Results 171 to 180 of about 18,950,887 (401)

Evaluation of microfilaricidal effects in the cornea from topically applied drugs in ocular onchocerciasis: Trials with levamisole and mebendazole. [PDF]

, 1978
B. R. Jones, John Anderson, H. Fuglsang
openalex   +1 more source

Establishment and large-scale validation of a three-dimensional tumor model on an array chip for anticancer drug evaluation. [PDF]

Front Pharmacol, 2022
Xiao RR, Jin L, Xie N, Luo P, Gao W, Tu P, Ai X.   +6 more
europepmc   +1 more source

Elucidating prognostic significance of purine metabolism in colorectal cancer through integrating data from transcriptomic, immunohistochemical, and single‐cell RNA sequencing analysis

Molecular Oncology, EarlyView.
Low expression of five purine metabolism‐related genes (ADSL, APRT, ADCY3, NME3, NME6) was correlated with poor survival in colorectal cancer. Immunohistochemistry analysis showed that low NME3 (early stage) and low ADSL/NME6 (late stage) levels were associated with high risk.
Sungyeon Kim, Myunghee Kang, Soyeon Jeong, Jisup Kim, Kyoung Oh Kim, Won‐Suk Lee, Jeong‐Heum Baek, Jung Ho Kim, Seungyoon Nam   +8 more
wiley   +1 more source

AN EXPERIMENTAL EVALUATION OF THE ANTICONVULSANT ACTIVITY OF SOME ANTIHISTAMINE DRUGS

, 1969
Vinod Saxena, Samhita Bapat, B. N. Dhawan   +2 more
openalex   +1 more source

Clinical review considerations of class I PI3K inhibitors in hematolymphatic malignancies by Center for Drug Evaluation. [PDF]

Chin J Cancer Res, 2022
Zou L, Qi Y, Tang L, Du Y, Xiang M, Chen X, Ma J, Yang Z.   +7 more
europepmc   +1 more source

Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma

Molecular Oncology, EarlyView.
This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu, Jianchao Wang, Fuqing Chen, Xuefeng Wang, Bin Lan, Ruyi Fu, Hong Wen, Fangfang Chen, Wei Hong, Tian‐Yu Tang, Ying He, Gang Chen, Jianyin Zhou, Hai‐Long Piao, Di Chen, Shu‐Yong Lin   +15 more
wiley   +1 more source

Genetic Characteristics of Multidrug-Resistant Salmonella Isolated from Poultry Meat in South Korea

Microorganisms
Given the lack of genetic characterization data for multidrug-resistant (MDR) Salmonella in South Korean poultry, we analyzed 53 MDR Salmonella strains from 1232 poultry meat samples (723 chicken, 509 duck) using whole-genome sequencing.
Haiseong Kang, Hansol Kim, Jonghoon Lee, Ji Hye Jeon, Seokhwan Kim, Yongchjun Park, Insun Joo, Hyochin Kim   +7 more
doaj   +1 more source

Optimal Medical Therapy With or Without Percutaneous Coronary Intervention to Reduce Ischemic Burden: Results From the Clinical Outcomes Utilizing Revascularization and Aggressive Drug Evaluation (COURAGE) Trial Nuclear Substudy

Circulation, 2008
L. Shaw, D. Berman, D. Maron, G. Mancini, S. Hayes, P. Hartigan, W. Weintraub, R. O'rourke, Marcin Dada, J. Spertus, B. Chaitman, J. Friedman, P. Slomka, G. Heller, G. Germano, G. Gosselin, P. Berger, W. Kostuk, R. Schwartz, M. Knudtson, E. Veledar, E. Bates, B. Mccallister, K. Teo, W. Boden   +24 more
semanticscholar   +1 more source

An Orthotopic Model of Uveal Melanoma in Zebrafish Embryo: A Novel Platform for Drug Evaluation. [PDF]

Biomedicines, 2021
Tobia C, Coltrini D, Ronca R, Loda A, Guerra J, Scalvini E, Semeraro F, Rezzola S.   +7 more
europepmc   +1 more source

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source