusion/compartmental model has been used to simulate the transdermal uptake of clenbuterol from a matrix-type delivery device. The application of a fresh device every 7 days was found to produce a pseudo-steady state drug plasma profile ...
Göpferich, Achim, Lee, Geoffrey
core +1 more source
Polymer–Lipid Hybrid Nanosystems: An Emerging Advanced Therapeutic Tool
Advances in Polymer TechnologyPolymer–lipid hybrid (PLH) nanoparticles have become an appealing therapeutic delivery system owing to their special properties. These nanoparticles are made with polymer and lipid components and have garnered significant interest across therapeutic ...
Nnamdi Ikemefuna Okafor +3 more
doaj +1 more source
Journal for ImmunoTherapy of Cancer, 2019 Background DNA vaccines against cancer held great promises due to the generation of a specific and long-lasting immune response. However, when used as a single therapy, they are not able to drive the generated immune response into the tumor, because of ...
Alessandra Lopes +6 more
doaj +1 more source
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
FEBS Letters, EarlyView.The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
Modelling drug coatings: A parallel cellular automata model of ethylcellulose-coated microspheres [PDF]
, 2011 Pharmaceutical companies today face a growing demand for more complex drug designs. In the past few decades, a number of probabilistic models have been developed, with the aim of improving insight on microscopic features of these complex designs.
Bezbradica, Marija +2 more
core +2 more sources
Programmable biomaterials for dynamic and responsive drug delivery [PDF]
, 2016 Biomaterials are continually being designed that enable new methods for interacting dynamically with cell and tissues, in turn unlocking new capabilities in areas ranging from drug delivery to regenerative medicine. In this review, we explore some of the
Almquist, BD, Kiani, MT, Stejskalova, A
core +1 more source
ChemistryOpen, 2023 The choice of capping agents used during the synthesis process of quantum dots (QDs) can significantly influence their fate and fundamental properties.
Zohre Montaseri +3 more
doaj +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Cell-Penetrating Peptides, Electroporation, and Drug Delivery
, 2010 Certain short polycations, such as TAT and oligoarginine, rapidly pass through the plasma membranes of mammalian cells by a mechanism called transduction, as well as by endocytosis and macropinocytosis.
Cahill, Kevin
core +1 more source