Results 81 to 90 of about 6,454,646 (313)
Optimal loading of hydrogel-based drug-delivery systems [PDF]
arXiv, 2022 Drug-loaded hydrogels provide a means to deliver pharmaceutical agents to specific sites within the body at a controlled rate. The aim of this paper is to understand how controlled drug release can be achieved by tuning the initial distribution of drug molecules in a hydrogel. A mathematical model is presented for a spherical drug-loaded hydrogel.
arxiv
A general model of coupled drug release and tissue absorption for drug delivery devices [PDF]
, 2015 In this paper we present a general model of drug release from a drug delivery device and the subsequent transport in biological tissue. The model incorporates drug diffusion, dissolution and solubility in the polymer coating, coupled with diffusion ...
Mcginty, Sean, Pontrelli, Giuseppe
core +1 more source
Drug Delivery, 2023 Recently, various novel drug delivery systems have been developed to overcome ocular barriers in order to improve drug efficacy. We have previously reported that montmorillonite (MT) microspheres (MPs) and solid lipid nanoparticles (SLNs) loaded with the
Huamei Li +12 more
doaj +1 more source
A compact targeted drug delivery mechanism for a next generation wireless capsule endoscope [PDF]
, 2016 This paper reports a novel medication release and delivery mechanism as part of a next generation wireless capsule endoscope (WCE) for targeted drug delivery.
Constandinou, TG, Woods, S
core +2 more sources
Polymeric Nanoparticles for Drug Delivery: Recent Developments and Future Prospects
Nanomaterials, 2020 The complexity of some diseases—as well as the inherent toxicity of certain drugs—has led to an increasing interest in the development and optimization of drug-delivery systems.
B. Begines +6 more
semanticscholar +1 more source
Nature CommunicationsProteolytic targeting chimera (PROTAC) technology is a protein-blocking technique and induces antitumor effects, with potential advantages. However, its effect is limited by insufficient distribution and accumulation in tumors.
Fan Tong +10 more
doaj +1 more source
First-Principles Calculations on Monolayer WX2 (X = S, Se) as an Effective Drug Delivery Carrier for Anti- Tuberculosis Drugs [PDF]
arXiv, 2023 Tuberculosis (TB) remains a major global health concern, necessitating the exploration of novel drug delivery systems to combat the challenges posed by conventional approaches. We investigated the potential of monolayer transition metal dichalcogenides (TMDs) as an innovative platform for efficient and targeted delivery of antituberculosis drugs ...
arxiv
Multifunctional targeting micelle nanocarriers with both imaging and therapeutic potential for bladder cancer. [PDF]
, 2012 BackgroundWe previously developed a bladder cancer-specific ligand (PLZ4) that can specifically bind to both human and dog bladder cancer cells in vitro and in vivo. We have also developed a micelle nanocarrier drug-delivery system.
de Vere White, Ralph +8 more
core +2 more sources
Controlled drug delivery vehicles for cancer treatment and their performance
Signal Transduction and Targeted Therapy, 2018 Although conventional chemotherapy has been successful to some extent, the main drawbacks of chemotherapy are its poor bioavailability, high-dose requirements, adverse side effects, low therapeutic indices, development of multiple drug resistance, and ...
S. Senapati +3 more
semanticscholar +1 more source
Stimuli-responsive nanocarriers for drug delivery, tumor imaging, therapy and theranostics
Theranostics, 2020 In recent years, much progress has been motivated in stimuli-responsive nanocarriers, which could response to the intrinsic physicochemical and pathological factors in diseased regions to increase the specificity of drug delivery.
P. Mi
semanticscholar +1 more source