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Multiple Drug Hypersensitivity [PDF]
Multiple drug hypersensitivity (MDH) is a syndrome that develops as a consequence of massive T-cell stimulations and is characterized by long-lasting drug hypersensitivity reactions (DHR) to different drugs.
W. Pichler+3 more
semanticscholar +4 more sources
An Updated Review of the Diagnostic Methods in Delayed Drug Hypersensitivity
Delayed drug hypersensitivity reactions are clinically diverse reactions that vary from isolated benign skin conditions that remit quickly with no or symptomatic treatment, drug discontinuation or even continued drug treatment, to the other extreme of ...
A. Copaescu+4 more
semanticscholar +1 more source
The important role of non‐covalent drug‐protein interactions in drug hypersensitivity reactions
Drug hypersensitivity reactions (DHR) are heterogeneous and unusual immune reactions with rather unique clinical presentations. Accumulating evidence indicates that certain non‐covalent drug‐protein interactions are able to elicit exclusively effector ...
W. Pichler
semanticscholar +1 more source
Editorial: Biomarkers in Drug Hypersensitivity [PDF]
José A. G. Agúndez+4 more
doaj +7 more sources
Vancomycin is a commonly used antibiotic; however, it can cause life-threatening severe cutaneous adverse reactions, such as drug reaction with eosinophilia and systemic symptoms (DRESS).
Chuang-Wei Wang+42 more
doaj +1 more source
Pharmacogenetics of Drug Hypersensitivity [PDF]
Drug hypersensitivity reactions and severe cutaneous adverse drug reactions, such as Stevens-Johnson syndrome and toxic epidermal necrolysis, are examples of serious adverse drug reactions mediated through a combination of metabolic and immunological mechanisms that could traditionally not have been predicted based on the pharmacological ...
Phillips, E.J., Mallal, S.
openaire +3 more sources
Drug hypersensitivity is defined as an untoward response to medication which is noxious and unintended, and which occurs at doses normally used in human either for the prophylaxis, diagnosis, or therapy of disease or for the modification of physiological
Nur Moya Isyroqiyyah+2 more
doaj +1 more source
Drug-induced hypersensitivity syndrome/drug reaction with eosinophilia and systemic symptoms (DIHS/DRESS) is a severe type of adverse drug eruption associated with multiorgan involvement and the reactivation of human herpesvirus 6, which arises after ...
F. Miyagawa, H. Asada
semanticscholar +1 more source