Results 141 to 150 of about 3,066,996 (254)

Sulfilimines: An Underexplored Bioisostere for Drug Design? [PDF]

J Med Chem
Arvidsson PI.
europepmc   +1 more source

From Qsar to Dynamics: A Data-Driven Design of Drug-Like Lactam-Based Hdac Inhibitors for Diffuse Large B-Cell Lymphoma

Josiah Joseph Isah, Adamu Uzairu, Sani Uba, Muhammad Ibrahim   +3 more
openalex   +1 more source

Exploring the macrocyclic chemical space for heuristic drug design with deep learning models. [PDF]

Commun Chem
Hu F, Jia X, Liao W, Chen Z, Bi H, Ge H, Liu D, Zhang R, Hu Y, Mei W, Zhao Z, Zhang K, Zhu L, Diao Y, Li H.   +14 more
europepmc   +1 more source

Crystal structures of native and inhibited forms of human cathepsin D: implications for lysosomal targeting and drug design.

, 1993
Eric T. Baldwin, Talapady N. Bhat, Sergei Gulnik, M.V. Hosur, Raymond C. Sowder, Raúl E. Cachau, Jack Collins, A M Silva, John W. Erickson   +8 more
openalex   +2 more sources

Medicinal chemistry perspectives on anticancer drug design based on clinical applications (2015-2025). [PDF]

RSC Adv
Al-Karmalawy AA, Eissa ME, Ashour NA, Yousef TA, Al Khatib AO, Hawas SS.   +5 more
europepmc   +1 more source

Design and testing of a device for drug infusion and collection of continuous or batch cerebrospinal fluid (CSF) in rats: Pharmacokinetic study of CSF fluorescein injected intravenously and infused minocycline

, 2015
Carlos Valdes, José Luís Martínez, Claudio Laurido   +2 more
openalex   +1 more source

Drug Design and Discovery: Principles and Applications [PDF]

, 2017
Shu‐Feng Zhou, Wei-Zhu Zhong
openalex   +1 more source

Computer-Aided Drug Design Across Breast Cancer Subtypes: Methods, Applications and Translational Outlook. [PDF]

Int J Mol Sci
Tian W, Hu Y, Gao X, Yang J, Jiang W.
europepmc   +1 more source

Is Mycobacterial InhA a Suitable Target for Rational Drug Design? [PDF]

ChemMedChem
Rizet J, Maveyraud L, Rengel D, Guillet V, Publicola G, Rodriguez F, Lherbet C, Mourey L.   +7 more
europepmc   +1 more source

Manifold-constrained nucleus-level denoising diffusion model for structure-based drug design. [PDF]

Proc Natl Acad Sci U S A
Liu S, Yan L, Du W, Liu W, Li Z, Guo H, Borgs C, Chayes J, Anandkumar A.   +8 more
europepmc   +1 more source