Results 181 to 190 of about 223,933 (345)

Transgenic murine models for the study of drug hypersensitivity reactions linked to HLA-I molecules. [PDF]

Curr Opin Allergy Clin Immunol, 2023
Puig M, Norcross MA.
europepmc   +1 more source

Advancing drug safety in psychiatry: insights from pharmacogenomics of hypersensitivity reactions [PDF]

Hamid Alhaj, Jana Samara, Alyamama Alnamous, Rama Karima, Maha Saber-Ayad   +4 more
openalex   +1 more source

Effects of High‐ and Low‐Fat Meals on the Bioavailability and Pharmacokinetics of Votoplam, a HTT Gene Splicing Modifier

Clinical Pharmacology in Drug Development, EarlyView.
Abstract Votoplam is a novel, orally bioavailable, small molecule HTT gene splicing modifier that is being developed for the treatment of Huntington's disease. This was a single dose, open‐label, two‐period, crossover food effect study that evaluated the effect of high‐ and low‐fat meals on 20 mg votoplam in healthy participants. There was a washout of
Lucy Lee, Amy‐Lee Richards, Nageswara Reddy, Brian Beers, Lee Golden, Ronald Kong   +5 more
wiley   +1 more source

Recognizing Drug Hypersensitivity in Pigmented Skin. [PDF]

Immunol Allergy Clin North Am, 2022
Lehloenya RJ, Phillips EJ, Pasieka HB, Peter J.   +3 more
europepmc   +1 more source

Nonimmediate Hypersensitivity Reaction to Rifaximin Confirmed With a Drug Challenge Test [PDF]

, 2021
B Moya, I García-Moguel, R Mielgo, L Herráez, J. E. Crespo   +4 more
openalex   +1 more source

Pediatric Developmental Safety Assessment: Are We Ready for the Next Thalidomide?

Clinical Pharmacology &Therapeutics, EarlyView.
Pediatric drug development has achieved remarkable success in the last 20 years with over 1,000 products studied in pediatric patients. This success has been driven in part by an increased understanding of pediatric disease processes. The aspect that has been largely overlooked is the potential adverse effect of new drugs on pediatric developmental ...
Gilbert J. Burckart, Susan M. Abdel‐Rahman, Gelareh Abulwerdi, Sherbet Samuels, Rebecca Racz, Mohamed A. Mohamoud, Nicholas P. Tatonetti   +6 more
wiley   +1 more source

Drug hypersensitivity syndrome induced by sulfasalazine: A case report. [PDF]

Medicine (Baltimore), 2022
Chen DH, Zhou HR, Zhang YG, Shen GY, Xu C, Guan CL.   +5 more
europepmc   +1 more source

The fundamental usage of drugs.Clinical pharmacology for a specialist.4.For the prevention of drug hypersensitivity.

, 1992
村中 正治
openalex   +2 more sources

Treatment of iron deficiency anemia: practical considerations [PDF]

, 2015
Rampton, D, Taylor, S
core   +1 more source

Population Pharmacokinetic and Exposure‐Efficacy Analysis of Baloxavir Marboxil for Influenza Treatment and Post‐Exposure Prophylaxis in Children

Clinical Pharmacology &Therapeutics, EarlyView.
Baloxavir acid (baloxavir), the active metabolite of the prodrug baloxavir marboxil, is a selective inhibitor of the influenza virus cap‐dependent endonuclease. The population pharmacokinetic (popPK) profile of baloxavir in adults/adolescents has been described previously.
Sylvie Retout, Stefan De Buck, Jacques Gaudreault, Sébastien Jolivet, Vincent Duval, Valérie Cosson, Marie‐Laure Delporte   +6 more
wiley   +1 more source