Results 221 to 230 of about 2,938,349 (358)

Sulfilimines: An Underexplored Bioisostere for Drug Design? [PDF]

J Med Chem
Arvidsson PI.
europepmc   +1 more source

Design of New Reactions and Its Application to Creative Drug Research

, 1993
Chikara Kaneko
openalex   +2 more sources

Iron‐dependent lysosomal LDL oxidation induces the expression of scavenger receptor A in human THP‐1 monocytes

FEBS Open Bio, EarlyView.
In human monocytic cells THP‐1, a limited uptake of native—not oxidized—LDL/VLDL induced expression of scavenger receptor A and cellular adhesion. Induction was inhibited by lysosomotropic (WR‐1065) and lipophilic (BHT) antioxidants and by siRNAs against ferritinophagy.
Martina Čierna, Richard Buchal, Martin Leníček, Amit Shachak, Jan Pláteník   +4 more
wiley   +1 more source

Computer-Aided Drug Design and Drug Discovery. [PDF]

Pharmaceuticals (Basel)
Mihai DP, Nitulescu GM.
europepmc   +1 more source

Analysing Drug Abuse with British Crime Survey Data: Modelling and Questionnaire Design Issues [PDF]

, 2000
Ziggy MacDonald, Stephen Pudney
openalex   +1 more source

An approach for coherent periodogram averaging of tilt‐series data for improved contrast transfer function estimation

FEBS Open Bio, EarlyView.
The contrast transfer function (CTF) is an imaging aberration that is a major resolution‐limiting factor in cryo‐electron microscopy (cryo‐EM). Precise CTF estimation is key to overcoming this limitation, but is particularly challenging in cryo‐electron tomography (cryo‐ET) data. Here, we present an approach for using geometric information to assist in
Sagar Khavnekar, William Wan
wiley   +1 more source

Structural bioinformatics for rational drug design. [PDF]

Res Pract Thromb Haemost
Mozaffari S, Moen A, Ng CY, Nicolaes GAF, Wichapong K.   +4 more
europepmc   +1 more source

Role of Pharmacokinetic and Transporter Studies in Drug Design.

, 1999
Yuichi Sugiyama, Hiroshi Suzuki, Kiyomi Ito   +2 more
openalex   +2 more sources

Novel reagents and reactions for drug design [PDF]

, 2000
Tracy J. Baker, Yosup Rew, Murray Goodman   +2 more
openalex   +1 more source

The role of circular RNAs in regulating cytokine signaling in cancer

FEBS Open Bio, EarlyView.
Cytokines present in the tumor microenvironment fuel cancer development. Aberrant expression of circRNAs contributes to cancer progression. Cytokines are involved in regulating circRNA biogenesis. Furthermore, aberrantly expressed circRNAs regulate the expression of ligands, receptors, and downstream effectors involved in cytokine signaling to promote ...
Vandana Joshi, Swati, Amit Mishra, Amaresh Panda, Vivek Sharma   +4 more
wiley   +1 more source