Results 11 to 20 of about 3,966,363 (347)

Editorial: Biomarkers in Drug Hypersensitivity [PDF]

open access: yesFrontiers in Pharmacology, 2017
José A. G. Agúndez   +4 more
doaj   +7 more sources

Flow‐based basophil activation test in immediate drug hypersensitivity. An EAACI task force position paper

open access: yesAllergy. European Journal of Allergy and Clinical Immunology, 2023
Diagnosing immediate drug hypersensitivity reactions (IDHRs) can pose a significant challenge and there is an urgent need for safe and reliable tests.
C. Mayorga   +11 more
semanticscholar   +1 more source

An Updated Review of the Diagnostic Methods in Delayed Drug Hypersensitivity

open access: yesFrontiers in Pharmacology, 2021
Delayed drug hypersensitivity reactions are clinically diverse reactions that vary from isolated benign skin conditions that remit quickly with no or symptomatic treatment, drug discontinuation or even continued drug treatment, to the other extreme of ...
A. Copaescu   +4 more
semanticscholar   +1 more source

The important role of non‐covalent drug‐protein interactions in drug hypersensitivity reactions

open access: yesAllergy. European Journal of Allergy and Clinical Immunology, 2021
Drug hypersensitivity reactions (DHR) are heterogeneous and unusual immune reactions with rather unique clinical presentations. Accumulating evidence indicates that certain non‐covalent drug‐protein interactions are able to elicit exclusively effector ...
W. Pichler
semanticscholar   +1 more source

Associations of HLA-A and HLA-B with vancomycin-induced drug reaction with eosinophilia and systemic symptoms in the Han-Chinese population

open access: yesFrontiers in Pharmacology, 2022
Vancomycin is a commonly used antibiotic; however, it can cause life-threatening severe cutaneous adverse reactions, such as drug reaction with eosinophilia and systemic symptoms (DRESS).
Chuang-Wei Wang   +42 more
doaj   +1 more source

Pharmacogenetics of Drug Hypersensitivity [PDF]

open access: yesPharmacogenomics, 2010
Drug hypersensitivity reactions and severe cutaneous adverse drug reactions, such as Stevens-Johnson syndrome and toxic epidermal necrolysis, are examples of serious adverse drug reactions mediated through a combination of metabolic and immunological mechanisms that could traditionally not have been predicted based on the pharmacological ...
Phillips, E.J., Mallal, S.
openaire   +3 more sources

Profile of Drug Hypersensitivity Patients Hospitalized in Dr. Soetomo Hospital, Surabaya, Indonesia: Preliminary Data of 6 Months Observation

open access: yesFolia Medica Indonesiana, 2021
Drug hypersensitivity is defined as an untoward response to medication which is noxious and unintended, and which occurs at doses normally used in human either for the prophylaxis, diagnosis, or therapy of disease or for the modification of physiological
Nur Moya Isyroqiyyah   +2 more
doaj   +1 more source

Current Perspective Regarding the Immunopathogenesis of Drug-Induced Hypersensitivity Syndrome/Drug Reaction with Eosinophilia and Systemic Symptoms (DIHS/DRESS)

open access: yesInternational Journal of Molecular Sciences, 2021
Drug-induced hypersensitivity syndrome/drug reaction with eosinophilia and systemic symptoms (DIHS/DRESS) is a severe type of adverse drug eruption associated with multiorgan involvement and the reactivation of human herpesvirus 6, which arises after ...
F. Miyagawa, H. Asada
semanticscholar   +1 more source

Hypersensitivity reactions to small molecule drugs

open access: yesFrontiers in Immunology, 2022
Drug hypersensitivity reactions induced by small molecule drugs encompass a broad spectrum of adverse drug reactions with heterogeneous clinical presentations and mechanisms.
Jiayin Han   +6 more
doaj   +1 more source

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