Results 81 to 90 of about 6,817,458 (407)

Intra-articular drug delivery systems for osteoarthritis therapy: shifting from sustained release to enhancing penetration into cartilage [PDF]

, 2022
Huirong Huang, Zijian Lou, Shimin Zheng, Jianing Wu, Qing Yao, Ruijie Chen, Longfa Kou, Daosen Chen   +7 more
openalex   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Controlled Release Bilayer Floating Effervescent and Noneffervescent Tablets Containing Levofloxacin and Famotidine

International Journal of Polymer Science
The present study is aimed at designing bilayer-floating tablets to improve the drug concentration in the stomach for enhanced therapeutic efficacy. The tablets are comprised of an upper layer of levofloxacin (466.5 mg) and a lower layer of famotidine ...
Muhammad Tufail, Kifayat Ullah Shah, Ikram Ullah Khan, Kamran Ahmad Khan, Shefaat Ullah Shah, Faisal Rashid, Jahangir Khan, Abdulrahman Alshammari, Abdullah F. Alasmari, Muhammad Shahid Riaz   +9 more
doaj   +1 more source

Cell-Penetrating Peptides, Electroporation, and Drug Delivery

, 2010
Certain short polycations, such as TAT and oligoarginine, rapidly pass through the plasma membranes of mammalian cells by a mechanism called transduction, as well as by endocytosis and macropinocytosis.
Cahill, Kevin
core   +1 more source

Prospects and challenges of extracellular vesicle-based drug delivery system: considering cell source

Drug Delivery, 2020
Extracellular vesicles (EVs), including exosomes, microvesicles, and apoptotic bodies, are nanosized membrane vesicles derived from most cell types.
Wanrong Meng, Chuanshi He, Yaying Hao, Linlin Wang, Ling Li, G. Zhu   +5 more
semanticscholar   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Preparation of TPM–NCs–gel and its effect on subcutaneous abscess caused by Staphylococcus aureus

Journal of Holistic Integrative Pharmacy
Objective: The insoluble compound 1,1′-(2,4,6-trihydroxy-1,3-phenylene)bis(3-methylbutan-1-one) (TPM) is used in preparing a TPM nanocrystals gel (TPM–NCs–gel), and its in vitro antibacterial activity and therapeutic effect on subcutaneous abscesses ...
Quanwei Xie, Feirong Zhou, Runan He, Lianbao Ye, Zonghao Lin, Xiangyu Nie, Yuanzheng Wei, Chuqin Yu   +7 more
doaj   +1 more source

Accurate and sensitive probing of onset of micellization based on absolute aggregation‐caused quenching effect

Aggregate, 2022
Probing the onset of micellization, or determining the critical micelle concentration (CMC), is of crucial importance while remains to be challenged by growing demand for extraordinary sensitivity and accuracy.
Haisheng He, Chang Liu, Jiang Ming, Yongjiu Lv, Jianping Qi, Yi Lu, Xiaochun Dong, Weili Zhao, Wei Wu   +8 more
doaj   +1 more source

Drug Delivery Systems based on hydrogels [PDF]

, 2017
Gel systems have found extensive applications in the medicinal/pharmaceutical field because of their ease of preparation, ability for modifications, and responsiveness to external chemical or physical stimuli.
Demadis, Konstantinos D.
core  

Bioactive SrO-SiO2 glass with well-ordered mesopores: Characterization, physiochemistry and biological properties [PDF]

, 2011
For a biomaterial to be considered suitable for bone repair it should ideally be both bioactive and have a capacity for controllable drug delivery; as such, mesoporous SiO2 glass has been proposed as a new class of bone regeneration material by virtue of
Cuniberti, Gianaurelio, Doert, Thomas, Fan, Wei, Gelinsky, Michael, Luo, Yongxiang, Schulze, Renate, Simon, Paul, Wu, Chengtie, Xiao, Yin   +8 more
core   +2 more sources