Results 1 to 10 of about 1,122,477 (316)

Determination of Residual Triflumezopyrim Insecticide in Agricultural Products through a Modified QuEChERS Method

Foods, 2021
A rapid and simple analytical method for triflumezopyrim, a new class of mesoionic insecticides and commercialized molecules from DuPont, was developed with a modified QuEChERS method.
Sung-Min Cho, Han-Sol Lee, Ji-Su Park, Su-Jung Lee, Hye-Sun Shin, Yun-Mi Chung, Ha-Na Choi, Yong-Hyun Jung, Jae-Ho Oh, Sang-Soon Yun   +9 more
doaj   +1 more source

Decoding kinase-adverse event associations for small molecule kinase inhibitors

Nature Communications, 2022
Small molecule kinase inhibitors (SMKIs) are being approved at a fast pace under expedited programs for anticancer treatment. Here, the authors employ a machine-learning model to examine the relationships between kinase targets and adverse events in the ...
Xiajing Gong, Meng Hu, Jinzhong Liu, Geoffrey Kim, James Xu, Amy McKee, Todd Palmby, R. Angelo de Claro, Liang Zhao   +8 more
doaj   +1 more source

Rewarding and Reinforcing Effects of 25H-NBOMe in Rodents

Brain Sciences, 2022
The drug 25H-NBOMe is a new psychoactive substance (NPS). The use of these substances is likely to pose a threat to public health because they elicit effects similar to those of known psychoactive substances with similar chemical structures.
Cheolmin Jo, Hyejin Joo, Dong-Hyun Youn, Jin Mook Kim, Young-Ki Hong, Na Young Lim, Kwan Soo Kim, Su-Jeong Park, Sun Ok Choi   +8 more
doaj   +1 more source

Establishment of analysis method for the quantification of residues of halquinol and its metabolites in livestock and fishery products using liquid chromatography–tandem mass spectrometry

Applied Biological Chemistry, 2023
In this study, an analysis method was established for the quantification of residues of halquinol and its metabolites in livestock and fishery products using liquid chromatography–tandem mass spectrometry (LC–MS/MS).
Tae Ho Lee, Sun Young Park, Ji Young Kim, Jang-Duck Choi, Guiim Moon   +4 more
doaj   +1 more source

Quality Evaluation of Pulsatilla chinensis Total Saponin Extracts via Quantitative Analysis of Multicomponents by Single Marker Method Combined with Systematic Quantified Fingerprint Method

Journal of Analytical Methods in Chemistry, 2022
Chinese medicine extracts are complex in composition. The combination of the quantitative analysis of multicomponents by single marker (QAMS) and the systematic quantified fingerprint method (SQFM) can be used for better quantitative analysis.
Long Chen, Suzhen Liu, Shuhan Feng, Liangliang Zhou, Zhenhua Chen   +4 more
doaj   +1 more source

Quality Appraisal of Ambulatory Oral Cephalosporin and Fluoroquinolone Use in the 16 German Federal States from 2014–2019

Antibiotics, 2021
Background: Despite concerns about causing bacterial resistance and serious side effects, oral cephalosporins and fluoroquinolones are still frequently prescribed in Germany.
Gabriele Gradl, Johanna Werning, Salka Enners, Marita Kieble, Martin Schulz   +4 more
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Considerations on Clinical Development and Regulatory of the Oversea License-in 
Anti-tumor Drugs

Chinese Journal of Lung Cancer, 2022
With the boom of China's innovative pharmaceutical industry, licensing-in model has gradually become an important research and development model for innovative pharmaceutical companies.
Xiao ZHAO, Ruimin HAO, Xin TONG, Limin ZOU, Ling TANG, Hong ZHANG, Lin XIA, Zhimin YANG   +7 more
doaj   +1 more source

Determination of Modified QuEChERS Method for Chlorothalonil Analysis in Agricultural Products Using Gas Chromatography–Mass Spectrometry (GC-MS/MS)

Foods, 2023
Chlorothalonil is an organochlorine fungicide that blocks the respiratory process of cells and persists in agricultural products because it is used extensively to prevent fungal diseases. An analytical method of chlorothalonil using the modified QuEChERS
Da-Young Yun, Ji-Yeon Bae, Chan-Woong Park, Gui-Hyun Jang, Won-Jo Choe   +4 more
doaj   +1 more source

Evaluating the potential of gold, silver, and silica nanoparticles to saturate mononuclear phagocytic system tissues under repeat dosing conditions

Particle and Fibre Toxicology, 2017
Background As nanoparticles (NPs) become more prevalent in the pharmaceutical industry, questions have arisen from both industry and regulatory stakeholders about the long term effects of these materials. This study was designed to evaluate whether gold (
James L. Weaver, Grainne A. Tobin, Taylor Ingle, Simona Bancos, David Stevens, Rodney Rouse, Kristina E. Howard, David Goodwin, Alan Knapton, Xiaohong Li, Katherine Shea, Sharron Stewart, Lin Xu, Peter L. Goering, Qin Zhang, Paul C. Howard, Jessie Collins, Saeed Khan, Kidon Sung, Katherine M. Tyner   +19 more
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Exploring racial disparities in treatment patterns and outcomes for patients with multiple myeloma using real world data

Blood Cancer Journal, 2022
This retrospective observational study evaluated racial disparities among Black and White patients with multiple myeloma (MM). We included patients from a longitudinal de-identified EHR-derived database who had ≥2 visits recorded on or after 1/1/2011 ...
Kathleen Maignan, Lola A. Fashoyin-Aje, Aracelis Z. Torres, Laura L. Fernandes, Thomas Gwise, Shrujal B. Baxi, James P. Roose, Donna R. Rivera, Yuan Li Shen, Paul G. Kluetz, Nicole J. Gormley   +10 more
doaj   +1 more source