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Model-Informed Drug Development for Ligelizumab in Patients With Chronic Spontaneous Urticaria. [PDF]
CPT Pharmacometrics Syst PharmacolBienczak A +9 more
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KMT2A-rearranged leukemia: from mechanism to drug development. [PDF]
Exp HematolErnst P, S Kyei P, Yokoyama A.
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Enhancing Drug Development for Paediatric Pulmonary Hypertension-An Integrative Perspective. [PDF]
Pulm CircAbman SH +14 more
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Opportunities and risks associated with external comparator cohorts in clinical drug development in hematology. [PDF]
Blood Cancer JBaggio D +3 more
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Drug-Glycosidation and Drug Development
Mini-Reviews in Medicinal Chemistry, 2013Ideally a drug should be administered in a form that it exerts its pharmacological action at the target site using the lowest concentration possible and without undesirable effects. Drug targeting is the approach which is followed for the purpose. Among different approaches preparation of synthetic glycosides of target drug and administering them ...
Vijay K, Kapoor, Amanpreet, Kaur
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Antipsychotic Drug Development
2010Schizophrenia typically manifests itself with a wide array of symptoms--positive, negative, cognitive, and affective--and may also involve neurodevelopmental and neurodegenerative aspects. Each of these symptom dimensions may be derived from pathology at one or more receptor types, localized in different regions of the brain.
Dennis H, Kim, Stephen M, Stahl
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