Results 61 to 70 of about 6,495,283 (386)
Efficient Peroral Delivery of Insulin via Vitamin B12 Modified Trimethyl Chitosan Nanoparticles
Journal of Pharmacy & Pharmaceutical Sciences, 2015 PURPOSE: We investigated the effect of vitamin B12 (VB12) modification on the insulin absorption from trimethyl chitosan(TMC) nanoparticles (NPs) under the influence of mucus.
Zhiyang Ke +4 more
doaj +1 more source
Metal–Organic Framework Nanocarriers for Drug Delivery in Biomedical Applications
Nano-Micro Letters, 2020 Recent advances in biomedical applications of metal–organic framework (MOF) nanocarriers for drug delivery are summarized. State-of-the-art strategies to functionalize MOFs with therapeutic agents, as well as their merits and drawbacks, are ...
Yujia Sun +9 more
semanticscholar +1 more source
Transdermal drug delivery [PDF]
Nature Biotechnology, 2008 Transdermal drug delivery has made an important contribution to medical practice, but has yet to fully achieve its potential as an alternative to oral delivery and hypodermic injections. First-generation transdermal delivery systems have continued their steady increase in clinical use for delivery of small, lipophilic, low-dose drugs. Second-generation
Robert Langer, Mark R. Prausnitz
openaire +3 more sources
Picoliter-volume inkjet printing into planar microdevice reservoirs for low-waste, high-capacity drug loading. [PDF]
, 2017 Oral delivery of therapeutics is the preferred route for systemic drug administration due to ease of access and improved patient compliance. However, many therapeutics suffer from low oral bioavailability due to low pH and enzymatic conditions, poor ...
Bogdanoff, Derek B +6 more
core +1 more source
Making tau amyloid models in vitro: a crucial and underestimated challenge
FEBS Letters, EarlyView.This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source
Acta Pharmaceutica Sinica B, 2023 Intelligent responsive drug delivery system opens up new avenues for realizing safer and more effective combination immunotherapy. Herein, a kind of tumor cascade-targeted responsive liposome (NLG919@Lip-pep1) is developed by conjugating polypeptide ...
Chuan Hu +8 more
doaj
ChemistryOpen, 2023 The choice of capping agents used during the synthesis process of quantum dots (QDs) can significantly influence their fate and fundamental properties.
Zohre Montaseri +3 more
doaj +1 more source
Influence of excipients on spray-dried powders for inhalation [PDF]
, 2014 Two areas attracting considerable attention when developing effective pulmonary drug delivery systems include the improvement of aerosolisation efficiency of the inhaled formulation and the controlled release of drug from the formulation following ...
Adi +45 more
core +1 more source
FEBS Letters, EarlyView.Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke +2 more
wiley +1 more source
Recent advances in polymeric drug delivery systems
Biomaterials Research, 2020 Background Polymeric drug delivery systems have been achieved great development in the last two decades. Polymeric drug delivery has defined as a formulation or a device that enables the introduction of a therapeutic substance into the body ...
Y. Sung, S. W. Kim
semanticscholar +1 more source