Results 61 to 70 of about 779,180 (303)
Performance of a Brief Assessment Tool for Identifying Substance Use Disorders [PDF]
Objective: Evaluation of the performance of a brief assessment tool for identifying substance use disorders. The Triage Assessment for Addictive Disorders (TAAD) is a triage instrument that provides professionals with a tool to evaluate indications of ...
Campbell, Todd +3 more
core +1 more source
Legal and illegal drug use among female sex workers in bar and club prostitution in Belgium: a quantitative and qualitative study [PDF]
Aims: This study describes the amounts and effects of drug use in bar and club sex work, and the use of healthcare for the drug-related needs of sex workers (SW). Methods: A cross-sectional study was carried out in Belgium.
Decorte, Tom +4 more
core +1 more source
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Background and objectives There is an increased burden of mental disorders, including substance use disorders (MSUD) in low- and middle-income countries (LMICs). Digital technology offers a viable avenue to scale up the services for MSUD in such settings.
Riya Kaur Bhatia +12 more
doaj +1 more source
Role of endocannabinoids in regulating drug dependence [PDF]
This review will discuss the latest knowledge of how the endocannabinoid system might be involved in treating addiction to the most common illicit drugs.
Parolaro D +3 more
core +1 more source
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Relationship of serum prolactin with severity of drug use and treatment outcome in cocaine dependence. [PDF]
RATIONALE: Alteration in serum prolactin (PRL) levels may reflect changes in central dopamine activity, which modulates the behavioral effects of cocaine.
Berrettini, Wade H. +6 more
core +1 more source
Female sexual dysfunction in patients with sub-stance-related disorders [PDF]
OBJECTIVE: To estimate the prevalence of female sexual dysfunction symptoms and the associated risk factors in a sample of patients with substance-related disorders admitted to a specialized in-patient care unit.
Diehl, Alessandra +2 more
core +4 more sources

