Results 11 to 20 of about 4,080,452 (353)
An Updated Review of the Molecular Mechanisms in Drug Hypersensitivity
Journal of Immunology Research, 2018 Drug hypersensitivity may manifest ranging from milder skin reactions (e.g., maculopapular exanthema and urticaria) to severe systemic reactions, such as anaphylaxis, drug reactions with eosinophilia and systemic symptoms (DRESS)/drug-induced ...
Chun-Bing Chen +6 more
doaj +2 more sources
Antioxidants, 2021 Adverse drug reactions are a major cause of morbidity and mortality. Of the great diversity of drugs involved in hypersensitivity drug reactions, the most frequent are non-steroidal anti-inflammatory drugs followed by β-lactam antibiotics.
Pedro Ayuso +2 more
doaj +2 more sources
Desensitization for the prevention of drug hypersensitivity reactions. [PDF]
Korean J Intern Med, 2022 Drug desensitization is the temporary induction of tolerance to a sensitized drug by administering slow increments of the drug, starting from a very small amount to a full therapeutic dose.
Kang SY, Seo J, Kang HR.
europepmc +2 more sources
Allergy. European Journal of Allergy and Clinical Immunology, 2023 Diagnosing immediate drug hypersensitivity reactions (IDHRs) can pose a significant challenge and there is an urgent need for safe and reliable tests.
C. Mayorga +11 more
semanticscholar +1 more source
Biomarkers of immediate drug hypersensitivity
Allergy. European Journal of Allergy and Clinical Immunology, 2023 Immediate drug hypersensitivity reactions (IDHRs) are a burden for patients and the health systems. This problem increases when taking into account that only a small proportion of patients initially labelled as allergic are finally confirmed after an ...
C. Mayorga +5 more
semanticscholar +1 more source
Viral infections and drug hypersensitivity
Allergy. European Journal of Allergy and Clinical Immunology, 2022 Virus infections and T‐cell‐mediated drug hypersensitivity reactions (DHR) can influence each other. In most instances, systemic virus infections appear first.
W. Pichler, M. Brüggen
semanticscholar +1 more source
An Updated Review of the Diagnostic Methods in Delayed Drug Hypersensitivity
Frontiers in Pharmacology, 2021 Delayed drug hypersensitivity reactions are clinically diverse reactions that vary from isolated benign skin conditions that remit quickly with no or symptomatic treatment, drug discontinuation or even continued drug treatment, to the other extreme of ...
A. Copaescu +4 more
semanticscholar +1 more source
The important role of non‐covalent drug‐protein interactions in drug hypersensitivity reactions
Allergy. European Journal of Allergy and Clinical Immunology, 2021 Drug hypersensitivity reactions (DHR) are heterogeneous and unusual immune reactions with rather unique clinical presentations. Accumulating evidence indicates that certain non‐covalent drug‐protein interactions are able to elicit exclusively effector ...
W. Pichler
semanticscholar +1 more source
International Journal of Molecular Sciences, 2021 Drug-induced hypersensitivity syndrome/drug reaction with eosinophilia and systemic symptoms (DIHS/DRESS) is a severe type of adverse drug eruption associated with multiorgan involvement and the reactivation of human herpesvirus 6, which arises after ...
F. Miyagawa, H. Asada
semanticscholar +1 more source
Comparison of methods for in-house screening of HLA*B57:01 to prevent abacavir hypersensitivity in HIV-1 care [PDF]
, 2015 Abacavir is a nucleoside reverse transcriptase inhibitor used as part of combination antiretroviral therapy in HIV-1-infected patients. Because this drug can cause a hypersensitivity reaction that is correlated with the presence of the HLA-B*57:01 ...
Bonczkowski, Pawel +18 more
core +7 more sources