Results 21 to 30 of about 185,393 (349)
Journal of Immunology Research, 2020 Adult-onset Still’s disease (AOSD) is a rare and inflammatory disorder characterized by spiking fever, rash, arthritis, and multisystemic involvement. HLA has been shown to be associated with AOSD; however, it could not explain the innate immunity and ...
Yi-Ming Chen +9 more
doaj +1 more source
Drug Allergy in Children: What Should We Know? [PDF]
Clinical and Experimental Pediatrics, 2020 The drug allergy “label” may have a lifetime of consequences for a child. Many children with alleged drug allergies are proven to be tolerant to the culprit medication when challenged.
Ji Soo Park, Dong In Suh
doaj +1 more source
Association of immune response with efficacy and safety outcomes in adults with phenylketonuria administered pegvaliase in phase 3 clinical trials [PDF]
, 2018 Background: This study assessed the immunogenicity of pegvaliase (recombinant Anabaena variabilis phenylalanine [Phe] ammonia lyase [PAL] conjugated with polyethylene glycol [PEG]) treatment in adults with phenylketonuria (PKU) and its impact on safety ...
Atkinson, John P +14 more
core +2 more sources
An Updated Review of the Molecular Mechanisms in Drug Hypersensitivity
Journal of Immunology Research, 2018 Drug hypersensitivity may manifest ranging from milder skin reactions (e.g., maculopapular exanthema and urticaria) to severe systemic reactions, such as anaphylaxis, drug reactions with eosinophilia and systemic symptoms (DRESS)/drug-induced ...
Chun-Bing Chen +6 more
doaj +1 more source
Tuberculosis treatment-related lichenoid drug eruptions
International Journal of Mycobacteriology, 2022 Tuberculosis is one of the leading causes of death from infectious diseases in adults worldwide. Drug hypersensitivity in tuberculosis is an important problem affecting the treatment process.
Zeynep Yegin Katran +2 more
doaj +1 more source
The newly developed CRF1-receptor antagonists, NGD 98-2 and NGD 9002, suppress acute stress-induced stimulation of colonic motor function and visceral hypersensitivity in rats. [PDF]
, 2013 Corticotropin releasing factor receptor 1 (CRF1) is the key receptor that mediates stress-related body responses. However to date there are no CRF1 antagonists that have shown clinical efficacy in stress-related diseases.
Czimmer, József +7 more
core +7 more sources
Immediate-Type Hypersensitivity to Succinylated Corticosteroids [PDF]
, 2011 Background: Despite their frequent use, systemic corticosteroids have rarely elicited immediate-type reactions. Objective: We report two male patients, aged 26 and 70 years, respectively, with severe immediate-type hypersensitivity secondary to the ...
Przybilla, Bernhard +3 more
core +1 more source
HLA Association with Drug-Induced Adverse Reactions
Journal of Immunology Research, 2017 Adverse drug reactions (ADRs) remain a common and major problem in healthcare. Severe cutaneous adverse drug reactions (SCARs), such as Stevens–Johnson syndrome (SJS)/toxic epidermal necrolysis (TEN) with mortality rate ranges from 10% to more than 30 ...
Wen-Lang Fan +6 more
doaj +1 more source
Wound-Dressing-Based Antenna Inkjet-Printed Using Nanosilver Ink for Wireless Medical Monitoring
Micromachines, 2022 In this paper, we present a wound-dressing-based antenna fabricated via screen-printed and inkjet-printed technologies. To inkjet print a conductive film on wound dressing, it must be screen-printed, UV-curable-pasted, and hard-baked to provide ...
Chun-Bing Chen +6 more
doaj +1 more source
Multiple Drug Hypersensitivity [PDF]
International Archives of Allergy and Immunology, 2017 Multiple drug hypersensitivity (MDH) is a syndrome that develops as a consequence of massive T-cell stimulations and is characterized by long-lasting drug hypersensitivity reactions (DHR) to different drugs. The initial symptoms are mostly severe exanthems or drug rash with eosinophilia and systemic symptoms (DRESS).
Werner J. Pichler +3 more
openaire +3 more sources