Results 151 to 160 of about 516,097 (212)
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OR discrimination: A new drug discrimination method
European Journal of Pharmacology, 1982Rats were trained to respond on one of two levers for food (drug lever) after injections of either 0.04 mg/kg fentanyl or 10 mg/kg cocaine HCl, and to respond on the saline lever after saline injections. The acquisition data indicate that this OR discrimination is feasable in the rat, though it developed slowly due to a bias of responding on the drug ...
Francis C Colpaert, Paul A J Janssen
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Forgetting of a drug-conditional discrimination
Physiology and Behavior, 1979Abstract Rats were trained on a drug-conditional discrimination to escape footshock in a T maze. Over a period of days rats learned to approach one goal box while under a pentobarbital drug state and another while under a saline drug state. Retention of this discrimination was then assessed with the rat under either a pentobarbital or saline state ...
Norman E Spear, Gregory J Smith
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Drugs and the discrimination of duration
Psychopharmacology, 1979The effects of lysergic acid diethylamide (LSD), d-amphetamine (AMP), chlorpromazine (CPZ), and the most active isomer of marihuana (delta9 - THC) on timing behavior were analyzed with a two-choice, discrete trial procedure in which pigeons were trained to discriminate visual stimuli that differed with respect to duration ('long' vs. 'short').
J L, Altman, J B, Appel, W T, McGowan
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DRUG DISCRIMINATION IN NEUROBIOLOGY
Behavioural Pharmacology, 1998Areas of neurobiological interest are identified towards which drug discrimination (DD) studies have made important contributions. DD allows ligand actions to be analyzed at the whole organism level, with a neurobiological specificity that is exquisite and often unrivalled.
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Pharmacology Biochemistry and Behavior, 1998
Pigeons trained to discriminate methamphetamine from saline after a history of training to discriminate pentobarbital from saline responded on the drug key after both pentobarbital and methamphetamine, but the association of these drugs by reinforcing their discriminative stimulus responses on the same key did not influence their effects on either ...
M, Li, D E, McMillan
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Pigeons trained to discriminate methamphetamine from saline after a history of training to discriminate pentobarbital from saline responded on the drug key after both pentobarbital and methamphetamine, but the association of these drugs by reinforcing their discriminative stimulus responses on the same key did not influence their effects on either ...
M, Li, D E, McMillan
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Drug and Alcohol Dependence, 1985
Opioid agonists and agonist/antagonists comprise a heterogeneous body of compounds that can be partitioned into at least three groups on the basis of their discriminative stimulus properties in several animal species: (1) stimulus effects similar to those of morphine or fentanyl and blocked completely by low doses of antagonists, such as naloxone and ...
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Opioid agonists and agonist/antagonists comprise a heterogeneous body of compounds that can be partitioned into at least three groups on the basis of their discriminative stimulus properties in several animal species: (1) stimulus effects similar to those of morphine or fentanyl and blocked completely by low doses of antagonists, such as naloxone and ...
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Drugs, Discrimination, and Disability
SSRN Electronic Journal, 2010Whether addiction to prohibited drugs should be classified as a disability for the purposes of disability discrimination is a controversial question in Australia. The leading Australian case of Marsden v Human Rights Equal Opportunity Commission & Coffs Harbour & District Ex-Servicemen & Women's Memorial Club Ltd (HREOC, No H98/51, 30 August 1999 ...
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Drug discrimination and generalization in pigeons
Pharmacology Biochemistry and Behavior, 1977In a three-key operant conditioning situation six pigeons were trained to select the response key which was associated with each of three drug treatment conditions: d-amphetamine (2 mg/kg), pentobarbital (5 mg/kg), and saline. Thus, the drug state served as a discriminative stimulus for food reinforcement.
M R, Leberer, S C, Fowler
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Subjective and discriminative effects of drugs
Behavioural Pharmacology, 1991Human research using drug discrimination procedures is reviewed. Originally developed in the animal laboratory, drug discrimination procedures have been suggested to provide an index of subjective drug effects. Human research provides unique opportunities to assess the relationship of subjective and discriminative drug effects, since only in humans can
K.L., Preston, G.E., Bigelow
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